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Critical Care
Published in: Critical Care 1/2011

Open Access 01-02-2011 | Poster presentation

Effects of tigecycline and doxycycline in porcine endotoxemia

Authors: M Von Seth, J Sjölin, A Larsson, M Eriksson, M Lipcsey

Published in: Critical Care | Special Issue 1/2011

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Excerpt

Tigecycline, the first drug in a new class of antibiotics, the glycylcyclines, is used in the treatment of severe abdominal and connective tissue infections. Tetracyclines, having a structure-activity relationship with tigecycline, exert anti-inflammatory effects [1]. Some laboratory studies suggest that tigecycline may have anti-inflammatory properties in sepsis, but this has not previously been explored in a large animal integrative intensive care model. …
Literature
1.
Metadata
Title
Effects of tigecycline and doxycycline in porcine endotoxemia
Authors
M Von Seth
J Sjölin
A Larsson
M Eriksson
M Lipcsey
Publication date
01-02-2011
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 1/2011
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc9656

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