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Published in: Irish Journal of Medical Science (1971 -) 3/2018

01-08-2018 | Original Article

Epidemiology of chronic hepatitis B virus in Ireland using routinely collected surveillance and administrative data, 2004–2014

Authors: Caroline E. van Gemert, Niamh Murphy, Tara A. Mitchell, Margaret E. Hellard, Thornton Thornton

Published in: Irish Journal of Medical Science (1971 -) | Issue 3/2018

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Abstract

Background

Ireland has a low prevalence of chronic hepatitis B virus (HBV) infection; however, there are limited recently published epidemiological data. This study aimed to describe the epidemiology of chronic HBV in Ireland between 2004 and 2014 using routine surveillance data and identify and interrogate additional data sources in Ireland to complement the interpretation of HBV surveillance data.

Methods

Routinely collected passive surveillance data of notified cases of HBV infection were collated for 2004–2014. Additional data sources relating to primary liver cancer and cirrhosis were collated, including hospital discharge data (2005–2013), diagnoses of primary liver cancer (2004–2013), and deaths (2007–2014). Publicly available immigration (2004–2014) data were also collated.

Results

Between 2004 and 2014, a total of 7463 notifications of HBV were made in Ireland; the majority (91%) were classified as chronic cases. Notifications peaked in 2008 and decreased until 2013. Hospital discharges, new cancer registrations, and deaths from primary liver cancer and hospital discharges from cirrhosis have increased each year.

Discussion

The epidemiology of HBV in Ireland mirrors immigration patterns. Without a coordinated screening and care programme for priority populations, particularly for immigrants from high prevalence countries, it is likely that hospitalisations and deaths from HBV-attributable cirrhosis and primary liver cancer will continue to rise, with considerable associated public health expense.
Literature
5.
go back to reference GBD 2013 Mortality and Causes of Death Collaborators (2015) Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 385(9963):117–171CrossRef GBD 2013 Mortality and Causes of Death Collaborators (2015) Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 385(9963):117–171CrossRef
9.
go back to reference Global Health Sector Strategy on Viral Hepatitis 2016-2021: Towards ending viral hepatitis. Geneva: World Health Organization 2016 Global Health Sector Strategy on Viral Hepatitis 2016-2021: Towards ending viral hepatitis. Geneva: World Health Organization 2016
13.
go back to reference Central Statistics Office (2015) PEA15: annual population change by component and year. Dublin Central Statistics Office (2015) PEA15: annual population change by component and year. Dublin
17.
go back to reference Central Statistics Office (2015) PEA17: estimated immigration (persons in April) by sex, nationality and year. Dublin Central Statistics Office (2015) PEA17: estimated immigration (persons in April) by sex, nationality and year. Dublin
18.
go back to reference European Centre for Disease Prevention and Control (2010) Hepatitis B and C in the EU neighbourhood: prevalence, burden of disease and screening policies. ECDC, Stockholm European Centre for Disease Prevention and Control (2010) Hepatitis B and C in the EU neighbourhood: prevalence, burden of disease and screening policies. ECDC, Stockholm
22.
go back to reference European Centre for Disease Prevention and Control (2010) Hepatitis B and C in the EU neighbourhood: prevalence, burden of disease and screening policies. ECDC, Stockholm European Centre for Disease Prevention and Control (2010) Hepatitis B and C in the EU neighbourhood: prevalence, burden of disease and screening policies. ECDC, Stockholm
24.
go back to reference Department of Health and Children (2004) Communicable disease screening for asylum seekers Department of Health and Children (2004) Communicable disease screening for asylum seekers
26.
go back to reference Doyle S (2006) An evaluation and audit of the asylum seeker communicable disease screening service in the eastern region. Report submitted for Membership of the Faculty of Public Health Medicine of the Royal College of Physicians of Ireland Doyle S (2006) An evaluation and audit of the asylum seeker communicable disease screening service in the eastern region. Report submitted for Membership of the Faculty of Public Health Medicine of the Royal College of Physicians of Ireland
27.
go back to reference Brennan M, Boyle P, O'Brien A, Murphy K (2013) Health of asylum seekers: are we doing enough? Forum: Journal of the Irish College of General Practitioners. (11) Brennan M, Boyle P, O'Brien A, Murphy K (2013) Health of asylum seekers: are we doing enough? Forum: Journal of the Irish College of General Practitioners. (11)
28.
go back to reference Beasley RP, Hwang LY, Lee GC, Lan CC, Roan CH, Huang FY, Chen CL (1983) Prevention of perinatally transmitted hepatitis B virus infections with hepatitis B immune globulin and hepatitis B vaccine. Lancet 2(8359):1099–1102CrossRefPubMed Beasley RP, Hwang LY, Lee GC, Lan CC, Roan CH, Huang FY, Chen CL (1983) Prevention of perinatally transmitted hepatitis B virus infections with hepatitis B immune globulin and hepatitis B vaccine. Lancet 2(8359):1099–1102CrossRefPubMed
29.
go back to reference World Health Organization (2009) Hepatitis B vaccines: WHO position paper. Wkly Epidemiol Rec 40(84):405–420 World Health Organization (2009) Hepatitis B vaccines: WHO position paper. Wkly Epidemiol Rec 40(84):405–420
31.
go back to reference EASL (2017) 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection. J Hepatol 67(2):370–398CrossRef EASL (2017) 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection. J Hepatol 67(2):370–398CrossRef
Metadata
Title
Epidemiology of chronic hepatitis B virus in Ireland using routinely collected surveillance and administrative data, 2004–2014
Authors
Caroline E. van Gemert
Niamh Murphy
Tara A. Mitchell
Margaret E. Hellard
Thornton Thornton
Publication date
01-08-2018
Publisher
Springer London
Published in
Irish Journal of Medical Science (1971 -) / Issue 3/2018
Print ISSN: 0021-1265
Electronic ISSN: 1863-4362
DOI
https://doi.org/10.1007/s11845-017-1720-y

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