Published in:
01-04-2016 | Erratum
Erratum to: PI3K/mTOR inhibition can impair tumor invasion and metastasis in vivo despite a lack of antiproliferative action in vitro: implications for targeted therapy
Published in: Breast Cancer Research and Treatment | Issue 2/2016
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In the original publication of the article, the Fig. 4c and d were published erroneously. The revised Fig. 4 is given in this erratum.
Fig. 4
Expression of a phosphomimetic, cell-cycle inert p27 mutant conveys resistance to PF1502. a Western analysis shows GFP-p27CK-T157DT198D (p27CK-DD) expression in 231 and 1833 (control represents empty-vector transfection). b Migration in 231 +/− PF1502 with or without p27CK-T157DT198D, mean +/− SEM (T-test of 231p27CK-DD (top) and 231 (bottom) with or without drug *p = 0.01, ‡ p = 0.11; 231CK-DD vs. 231 control p < 0.0001). c–d, Matrigel invasion of 231 (c) and 1833 cells (d) transduced with p27CK-DD, with and without 48 h PF1502 250 nM and graphed +/− SEM. (T-tests as indicated: *p = 0.003, ‡ p = 0.068 (left); *p = 0.0002, ‡ p = 0.064 (right)) (c, d)
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