Published in:
01-05-2015 | Erratum
Erratum to: Incidence of BRCA1 and BRCA2 non-founder mutations in patients of Ashkenazi Jewish ancestry
Published in: Breast Cancer Research and Treatment | Issue 1/2015
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In Table 2 of the original publication, the HGVS and legacy nomenclature were mismatched and the HGVS nomenclature did not correlate with data listed in the table. The corrected table is listed below.
Table 2
Distribution of non-founder mutations in patients of Ashkenazi Jewish and other ancestries
|
Gene
|
Mutationa
|
Total (all ancestries)b
|
AJ ancestry only (%)c
|
Partial AJ ancestry (%)d
|
All or partial AJ ancestry (%)e
|
|---|---|---|---|---|---|
|
BRCA2
|
c.3847_3848del (4075delGT)
|
321
|
15 (4.7)
|
6 (1.9)
|
21 (6.5)
|
|
BRCA2
|
c.1754del (1982delA)
|
10
|
7 (70.0)
|
1 (10.0)
|
8 (80.0)
|
|
BRCA1
|
c.4936del (5055delG)
|
21
|
7 (33.3)
|
2 (9.5)
|
9 (42.9)
|
|
BRCA2
|
c.9382C>T (R3128X)
|
227
|
7 (3.1)
|
4 (1.8)
|
11 (4.8)
|
|
BRCA2
|
c.4829_4830del (5057delTG)
|
27
|
6 (22.2)
|
5 (18.5)
|
11 (40.7)
|
|
BRCA2
|
c.2808_2811del (3036del4)
|
460
|
6 (1.3)
|
6 (1.3)
|
12 (2.6)
|