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Open Access 01-12-2013 | Study protocol

Effects of acupuncture treatment on depression insomnia: a study protocol of a multicenter randomized controlled trial

Authors: Yuan-Fang Chen, Jian-Hua Liu, Neng-Gui Xu, Zhao-Hui Liang, Zhen-Hua Xu, Shu-Jun Xu, Wen-Bin Fu

Published in: Trials | Issue 1/2013

Abstract

Background

More than 70% of patients with depression who see their doctors experience insomnia. Insomnia treatment is a very important link for depression treatment. Furthermore, antidepression treatment is also important for depression insomnia. In acupuncture, LU-7 (Lie Que) and KID-6 (Zhao Hai), which are two of the eight confluence points in meridian theory, are used as main points. An embedded needle technique is used, alternately, at two groups of points to consolidate the treatment effect. These two groups of points are BL-15 (Xin Shu) with BL-23 (Shen Shu) and BL-19 (Dan Shu) with N-HN-54 (An Mian). The effectiveness of these optimized acupuncture formulas is well proven in the practice by our senior acupuncturists in Guangdong Provincial Hospital of TCM. This study has been designed to examine whether this set of optimized clinical formulas is able to increase the clinical efficacy of depression insomnia treatment.

Methods/design

In this randomized controlled multicenter trial, all the eligible participants are diagnosed with depression insomnia. All participants are randomly assigned to one of two groups in a ratio of 1:1 and receive either conventional acupuncture treatment or optimized acupuncture treatment. Patients are evaluated using the Pittsburgh Sleep Quality Index(PSQI)and the Hamilton rating scale(HAMD) for depression. The use of antidepression and hypnotics drugs is also considered. Results are obtained at the start of treatment, 1 and 2 months after treatment has begun, and at the end of treatment. The entire duration of the study will be approximately 36 months.

Discussion

A high quality of trial methodologies is utilized in the study, and the results may provide better evidence for the effectiveness of acupuncture as a treatment for depression insomnia. The optimized acupuncture formula has potential benefits in increasing the efficacy of treating depression insomnia.

Trial registration

The trial was registered in Chinese Clinical Trial Register (ChiCR-TRC-00000481) on 12 August 2009.

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Title: Effects of acupuncture treatment on depression insomnia: a study protocol of a multicenter randomized controlled trial
Authors: Yuan-Fang Chen
Jian-Hua Liu
Neng-Gui Xu
Zhao-Hui Liang
Zhen-Hua Xu
Shu-Jun Xu
Wen-Bin Fu
Publication date: 01-12-2013
Publisher: BioMed Central
Published in: Trials / Issue 1/2013
Electronic ISSN: 1745-6215
DOI: https://doi.org/10.1186/1745-6215-14-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Effects of acupuncture treatment on depression insomnia: a study protocol of a multicenter randomized controlled trial

Abstract

Background

Methods/design

Discussion

Trial registration

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods/design

Discussion

Trial registration

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