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Clinical Rheumatology
Published in: Clinical Rheumatology 6/2005

01-12-2005 | Case Report

Eosinophilic fasciitis successfully treated with cyclosporine

Authors: Aleksandra Bukiej, Jerzy Dropiński, Grzegorz Dyduch, Andrzej Szczeklik

Published in: Clinical Rheumatology | Issue 6/2005

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Abstract

We report on a 45-year-old female who developed eosinophilic fasciitis, characterized by scleroderma-like skin indurations, predominantly on the extremities and chest, with joint contractures and intermittent blood eosinophilia. Histologic examination revealed fibrosis of muscle fascia and eosinophilic infiltration. High-dose systemic corticosteroid therapy was ineffective, but cyclosporine treatment led to remission.
Literature
1.
Shulman LE (1974) Diffuse fasciitis with hypergammaglobulinemia and eosinophilia: a new syndrome? J Rheumatol 1 [Suppl]:46
2.
Mosconi S, Streit M, Bronimann M, Braathen LR (2002) Eosinophilic fasciitis (Shulman syndrome). Dermatology 205:204–206CrossRefPubMed
3.
Pouplin S, Daragon A, Le Loet X (1998) Treatment of eosinophilic fasciitis with methotrexate. J Rheumatol 25:606–607PubMed
4.
Dziadzio L, Kelly EA, Panzer SE, Jarjour N, Huttenlocher A (2003) Cytokine abnormalities in a patient with eosinophilic fasciitis. Ann Allergy Asthma Immunol 90:452–455PubMed
5.
Uckun A, Sipahi T, Akgun D, Oksal A (2002) Eosinophilic fasciitis successfully treated with oral hydroxyzine: a new therapeutic use of an old drug? Eur J Pediatr 161:118–119CrossRefPubMed
6.
Naschitz JE, Yeshurun D, Rosner J, Abrahamson JE, Misselevitcg I, Boss JH (1990) Treatment with cimetidine of atypical fasciitis panniculitis syndrome. Ann Rheum Dis 49:788–792PubMed
7.
Romano C, Rubegni P, Aloe G, Stanghellini E, Ascenzo GD, Andreassi L, Fimiani M (2003) Extracorporeal photochemotherapy in the treatment of eosinophilic fasciitis. JEADV 17:10–13PubMed
8.
Drosou A, Kirsner RS, Welsh E, Sullivan TP, Kerdel FA (2003) Use of infliximab, an anti-tumor necrosis alpha antibody, for inflammatory dermatoses. J Cutan Med Surg 7:382–386PubMed
9.
Plotz SG, Simon H, Darsow U, Simon D et al (2003) Use of anti-interleukin-5 antibody in the hypereosinophilic syndrome with eosinophilic dermatitis. N Engl J Med 349:2334–2339CrossRefPubMed
10.
Capella GL, Casa-Alberighi OD, Finzi AF (2001) Therapeutic concepts in clinical dermatology: cyclosporine A in immunomediated and other dermatoses. Int J Dermatol 40:551–559CrossRefPubMed
11.
Laneuville P (1992) Cyclosporin A induced remission of CD4+ T-CLL associated with eosinophilia and fasciitis. Br J Haematol 80:252–254PubMed
12.
Fleming CJ, Clarke P, Kemmet D (1997) Eosinophilic fasciitis with myelodysplasia responsive to treatment with cyclosporin. Br J Dermatol 136:297–299PubMed
13.
Peter RU, Ruzicka T (1992) Cyclosporin A in the therapy of inflammatory dermatoses. Hautarzt 43:687–694PubMed
14.
Gisslinger H, Burghuber OC, Stacher G, Schwarz W, Punzengruber C, Graninger W et al (1991) Efficacy of cyclosporin A in systemic sclerosis. Clin Exp Rheumatol 9:383–390PubMed
15.
Worl B, Hein R, Krieg T, Meurer M (1990) Cyclosporine A in localized and systemic sleroderma—a clinical study. Dermatologica 181:215–220PubMed
16.
Hayashi N, Igarashi A, Matsuyama T, Harada S (2000) Eosinophilic fasciitis following exposure to trichloroethylene: successful treatment with cyclosporin. Br J Dermatol 142:830–832CrossRefPubMed
17.
Lohi J, Kaharai VM, Keski-Oja J (1994) Cyclosporin A enhances cytokine and phorbol ester-induced fibroblast collagenase expression. J Invest Dermatol 102:938–944CrossRefPubMed
Metadata
Title
Eosinophilic fasciitis successfully treated with cyclosporine
Authors
Aleksandra Bukiej
Jerzy Dropiński
Grzegorz Dyduch
Andrzej Szczeklik
Publication date
01-12-2005
Publisher
Springer-Verlag
Published in
Clinical Rheumatology / Issue 6/2005
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-005-1099-4

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