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Published in: Abdominal Radiology 4/2010

01-08-2010

Esophageal cancer: pneumo-64-MDCT

Authors: Marina Ulla, Demetrio Cavadas, Inés Muñoz, Axel Beskow, Alberto Seehaus, Ricardo García-Mónaco

Published in: Abdominal Radiology | Issue 4/2010

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Abstract

Background

Pre-surgical characterization and staging of esophageal cancer with only one imaging method could be useful since gastric invasion determines the scope of resection and the kind of surgery to be performed. Our aim is to demonstrate the usefulness of Pneumo-64-MDCT (PnCT64) in the presurgical characterization of esophageal neoplasms in correlation with surgical findings.

Materials and methods

A total of 50 patients with diagnosis of esophageal neoplasm were prospectively studied. A 14 French Foley catheter was used transorally in all patients. Air was instilled through the catheter to achieve esophageal distension. A 64-row MDCT scan was performed and the tumor was characterized according to scope, shape and anatomic location by using multiplanar 3D reconstructions and virtual endoscopy. Wall infiltration and presence of adenopathies were analyzed.

Results

Adequate gastroesophageal distension was achieved in all patients. In 44/50 patients, wall thickening was observed, and in 34/50 regional adenopathies were found. In 29/50 patients the lesion was found in the lower third and in the gastroesophageal junction. The surgical correlation for wall infiltration was 85.7%.

