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Head and Neck Pathology
Published in: Head and Neck Pathology 3/2018

01-09-2018 | Special Issue: Ear

Ear and Temporal Bone Pathology: Neural, Sclerosing and Myofibroblastic Lesions

Authors: A. N. Flaman, J. K. Wasserman, D. H. Gravel, B. M. Purgina

Published in: Head and Neck Pathology | Issue 3/2018

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Abstract

Neural, sclerosing, and myofibroblastic lesions of the ear and temporal bone present diagnostic challenges for both clinicians and pathologists due to significant overlap in their clinical presentations, histologic appearances, and immunohistochemical profiles. While some of these lesions, such as schwannomas, are relatively common, others are rendered even more difficult because they are encountered very rarely in routine surgical pathology practice. This review is intended to provide an update on the pathology of some of the most commonly encountered primary diagnostic entities for the ear and temporal bone, and includes the following neural lesions: schwannoma, meningioma, and encephalocele/meningocele. Sclerosing lesions that will be discussed include spindle cell and sclerosing rhabdomyosarcoma, sclerosing epithelioid fibrosarcoma, and sclerosing paraganglioma. Finally, myofibroblastic lesions that will be reviewed are nodular fasciitis, IgG4-related disease, and solitary fibrous tumor. For each of these lesions, the differential diagnosis and useful ancillary tests will be discussed in the context of a broad range of additional primary and secondary lesions.
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Metadata
Title
Ear and Temporal Bone Pathology: Neural, Sclerosing and Myofibroblastic Lesions
Authors
A. N. Flaman
J. K. Wasserman
D. H. Gravel
B. M. Purgina
Publication date
01-09-2018
Publisher
Springer US
Published in
Head and Neck Pathology / Issue 3/2018
Electronic ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-018-0891-9

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