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Published in: Calcified Tissue International 3/2015

01-03-2015 | Editorial

Emerging Impact of Skeletal Muscle in Health and Disease

Authors: Roger A. Fielding, Stuart H. Ralston, Rene Rizzoli

Published in: Calcified Tissue International | Issue 3/2015

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Excerpt

It has been over 60 years since Huxley first described the essential force transmitting properties of voluntary striated skeletal muscle [1]. At no time since then has the importance of skeletal muscle integrity been more pronounced. Although skeletal muscle comprises 40–50 % of total body mass, this tissue has been relatively understudied compared to brain, liver, cardiac, bone, and other tissues. Despite the fact that skeletal muscle is necessary for locomotion, oxygen consumption, whole-body energy metabolism, and substrate turnover and storage, a relative lack of attention has been paid to this tissue that is essential for many daily functions and activities [2]. …
Literature
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go back to reference Huxley H, Hanson J (1954) Changes in the cross-striations of muscle during contraction and stretch and their structural interpretation. Nature 173:973–976CrossRefPubMed Huxley H, Hanson J (1954) Changes in the cross-striations of muscle during contraction and stretch and their structural interpretation. Nature 173:973–976CrossRefPubMed
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go back to reference Wolfe RR (2006) The underappreciated role of muscle in health and disease. Am J Clin Nutr 84:475–482PubMed Wolfe RR (2006) The underappreciated role of muscle in health and disease. Am J Clin Nutr 84:475–482PubMed
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go back to reference Fielding RA, Vellas B, Evans WJ, Bhasin S, Morley JE, Newman AB, Abellan van Kan G, Andrieu S, Bauer J, Breuille D, Cederholm T, Chandler J, De Meynard C, Donini L, Harris T, Kannt A, Keime Guibert F, Onder G, Papanicolaou D, Rolland Y, Rooks D, Sieber C, Souhami E, Verlaan S, Zamboni M (2011) Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc 12:249–256CrossRefPubMed Fielding RA, Vellas B, Evans WJ, Bhasin S, Morley JE, Newman AB, Abellan van Kan G, Andrieu S, Bauer J, Breuille D, Cederholm T, Chandler J, De Meynard C, Donini L, Harris T, Kannt A, Keime Guibert F, Onder G, Papanicolaou D, Rolland Y, Rooks D, Sieber C, Souhami E, Verlaan S, Zamboni M (2011) Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc 12:249–256CrossRefPubMed
Metadata
Title
Emerging Impact of Skeletal Muscle in Health and Disease
Authors
Roger A. Fielding
Stuart H. Ralston
Rene Rizzoli
Publication date
01-03-2015
Publisher
Springer US
Published in
Calcified Tissue International / Issue 3/2015
Print ISSN: 0171-967X
Electronic ISSN: 1432-0827
DOI
https://doi.org/10.1007/s00223-015-9964-x

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