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Antimicrobial Resistance & Infection Control

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Open Access 01-12-2017 | Research

Effectiveness of surface coatings containing silver ions in bacterial decontamination in a recovery unit

Authors: Rafael Manuel Ortí-Lucas, Julio Muñoz-Miguel

Published in: Antimicrobial Resistance & Infection Control | Issue 1/2017

Abstract

Background

HAIs remain a frequent complication for hospitalised patients and pose a challenge that must be tackled by our health systems.

Methods

Quasi-experimental study. In order to determine the antimicrobial effectiveness of surface coating agents containing silver ions (BactiBlock®) the degree of contamination of several surfaces in two ICU wards was compared.

The association between application of Bactiblock® and surface contamination was analysed using a relative risk (RR). Multivariate logistic regressions were performed for each product applied and each sampling location to adjust for the RR of the contamination of surfaces treated with Bactiblock® for the independent variables.

Results

Surface contamination was observed in 31.5% of treated samples and 27.4 of untreated samples. Contamination was equally prominent on bedside Tables (38.7%), bed rails (38.4%) and sinks (38.3%), while the walls showed minimum contamination (2.6%). For beds under isolation protocols, contamination was higher (32.6%) than when no protocol was followed (26.5%) but the difference was not significant (p = 0.148). After stratification for application method and adjusting the multivariate models for period of the study and presence of isolated patients, the risk of contamination after the intervention increased when the coating agent was applied using a spray (OR = 1.79; 95% CI: 1.08-2.95, particularly in a dry and rugged surface such as that of bedside Tables (OR = 2.59; 95% CI: 1.22-5.52); and decreased when the product was applied using a roller on a smooth and continuously cleaned (or wet) Surface (OR = 0.42; 95% CI: 0.19-0.92).

Conclusion

Coating of hospital surfaces with substances containing silver ions may reduce bacterial growth. However, the effectiveness of the coating agent is affected by application method and environmental conditions and the type and cleanness of the surface.

Schabrun S, Chipchase L. Healthcare equipment as a source of nosocomial infection: a systematic review. J Hosp Infect. 2006;63(3):239–45. doi:10.1016/j.jhin.2005.10.013.CrossRefPubMed

Weinstein RA. Epidemiology and control of nosocomial infections in adult intensive care units. Am J Med. 1991;91(3B):179S–84S.CrossRefPubMed

Kramer A, Schwebke I, Kampf G. How long do nosocomial pathogens persist on inanimate surfaces? A systematic review. BMC Infect Dis. 2006;6(1):130. doi:10.1186/1471-2334-6-130.CrossRefPubMedPubMedCentral

Dancer SJ, White LF, Lamb J, Girvan EK, Robertson C. Measuring the effect of enhanced cleaning in a UK hospital: a prospective cross-over study. BMC Med. 2009;7(1):28. doi:10.1186/1741-7015-7-28.CrossRefPubMedPubMedCentral

Sehulster L, Chinn RYW. Guidelines for environmental infection control in health-care facilities. Morb Mortal Wkly Rep. 2003;52(RR10):1–42.

French G, Otter J, Shannon K, Adams NM, Watling D, Parks M. Tackling contamination of the hospital environment by methicillin-resistant Staphylococcus aureus (MRSA): a comparison between conventional terminal cleaning and hydrogen peroxide vapour decontamination. J Hosp Infect. 2004;57(1):31–7. doi:10.1016/j.jhin.2004.03.006.CrossRefPubMed

Denton M, Wilcox M, Parnell P, et al. Role of environmental cleaning in controlling an outbreak of Acinetobacter Baumannii on a neurosurgical intensive care unit. J Hosp Infect. 2004;56(2):106–10. doi:10.1016/j.jhin.2003.10.017.CrossRefPubMed

Griffith CJ, Cooper RA, Gilmore J, Davies C, Lewis M. An evaluation of hospital cleaning regimes and standards. J Hosp Infect. 2000;45(1):19–28. doi:10.1053/jhin.1999.0717.CrossRefPubMed

Carling PC, Bartley JM. Evaluating hygienic cleaning in health care settings: what you do not know can harm your patients. Am J Infect Control. 2010;38(5):S41–50. doi:10.1016/j.ajic.2010.03.004.CrossRefPubMed

10.

Humphreys H. Self-disinfecting and Microbiocide-impregnated surfaces and fabrics: what potential in interrupting the spread of healthcare-associated infection? Clin Infect Dis. 2014;58(6):848–53. doi:10.1093/cid/cit765.CrossRefPubMed

11.

Jiménez-Martín S., Andrea-Viola A. El sistema de salud en España en perspectiva comparada 2014.

12.

Page K, Wilson M, Parkin IP. Antimicrobial surfaces and their potential in reducing the role of the inanimate environment in the incidence of hospital-acquired infections. J Mater Chem. 2009;19(23):3819. doi:10.1039/b818698g.CrossRef

13.