Conclusions

PnCT64 proved to be useful and safe for identification of esophageal wall thickening and presurgical characterization. Optimal distension allowed definition of both upper and lower borders of the tumors located in the gastroesophageal junction, of utmost importance to determine the surgical approach.
Literature
1.
go back to reference Devesa S, Blot W, Fraumeni J, et al. (1998) Changing patterns in the incidence of esophageal and gastric carcinoma in the United States. Cancer 83:2049–2053CrossRefPubMed Devesa S, Blot W, Fraumeni J, et al. (1998) Changing patterns in the incidence of esophageal and gastric carcinoma in the United States. Cancer 83:2049–2053CrossRefPubMed
2.
go back to reference Pera M (2003) Trends in incidence and prevalence of specialized intestinal metaplasia, Barrett’s esophagus and adenocarcinoma of the gastroesophageal junction. World J Surg 27:999–1008CrossRefPubMed Pera M (2003) Trends in incidence and prevalence of specialized intestinal metaplasia, Barrett’s esophagus and adenocarcinoma of the gastroesophageal junction. World J Surg 27:999–1008CrossRefPubMed
3.
go back to reference Siewert JR, Feith M, Stein H (2005) Biologic and clinical variations of adenocarcinoma at the esophagogastric junction: relevance of a topographic anatomic subclassification. J Surg Oncol 90:139–146CrossRefPubMed Siewert JR, Feith M, Stein H (2005) Biologic and clinical variations of adenocarcinoma at the esophagogastric junction: relevance of a topographic anatomic subclassification. J Surg Oncol 90:139–146CrossRefPubMed
4.
go back to reference Kumbasar B (2002) Carcinoma of esophagus: radiologic diagnosis and staging. Eur J Radiol 42:170–180CrossRefPubMed Kumbasar B (2002) Carcinoma of esophagus: radiologic diagnosis and staging. Eur J Radiol 42:170–180CrossRefPubMed
5.
go back to reference Onbas¸ O, Eroglu A, Kantarci M, et al. (2006) Preoperative staging of esophageal carcinoma with multidetector CT and virtual endoscopy. Eur J Radiol 57:90–95CrossRefPubMed Onbas¸ O, Eroglu A, Kantarci M, et al. (2006) Preoperative staging of esophageal carcinoma with multidetector CT and virtual endoscopy. Eur J Radiol 57:90–95CrossRefPubMed
6.
go back to reference Mazzeo S, Caramella D, Gennai A, et al. (2004) Multidetector CT and virtual endoscopy in the evaluation of the esophagus. Abdominal Imaging 29:2–8CrossRefPubMed Mazzeo S, Caramella D, Gennai A, et al. (2004) Multidetector CT and virtual endoscopy in the evaluation of the esophagus. Abdominal Imaging 29:2–8CrossRefPubMed
7.
go back to reference Kim AY, Kim HJ, Ha HK (2005) Gastric cancer by multidetector row CT: preoperative staging. Abdom Imaging 30(4):465–472CrossRefPubMed Kim AY, Kim HJ, Ha HK (2005) Gastric cancer by multidetector row CT: preoperative staging. Abdom Imaging 30(4):465–472CrossRefPubMed
8.
go back to reference Prokop M (2003) Multislice CT: technical principles and future trends. Eur Radiol 5:3–13 Prokop M (2003) Multislice CT: technical principles and future trends. Eur Radiol 5:3–13
9.
go back to reference Rydberg J, Liang Y, Teague SD (2004) Fundamentals of multichannel CT. Semin Musculoskelet Radiol 8:137–146CrossRefPubMed Rydberg J, Liang Y, Teague SD (2004) Fundamentals of multichannel CT. Semin Musculoskelet Radiol 8:137–146CrossRefPubMed
10.
go back to reference Kohl G (2005) The evolution and state-of-the-art principles of multislice computed tomography. Proc Am Thorac Soc 2(6):470–476, 499–500 Kohl G (2005) The evolution and state-of-the-art principles of multislice computed tomography. Proc Am Thorac Soc 2(6):470–476, 499–500
11.
go back to reference Lightdale CJ (2000) Positron emission tomography: another useful test for staging esophageal cancer. J Clin Oncol 15(18):3199–3201 Lightdale CJ (2000) Positron emission tomography: another useful test for staging esophageal cancer. J Clin Oncol 15(18):3199–3201
12.
go back to reference Flanagan FL, Dehdashti F, Siegel BA, et al. (1997) Staging of esophageal cancer with 18F-fluorodeoxyglucose positron emission tomography. AJR Am J Roentgenol 168:417–424PubMed Flanagan FL, Dehdashti F, Siegel BA, et al. (1997) Staging of esophageal cancer with 18F-fluorodeoxyglucose positron emission tomography. AJR Am J Roentgenol 168:417–424PubMed
13.
go back to reference Carrascosa P, Capuñay C, Martin Lopez, et al. (2008) Esophageal stenosis; three dimensional multidetector CT and virtual endoscopy. Abdom Imaging 34(1):19–25CrossRef Carrascosa P, Capuñay C, Martin Lopez, et al. (2008) Esophageal stenosis; three dimensional multidetector CT and virtual endoscopy. Abdom Imaging 34(1):19–25CrossRef
15.
go back to reference Mahesh M (2002) Search for isotropic resolution in CT from conventional through multiple-row detector. Radiographics 22(4):949–962PubMed Mahesh M (2002) Search for isotropic resolution in CT from conventional through multiple-row detector. Radiographics 22(4):949–962PubMed
16.
go back to reference Hara AK, Johnson CD, MacCarty RL, et al. (2001) CT colonography: single versus multi-detector row imaging. Radiology 219(2):461–465.PubMed Hara AK, Johnson CD, MacCarty RL, et al. (2001) CT colonography: single versus multi-detector row imaging. Radiology 219(2):461–465.PubMed
17.
go back to reference PanebiancoV, Grazheani H, Iafrate F, et al. (2006) 3D CT protocol in the assessment of esophageal neoplastic lesions: can it improve TNM staging? Eur Radiol 16:414–421CrossRef PanebiancoV, Grazheani H, Iafrate F, et al. (2006) 3D CT protocol in the assessment of esophageal neoplastic lesions: can it improve TNM staging? Eur Radiol 16:414–421CrossRef
18.
go back to reference Millikan KW, Silverstein J, Hart V, et al. (1995) A 15-year review of esophagectomy for carcinoma of the esophagus and cardia. Arch Surg 130:617–624PubMed Millikan KW, Silverstein J, Hart V, et al. (1995) A 15-year review of esophagectomy for carcinoma of the esophagus and cardia. Arch Surg 130:617–624PubMed
19.
go back to reference William A, Killinger Jr., Thomas W, et al. (1996) Stage II esophageal carcinoma: the significance of T and N. J Thorac Cardiovasc Surg 111(5):935–940CrossRef William A, Killinger Jr., Thomas W, et al. (1996) Stage II esophageal carcinoma: the significance of T and N. J Thorac Cardiovasc Surg 111(5):935–940CrossRef
20.
go back to reference Rice TW, Boyce GA, Sivak MV (1991) Esophageal ultrasound and the preoperative staging of carcinoma of the esophagus. J Thorac Cardiovasc Surg 101:536PubMed Rice TW, Boyce GA, Sivak MV (1991) Esophageal ultrasound and the preoperative staging of carcinoma of the esophagus. J Thorac Cardiovasc Surg 101:536PubMed
21.
go back to reference Stein H, Feith M, Bruecher B, Naehrig J, et al. (2005) Early esophageal cancer: pattern of lymphatic spread and prognostic factors for long-term survival after surgical resection. Ann Surg 242:566–573PubMed Stein H, Feith M, Bruecher B, Naehrig J, et al. (2005) Early esophageal cancer: pattern of lymphatic spread and prognostic factors for long-term survival after surgical resection. Ann Surg 242:566–573PubMed
22.
go back to reference Stein H, Hutter J, Feith M, et al. (2007) Limited surgical resection and jejunal interposition for early adenocarcinoma of the distal esophagus. Semin Thorac Cardiovasc Surg 19:72–78.CrossRefPubMed Stein H, Hutter J, Feith M, et al. (2007) Limited surgical resection and jejunal interposition for early adenocarcinoma of the distal esophagus. Semin Thorac Cardiovasc Surg 19:72–78.CrossRefPubMed
Metadata
Title
Esophageal cancer: pneumo-64-MDCT
Authors
Marina Ulla
Demetrio Cavadas
Inés Muñoz
Axel Beskow
Alberto Seehaus
Ricardo García-Mónaco
Publication date
01-08-2010
Publisher
Springer-Verlag
Published in
Abdominal Radiology / Issue 4/2010
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-009-9554-3

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