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12-06-2023 | Dyspnea | Original Article

Relationship between changes in pulmonary function and patient-reported outcomes of lung cancer surgery

Authors: Hideo Ichimura, Keisuke Kobayashi, Masahiko Gosho, Yasuharu Sekine, Kazuto Sugai, Tomoyuki Kawamura, Yusuke Saeki, Hisashi Suzuki, Naohiro Kobayashi, Yukinobu Goto, Yukio Sato

Published in: Surgery Today | Issue 2/2024

Abstract

Purpose

To investigate the relationship between changes in pulmonary function (PF) and patient-reported outcomes (PROs) of lung cancer surgery.

Methods

We recruited 262 patients who underwent lung resection for lung cancer, to evaluate the PROs, using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ)-C30 and the Lung Cancer 13-question supplement (LC13). The patients underwent PF tests and PRO assessments preoperatively (Pre) and 1 year after surgery (Y1). Changes were calculated by subtracting the value at Pre from the value at Y1. We set two cohorts: patients under the ongoing protocol (Cohort 1) and patients who were eligible for lobectomy with clinical stage I lung cancer (Cohort 2).

Results

Cohorts 1 and 2 comprised 206 and 149 patients, respectively. In addition to dyspnea, changes in PF were also correlated with scores for global health status, physical and role function scores, fatigue, nausea and vomiting, pain, and financial difficulties. Absolute correlation coefficient values ranged from 0.149 to 0.311. Improvement of emotional and social function scores was independent of PF. Sublobar resection preserved PF more than lobectomy did. Wedge resection mitigated dyspnea in both cohorts.

Conclusion

The correlation between PF and PROs was found to be weak; therefore, further studies are needed to improve the patient’s postoperative experience.

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Title: Relationship between changes in pulmonary function and patient-reported outcomes of lung cancer surgery
Authors: Hideo Ichimura
Keisuke Kobayashi
Masahiko Gosho
Yasuharu Sekine
Kazuto Sugai
Tomoyuki Kawamura
Yusuke Saeki
Hisashi Suzuki
Naohiro Kobayashi
Yukinobu Goto
Yukio Sato
Publication date: 12-06-2023
Publisher: Springer Nature Singapore
Keywords: Dyspnea
Dyspnea
Lung Cancer
Lung Cancer
Lung Cancer
Lung Cancer Surgery
Published in: Surgery Today / Issue 2/2024
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-023-02716-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Relationship between changes in pulmonary function and patient-reported outcomes of lung cancer surgery

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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