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Published in: European Radiology 4/2015

01-04-2015 | Pediatric

Dual bolus intravenous contrast injection technique for multiregion paediatric body CT

Authors: Karen E. Thomas, E. H. Mann, N. Padfield, L. Greco, G. BenDavid, A. Alzahrani

Published in: European Radiology | Issue 4/2015

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Abstract

Objectives

Optimal vascular and parenchymal enhancement for multi-region paediatric body computed tomography (CT) has many challenges. A variety of approaches are currently employed, associated with varying image quality and radiation dose implications. We present a dual bolus intravenous (DBI) contrast technique for single-acquisition imaging of the chest, abdomen and pelvis, with evaluation of multi-compartmental vascular enhancement.

Methods

A DBI regime was designed for use with a programmable dual head pump injector. A larger initial bolus (two-thirds volume) is followed by a smaller bolus (one-third volume) before imaging the chest, abdomen and pelvis in a single acquisition, 45–65 seconds from the start of initial injection. Flow rates and second bolus timing were tailored to patient weight and contrast volume, using five weight categories. Multi-compartmental vascular opacification was graded and image quality was assessed in a cohort of 130 patients.

Results

The DBI technique resulted in concordant multi-compartmental (thoracic aortic, pulmonary arterial, abdominal aortic and portal venous) vascular enhancement. Early splenic parenchymal enhancement artefacts and alterations to renal enhancement were observed.

Conclusion

We present a weight-stratified dual bolus intravenous contrast technique to improve image quality in paediatric multi-region body CT.

Key Points

In children, optimal vascular and parenchymal enhancement in multi-region CT is challenging.
A dual bolus contrast technique offers concordant arterial and portal venous opacification.
Adaptation to patient size is achieved by stratification into five weight categories.
Dose penalties of ‘overlap’ and ‘dual phase’ imaging techniques can be avoided.
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Metadata
Title
Dual bolus intravenous contrast injection technique for multiregion paediatric body CT
Authors
Karen E. Thomas
E. H. Mann
N. Padfield
L. Greco
G. BenDavid
A. Alzahrani
Publication date
01-04-2015
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 4/2015
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-014-3501-6

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