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Published in: Indian Journal of Gastroenterology 6/2011

01-12-2011 | Editorial

Environmental factors associated with Crohn’s disease in India—there’s more to it than meets the eye

Author: Anjan Dhar

Published in: Indian Journal of Gastroenterology | Issue 6/2011

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Excerpt

Inflammatory bowel disease (IBD) has traditionally been considered a Western disease. However, the last 2 decades have seen an increase in the reports of both ulcerative colitis (UC) and Crohn’s disease (CD) from Asian countries [1]. Most of these reported series have been hospital-based with only one population-based survey by Sood et al. [2]. Time-trend data from Japan and China indicate a dramatic increase in the incidence of UC and a more gradual increase in that of CD [1]. In addition, a higher incidence of UC has been noted amongst second-generation Asian migrants in the United Kingdom [3]. This increase in the incidence and prevalence of IBD in Asia mirrors the epidemiological trend in the Western world that occurred 50 years ago Though increased awareness of IBD, better diagnostic facilities, and the growth of the specialty appear to have played a major factor for this increase in reported incidence, there is probably also a genuine increase in the incidence of both UC and CD [1]. …
Literature
1.
go back to reference Goh KL. Inflammatory Bowel disease: incidence and prevalence across Asia. In: Emerging Issues in Inflammatory Bowel Diseases, Falk Symposium 151, 3–11, Springer, 2006. Goh KL. Inflammatory Bowel disease: incidence and prevalence across Asia. In: Emerging Issues in Inflammatory Bowel Diseases, Falk Symposium 151, 3–11, Springer, 2006.
2.
go back to reference Sood A, Midha V, Sood N, et al. Incidence and prevalence of ulcerative colitis in Punjab, North India. Gut. 2003;52:1587–90.PubMedCrossRef Sood A, Midha V, Sood N, et al. Incidence and prevalence of ulcerative colitis in Punjab, North India. Gut. 2003;52:1587–90.PubMedCrossRef
3.
go back to reference Probert CS, Jayanthi V, Pinder D, et al. Epidemiological study of ulcerative procto-colitis in Indian migrants and the indigenous population of Leicestershire. Gut. 1992;33:687–93.PubMedCrossRef Probert CS, Jayanthi V, Pinder D, et al. Epidemiological study of ulcerative procto-colitis in Indian migrants and the indigenous population of Leicestershire. Gut. 1992;33:687–93.PubMedCrossRef
4.
go back to reference Feillet H, Bach J-F. Increased incidence of inflammatory bowel disease: the price of the decline of infectious burden? Curr Opin Gastroenterol. 2004;20:560–4.PubMedCrossRef Feillet H, Bach J-F. Increased incidence of inflammatory bowel disease: the price of the decline of infectious burden? Curr Opin Gastroenterol. 2004;20:560–4.PubMedCrossRef
5.
go back to reference Pugazhendhi S, Sahu MK, Subramanian V, Pulimood A, Ramakrishna BS. Environmental factors associated with Crohn’s disease in India. Indian J Gastroenterol. 2011;30. doi:10.1007/s12664-011-0145-1. Pugazhendhi S, Sahu MK, Subramanian V, Pulimood A, Ramakrishna BS. Environmental factors associated with Crohn’s disease in India. Indian J Gastroenterol. 2011;30. doi:10.​1007/​s12664-011-0145-1.
6.
go back to reference Gent AE, Heller MD, Grace RH, Swarbrick ET, Coggon D. Inflammatory bowel disease and domestic hygiene in infancy. Lancet. 1994;343:766–7.PubMedCrossRef Gent AE, Heller MD, Grace RH, Swarbrick ET, Coggon D. Inflammatory bowel disease and domestic hygiene in infancy. Lancet. 1994;343:766–7.PubMedCrossRef
7.
