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23-06-2023 | Helicobacter Pylori | Original Article

Remnant gastritis in gastric cancer patients causes loss of muscle mass 6 months after gastrectomy: a retrospective cohort study of Helicobacter pylori infection

Authors: Shiro Fujihata, Shinichi Sakuramoto, Yosuke Morimoto, Kazuaki Matsui, Keiji Nishibeppu, Gen Ebara, Shohei Fujita, Shuichiro Oya, Hirofumi Sugita, Seigi Lee, Yutaka Miyawaki, Hiroshi Sato, Shuji Takiguchi, Keishi Yamashita

Published in: Surgery Today | Issue 2/2024

Abstract

Purpose

In this study, we assessed the relationship between remnant gastritis and muscle mass loss and then investigated the potential relationship between Helicobacter pylori (HP) infection and remnant gastritis and muscle loss.

Methods

We reviewed the medical records of 463 patients who underwent distal gastrectomy between January 2017 and March 2020. Of these patients, 100 with pStage I after laparoscopic surgery were included in this analysis.

Results

A multivariate analysis showed that the total Residue, Gastritis, Bile (RGB) classification score, which indicates the degree of gastritis, was significantly associated with the rate of change (rate of decrease) in the psoas muscle area (PMA) during the first 6 months after surgery (p = 0.014). Propensity score matching was performed according to HP infection, and the rate of change in the PMA and the degree of remnant gastritis in 56 patients were compared. Neither was significantly associated with HP infection.

Conclusions

Remnant gastritis did contribute to psoas muscle mass loss during the initial 6 months after gastrectomy, and HP infection was not significantly associated with either remnant gastritis or psoas muscle mass loss. Nevertheless, the potential for HP eradication to prevent muscle loss and improve the survival prognosis for gastrectomy patients merits further research.

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Title: Remnant gastritis in gastric cancer patients causes loss of muscle mass 6 months after gastrectomy: a retrospective cohort study of Helicobacter pylori infection
Authors: Shiro Fujihata
Shinichi Sakuramoto
Yosuke Morimoto
Kazuaki Matsui
Keiji Nishibeppu
Gen Ebara
Shohei Fujita
Shuichiro Oya
Hirofumi Sugita
Seigi Lee
Yutaka Miyawaki
Hiroshi Sato
Shuji Takiguchi
Keishi Yamashita
Publication date: 23-06-2023
Publisher: Springer Nature Singapore
Keywords: Helicobacter Pylori
Gastritis
Gastrectomy
Gastrectomy
Gastric Cancer
Gastric Cancer
Sarcopenia
Published in: Surgery Today / Issue 2/2024
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-023-02712-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Remnant gastritis in gastric cancer patients causes loss of muscle mass 6 months after gastrectomy: a retrospective cohort study of Helicobacter pylori infection

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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