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Indian Journal of Pediatrics

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01-10-2016 | Original Article

Distribution and Trends of Human Parainfluenza Viruses in Hospitalised Children

Authors: M. Anjaneya Swamy, Bharti Malhotra, P. V. Janardhan Reddy, Neeraj Kumar, Jitendra Kumar Tiwari, M. L. Gupta

Published in: Indian Journal of Pediatrics | Issue 10/2016

Abstract

Objective

To study the distribution of Human Parainfluenza viruses (HPIV) 1–4 and their trends in children ≤5 y of age, hospitalised at a tertiary care centre, Jaipur and co-infection with other respiratory viruses.

Methods

Nasopharyngeal aspirate and throat swabs were collected and processed for extraction of nucleic acid using automated extraction system and real time RT-PCR was performed using primers and probes specific to HPIV 1–4 and other respiratory viruses on 743 samples.

Results

Total positivity for Parainfluenza viruses 1–4 was found to be 69/743 (9.28 %), of which 50/533 (9.38 %) were boys and 19/210 (9.05 %) girls. Predominance of HPIV- 3 was observed [41/743 (5.52%)] followed by HPIV-1 in 13/743 (1.75%), HPIV-4 in 10/743 (1.34%) and HPIV-2 in 5/743 (0.67%) patients. Maximum positivity was observed in age group 25–36 mo (12.98%) followed by 13–24 mo group (11.96%). HPIVs were found to be circulating round the year and each year. Co-infections with other respiratory viruses were observed in 22/69 (31.88%) of HPIV positive patients.

Conclusions

All the four types of HPIV were found to be circulating in the index population during all the three years, predominantly during post monsoon and winter seasons. HPIV vaccination should be targeted for all types.

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Title: Distribution and Trends of Human Parainfluenza Viruses in Hospitalised Children
Authors: M. Anjaneya Swamy
Bharti Malhotra
P. V. Janardhan Reddy
Neeraj Kumar
Jitendra Kumar Tiwari
M. L. Gupta
Publication date: 01-10-2016
Publisher: Springer India
Published in: Indian Journal of Pediatrics / Issue 10/2016
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI: https://doi.org/10.1007/s12098-016-2139-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Distribution and Trends of Human Parainfluenza Viruses in Hospitalised Children

Abstract

Objective

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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