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Malaria Journal
Published in: Malaria Journal 1/2004

Open Access 01-12-2004 | Research

Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso

Authors: Olaf Müller, Corneille Traore, Bocar Kouyate

Published in: Malaria Journal | Issue 1/2004

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Abstract

The efficacy of pyrimethamine-sulfadoxine in the treatment of uncomplicated falciparum malaria in young children of a malaria holoendemic area in rural Burkina Faso is reported. Of 28 children treated with a standard single dose of pyrimethamine-sulfadoxine and followed-up over 14 days, only one Late Treatment Failure and four Late Parasitological Failures were observed, all with low-grade parasitaemia. In this area of very restricted use of pyrimethamine-sulfadoxine, the drug appears to be still sufficiently effective in the treatment of malaria. These findings provide further evidence for the justification of continued use of pyrimethamine-sulfadoxine as a second-line treatment for malaria in Burkina Faso.
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Metadata
Title
Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso
Authors
Olaf Müller
Corneille Traore
Bocar Kouyate
Publication date
01-12-2004
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2004
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/1475-2875-3-10

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Keynote webinar | Spotlight on medication adherence

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