Published in:
01-12-2008 | Case Report
Digital vasculitis: a late complication of anti-tumour necrosis factor alpha therapy
Published in: Clinical Rheumatology | Issue 12/2008
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Anti-tumour necrosis factor alpha therapy has led to significant advancement in the treatment of rheumatological disease. Rarely, anti-TNFα antagonists have been associated with vasculitis, predominantly cutaneous leukocytoclastic vasculitis. We present the first case of angiographically-confirmed digital vasculitis occurring as a late complication of etanercept therapy. Our case adds to the limited repertoire of case reports of anti-TNFα induced vasculitis and highlights the potential risk of this serious complication occurring up to several years after initiation of these agents.