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European Radiology
Published in: European Radiology 11/2012

01-11-2012 | Musculoskeletal

Advanced MR methods at ultra-high field (7 Tesla) for clinical musculoskeletal applications

Authors: Siegfried Trattnig, Štefan Zbýň, Benjamin Schmitt, Klaus Friedrich, Vladimir Juras, Pavol Szomolanyi, Wolfgang Bogner

Published in: European Radiology | Issue 11/2012

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Abstract

Objectives

This article provides an overview of the initial clinical results of musculoskeletal studies performed at 7 Tesla, with special focus on sodium imaging, new techniques such as chemical exchange saturation transfer (CEST) and T2* imaging, and multinuclear MR spectroscopy.

Methods

Sodium imaging was clinically used at 7 T in the evaluation of patients after cartilage repair procedures because it enables the GAG content to be monitored over time. Sodium imaging and T2* mapping allow insights into the ultra-structural composition of the Achilles tendon and help detect early disease. Chemical exchange saturation transfer was, for the first time, successfully applied in the clinical set-up at 7 T in patients after cartilage repair surgery. The potential of phosphorus MR spectroscopy in muscle was demonstrated in a comparison study between 3 and 7 T, with higher spectral resolution and significantly shorter data acquisition times at 7 T.

Results

These initial clinical studies demonstrate the potential of ultra-high field MR at 7 T, with the advantage of significantly improved sensitivity for other nuclei, such as 23Na (sodium) and 31P (phosphorus).

Conclusions

The application of non-proton imaging and spectroscopy provides new insights into normal and abnormal physiology of musculoskeletal tissues, particularly cartilage, tendons, and muscles.

Key Points

• 7 T magnetic resonance provides significantly improved sensitivity for 23 Na and 31 P.
• Initial clinical studies have now demonstrated ultra-high field MR operating at 7 T.
• 7 T provides new insights into normal and abnormal physiology of musculoskeletal tissues.
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Metadata
Title
Advanced MR methods at ultra-high field (7 Tesla) for clinical musculoskeletal applications
Authors
Siegfried Trattnig
Štefan Zbýň
Benjamin Schmitt
Klaus Friedrich
Vladimir Juras
Pavol Szomolanyi
Wolfgang Bogner
Publication date
01-11-2012
Publisher
Springer-Verlag
Published in
European Radiology / Issue 11/2012
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-012-2508-0

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