Sanborn WR. The relation of surface contamination to the transmission of disease. Am J Public health nations health. Am J Public Health. 1963;53(8):1278–83.CrossRef

14.

Dancer SJ. Importance of the environment in meticillin-resistant Staphylococcus aureus acquisition: the case for hospital cleaning. Lancet Infect Dis. 2008;8(2):101–13. doi:10.1016/S1473-3099(07)70241-4.CrossRefPubMed

15.

Monte-Serrano M, Fernandez-Saiz P, Ortí-Lucas RM. Effective Antimicrobial Coatings Containing Silver-Based Nanoclays and Zinc Pyrithione. J Microb Biochem Technol 2015;7(6). doi:10.4172/1948-5948.1000245.

16.

Haggstrom JA, Klabunde KJ, Marchin GL. Biocidal properties of metal oxidenanoparticles and their halogenadducts. Nano. 2010;2(3):399–405. doi:10.1039/B9NR00245F.

17.

Casey AL, Adams D, Karpanen TJ, et al. Role of copper in reducing hospital environment contamination. J Hosp Infect. 2010;74(1):72–7. doi:10.1016/j.jhin.2009.08.018.CrossRefPubMed

18.

Paul M, Shani V, Muchtar E, Kariv G, Robenshtok E, Leibovici L. Systematic review and meta-analysis of the efficacy of appropriate empiric antibiotic therapy for sepsis. Antimicrob Agents Chemother. 2010;54(11):4851–63. doi:10.1128/AAC.00627-10.CrossRefPubMedPubMedCentral

19.

Dancer SJ. Controlling hospital-acquired infection: focus on the role of the environment and new technologies for decontamination. Clin Microbiol Rev. 2014;27(4):665–90. doi:10.1128/CMR.00020-14.CrossRefPubMedPubMedCentral

20.

Taylor L, Phillips P, Hastings R. Reduction of bacterial contamination in a healthcare environment by silver antimicrobial technology. J Infect Prev. 2009;10(1):6–12. doi:10.1177/1757177408099083.CrossRef

21.

Chopra I. The increasing use of silver-based products as antimicrobial agents: a useful development or a cause for concern? J Antimicrob Chemother. 2007;59(4):587–90. doi:10.1093/jac/dkm006.CrossRefPubMed

22.

Percival SL, Bowler PG, Russell D. Bacterial resistance to silver in wound care. J Hosp Infect. 2005;60(1):1–7. doi:10.1016/j.jhin.2004.11.014.CrossRefPubMed

23.

Malik RE, Cooper RA, Griffith CJ. Use of audit tools to evaluate the efficacy of cleaning systems in hospitals. Am J Infect Control. 2003;31(3):181–7.CrossRefPubMed

24.

Hartemann P, Hoet P, Proykova A, et al. "Nanosilver: Safety, Health and Environmental Effects and Role in Antimicrobial Resistance." Materials Today 18.3. 2015:122-23.

25.

Morgan DJ, Liang SY, Smith CL, et al. Frequent multidrug-resistant Acinetobacter Baumannii contamination of gloves, gowns, and hands of healthcare workers. Infect Control Hosp Epidemiol. 2010;31(7):716–21. doi:10.1086/653201.CrossRefPubMedPubMedCentral

26.

Li L, Mendis N, Trigui H, Oliver JD, Faucher SP. The importance of the viable but non-culturable state in human bacterial pathogens. Front Microbiol. 2014;5 doi:10.3389/fmicb.2014.00258.

27.

Shiomori T, Miyamoto H, Makishima K, et al. Evaluation of bedmaking-related airborne and surface methicillin-resistant Staphylococcus aureus contamination. J Hosp Infect. 2002;50(1):30–5. doi:10.1053/jhin.2001.1136.CrossRefPubMed

28.

Best EL, Fawley WN, Parnell P, Wilcox MH. The potential for airborne dispersal of Clostridium Difficile from symptomatic patients. Clin Infect Dis. 2010;50(11):1450–7. doi:10.1086/652648.CrossRefPubMed

29.

Who. Guidelines on hand hygiene in health care. First global patient safety challenge clean care is safer care. World Health. 2009;30(1):270. doi:10.1086/600379.

Title: Effectiveness of surface coatings containing silver ions in bacterial decontamination in a recovery unit
Authors: Rafael Manuel Ortí-Lucas
Julio Muñoz-Miguel
Publication date: 01-12-2017
Publisher: BioMed Central
Published in: Antimicrobial Resistance & Infection Control / Issue 1/2017
Electronic ISSN: 2047-2994
DOI: https://doi.org/10.1186/s13756-017-0217-9

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Abstract

Background

Methods

Results

Conclusion

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