Published in:
Open Access
01-12-2003 | Editorial
Epidermal Growth Factor Receptor: A Novel Target for Anticancer Treatment
Authors:
Manoj Pandey, K Chandramohan
Published in:
World Journal of Surgical Oncology
|
Issue 1/2003
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Excerpt
The process of cell division, growth, differentiation and death is a highly regulated process. Several class of trans membrane receptors play a pivot role in this process, of these, epidermal growth factor receptor (EGFR) a member of Receptor Tyrosine Kinase (RTK) family are best known. These comprises of four receptors Erb B1/HER 1, Erb B2 / HER 2, Erb B3/ HER 3, and Erb B4 / HER 4. Of these HER 2 is the most favoured target. …