go back to reference Eckburg PB, Bik EM, Bernstein CN, et al. Diversity of the human intestinal microbial flora. Science. 2005;308:1635–8.PubMedCrossRef Eckburg PB, Bik EM, Bernstein CN, et al. Diversity of the human intestinal microbial flora. Science. 2005;308:1635–8.PubMedCrossRef
8.
9.
go back to reference O’Mahony S, Shanahan F. Enteric microbiota and small intestinal bacterial overgrowth. In: Feldman M, Friedman LS, Brandt LJ, editors. Sleisenger and Fordtran’s gastrointestinal and liver disease: pathophysiology, diagnosis, management. Philadelphia: Elsevier; 2010. p. 1769–78. O’Mahony S, Shanahan F. Enteric microbiota and small intestinal bacterial overgrowth. In: Feldman M, Friedman LS, Brandt LJ, editors. Sleisenger and Fordtran’s gastrointestinal and liver disease: pathophysiology, diagnosis, management. Philadelphia: Elsevier; 2010. p. 1769–78.
10.
go back to reference Turnbaugh PJ, Gordon JI. The core gut microbiome, energy balance and obesity. J Physiol. 2009;587:4153–8.PubMedCrossRef Turnbaugh PJ, Gordon JI. The core gut microbiome, energy balance and obesity. J Physiol. 2009;587:4153–8.PubMedCrossRef
11.
go back to reference Frank DN, St Amand AL, Feldman RA, Boedeker EC, Harpaz N, Pace NR. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci USA. 2007;104:13780–5.PubMedCrossRef Frank DN, St Amand AL, Feldman RA, Boedeker EC, Harpaz N, Pace NR. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci USA. 2007;104:13780–5.PubMedCrossRef
12.
go back to reference Gophna U, Sommerfeld K, Gophna S, Doolittle WF, Veldhuyzen van Zanten SJ. Differences between tissue-associated intestinal microfloras of patients with Crohn’s disease and ulcerative colitis. J Clin Microbiol. 2007;44:4136–41.CrossRef Gophna U, Sommerfeld K, Gophna S, Doolittle WF, Veldhuyzen van Zanten SJ. Differences between tissue-associated intestinal microfloras of patients with Crohn’s disease and ulcerative colitis. J Clin Microbiol. 2007;44:4136–41.CrossRef
13.
go back to reference Peterson DA, Frank DN, Pace NR, Gordon JI. Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases. Cell Host Microbe. 2008;3:417–27.PubMedCrossRef Peterson DA, Frank DN, Pace NR, Gordon JI. Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases. Cell Host Microbe. 2008;3:417–27.PubMedCrossRef
14.
go back to reference Darfeuille-Michaud A, Boudeau J, Bulois P, et al. High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease. Gastroenterology. 2004;127:412–21.PubMedCrossRef Darfeuille-Michaud A, Boudeau J, Bulois P, et al. High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease. Gastroenterology. 2004;127:412–21.PubMedCrossRef
15.
go back to reference Frank DN, Pace NR. Gastrointestinal microbiology enters the metagenomic era. Curr Opin Gastroenterol. 2008;24:4–10.PubMedCrossRef Frank DN, Pace NR. Gastrointestinal microbiology enters the metagenomic era. Curr Opin Gastroenterol. 2008;24:4–10.PubMedCrossRef
16.
go back to reference Schippa S, Conte MP, Borrelli O, et al. Dominant genotypes in mucosa-associated Escherichia coli strains from pediatric patients with inflammatory bowel disease. Inflamm Bowel Dis. 2009;15:661–72.PubMedCrossRef Schippa S, Conte MP, Borrelli O, et al. Dominant genotypes in mucosa-associated Escherichia coli strains from pediatric patients with inflammatory bowel disease. Inflamm Bowel Dis. 2009;15:661–72.PubMedCrossRef
Metadata
Title
Environmental factors associated with Crohn’s disease in India—there’s more to it than meets the eye
Author
Anjan Dhar
Publication date
01-12-2011
Publisher
Springer-Verlag
Published in
Indian Journal of Gastroenterology / Issue 6/2011
Print ISSN: 0254-8860
Electronic ISSN: 0975-0711
DOI
https://doi.org/10.1007/s12664-011-0147-z

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