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01-05-2016 | Breast

Diffusion-weighted imaging of breast tumours at 3 Tesla and 7 Tesla: a comparison

Authors: S. Gruber, L. Minarikova, K. Pinker, O. Zaric, M. Chmelik, B. Strasser, P. Baltzer, T. Helbich, S. Trattnig, W. Bogner

Published in: European Radiology | Issue 5/2016

Abstract

Objectives

To compare bilateral diffusion-weighted MR imaging (DWI) at 3 T and 7 T in the same breast tumour patients.

Methods

Twenty-eight patients were included in this IRB-approved study (mean age 56 ± 16 years). Before contrast-enhanced imaging, bilateral DWI with b = 0 and 850 s/mm² was performed in 2:56 min (3 T) and 3:48 min (7 T), using readout-segmented echo planar imaging (rs-EPI) with a 1.4 × 1.4 mm² (3 T)/0.9 × 0.9 mm² (7 T) in-plane resolution. Apparent diffusion coefficients (ADC), signal-to-noise (SNR) and contrast-to-noise ratios (CNR) were assessed.

Results

Twenty-eight lesions were detected (18 malignant, 10 benign). CNR and SNR were comparable at both field strengths (p > 0.3). Mean ADC values at 7 T were 4–22 % lower than at 3 T (p ≤ 0.03). An ADC threshold of 1.275 × 10⁻³ mm²/s resulted in a diagnostic specificity of 90 % at both field strengths. The sensitivity was 94 % and 100 % at 3 T and 7 T, respectively.

Conclusion

7-T DWI of the breast can be performed with 2.4-fold higher spatial resolution than 3 T, without significant differences in SNR if compared to 3 T.

Key points

• 7 T provides a 2.4-fold higher resolution in breast DWI than 3 T

• 7 T DWI has a high diagnostic accuracy comparable to that at 3 T

• At 7 T malignant lesions had 22 % lower ADC than at 3 T (p < 0.001)

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Title: Diffusion-weighted imaging of breast tumours at 3 Tesla and 7 Tesla: a comparison
Authors: S. Gruber
L. Minarikova
K. Pinker
O. Zaric
M. Chmelik
B. Strasser
P. Baltzer
T. Helbich
S. Trattnig
W. Bogner
Publication date: 01-05-2016
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 5/2016
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-015-3947-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Diffusion-weighted imaging of breast tumours at 3 Tesla and 7 Tesla: a comparison

Abstract

Objectives

Methods

Results

Conclusion

Key points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusion

Key points

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