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Respiratory Research
Published in: Respiratory Research 1/2016

Open Access 01-12-2016 | Review

Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology

Authors: Nicole E. Speck, Macé M. Schuurmans, Christian Murer, Christian Benden, Lars C. Huber

Published in: Respiratory Research | Issue 1/2016

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Abstract

Diagnosis of acute lung allograft rejection is currently based on transbronchial lung biopsies. Additional methods to detect acute allograft dysfunction derived from plasma and bronchoalveolar lavage samples might facilitate diagnosis and ultimately improve allograft survival. This review article gives an overview of the cell profiles of bronchoalveolar lavage and plasma samples during acute lung allograft rejection. The value of these cells and changes within the pattern of differential cytology to support the diagnosis of acute lung allograft rejection is discussed. Current findings on the topic are highlighted and trends for future research are identified.
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Metadata
Title
Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology
Authors
Nicole E. Speck
Macé M. Schuurmans
Christian Murer
Christian Benden
Lars C. Huber
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Respiratory Research / Issue 1/2016
Electronic ISSN: 1465-993X
DOI
https://doi.org/10.1186/s12931-016-0391-y

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