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International Urology and Nephrology
Published in: International Urology and Nephrology 3/2010

01-09-2010 | Nephrology - Translational Section

Epithelial–mesenchymal transition to be or not to be? Is the answer yes and no at the same time?

Authors: Cheng Zhu, Peter R. Mertens

Published in: International Urology and Nephrology | Issue 3/2010

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Excerpt

The process of epithelial–mesenchymal transition (EMT) is widely regarded as pivotal source of matrix-synthesizing (myo-)fibroblasts in renal fibrosis [1‐4]. Here, we highlight a recent publication in The American Journal of Pathology by Humphreys et al. [5] from the working group of J. Duffield at Harvard Medical School, which refined genetic models and obtained a closer look at EMT in the fibrosing kidney. …
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Cheng S, Lovett DH (2003) Gelatinase A (MMP-2) is necessary and sufficient for the renal tubular cell epithelial–mesenchymal transformation. Am J Pathol 162:1937–1949PubMed
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Metadata
Title
Epithelial–mesenchymal transition to be or not to be? Is the answer yes and no at the same time?
Authors
Cheng Zhu
Peter R. Mertens
Publication date
01-09-2010
Publisher
Springer Netherlands
Published in
International Urology and Nephrology / Issue 3/2010
Print ISSN: 0301-1623
Electronic ISSN: 1573-2584
DOI
https://doi.org/10.1007/s11255-010-9730-y

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