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Immunity & Ageing
Published in: Immunity & Ageing 1/2012

Open Access 01-12-2012 | Research

Effects of life events and stress on neutrophil functions in elderly men

Authors: Kazumasa Tsukamoto, Kazuhiko Machida

Published in: Immunity & Ageing | Issue 1/2012

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Abstract

Background

Psychological stress or life events might significantly decrease neutrophil function in elderly individuals and lead to infectious diseases. However, relationships between these factors have not been examined in detail.
We investigated the relationships between neutrophil function measured using the nitroblue tetrazolium (NBT) reduction test and measurements of psychological stress and life events among 81 men aged over 60 years.

Results

The numbers and scores for life events were significantly higher (p < 0.01, respectively) in a group with values reflecting phagocytosis below the median than in a control group.

Conclusions

Chronic psychological stress due to life events decreases neutrophil functions among elderly men.
Appendix
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Metadata
Title
Effects of life events and stress on neutrophil functions in elderly men
Authors
Kazumasa Tsukamoto
Kazuhiko Machida
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Immunity & Ageing / Issue 1/2012
Electronic ISSN: 1742-4933
DOI
https://doi.org/10.1186/1742-4933-9-13

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