Published in:
Open Access
01-05-2011
Electrical modalities beyond pacing for the treatment of heart failure
Authors:
Richard N. Cornelussen, Vincent Splett, Ruth Nicholson Klepfer, Berthold Stegemann, Lilian Kornet, Frits W. Prinzen
Published in:
Heart Failure Reviews
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Issue 3/2011
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Abstract
In this review, we report on electrical modalities, which do not fit the definition of pacemaker, but increase cardiac performance either by direct application to the heart (e.g., post-extrasystolic potentiation or non-excitatory stimulation) or indirectly through activation of the nervous system (e.g., vagal or sympathetic activation). The physiological background of the possible mechanisms of these electrical modalities and their potential application to treat heart failure are discussed.