Diabetologia

Confidence intervals for frequencies of rare alleles

Is the newly suggested fasting plasma glucose cut-off point for the diagnosis of diabetes the right one?

Diabetes epidemiology as a tool to trigger diabetes research and care

P. Z. Zimmet

The impact of a family history of Type II (non-insulin-dependent) diabetes mellitus on the risk of diabetic nephropathy in patients with Type I (insulin-dependent) diabetes mellitus

J. A. Fagerudd, K. J. Pettersson-Fernholm, C. Grönhagen-Riska, P.-H. Groop

Effect of thiazolidinediones on expression of UCP2 and adipocyte markers in human PAZ6 adipocytes

A. Strobel, K. Siquier, V. Zilberfarb, A. D. Strosberg, T. Issad

Exaggerated vasopressin secretion and attenuated osmoregulated thirst in human survivors of hyperosmolar coma

K. McKenna, A. D. Morris, H. Azam, R. W. Newton, P. H. Baylis, C. J. Thompson

Evidence for iNOS-dependent peroxynitrite production in diabetic platelets

M. Tannous, R. A. Rabini, A. Vignini, N. Moretti, P. Fumelli, B. Zielinski, L. Mazzanti, B. Mutus

The RXR agonist LG100268 causes hepatomegaly, improves glycaemic control and decreases cardiovascular risk and cachexia in diabetic mice suffering from pancreatic beta-cell dysfunction

J. M. Lenhard, M. E. Lancaster, M. A. Paulik, J. E. Weiel, J. G. Binz, S. S. Sundseth, B. A. Gaskill, R. M. Lightfoot, H. R. Brown

Spontaneous T-cell proliferation in the non-obese diabetic mouse to a peptide from the unique class II MHC molecule, I-Ag7, which is also protective against the development of autoimmune diabetes

X.-J. Xu, C. Gearon, E. Stevens, D. Vergani, H. Baum, M. Peakman

Glutamate decarboxylase (GAD65) and tyrosine phosphatase-like protein (IA-2) autoantibodies index in a regional population is related to glucose intolerance and body mass index

O. Rolandsson, E. Hägg, C. Hampe, E. P. Sullivan Jr., M. Nilsson, G. Jansson, G. Hallmans, Å. Lernmark

Apoptosis and remodelling of beta cells by paracrine interferon-γ without insulitis in transgenic mice

T. Yamaoka, M. Yano, C. Idehara, T. Yamada, S. Tomonari, M. Moritani, S. Ii, K. Yoshimoto, J. Hata, M. Itakura

Immunological abnormalities in islets at diagnosis paralleled further deterioration of glycaemic control in patients with recent-onset Type I (insulin-dependent) diabetes mellitus

A. Imagawa, T. Hanafusa, N. Itoh, M. Waguri, K. Yamamoto, J. Miyagawa, M. Moriwaki, K. Yamagata, H. Iwahashi, M. Sada, T. Tsuji, S. Tamura, S. Kawata, M. Kuwajima, H. Nakajima, M. Namba, Y. Matsuzawa

Suppression of transforming growth factor beta and vascular endothelial growth factor in diabetic nephropathy in rats by a novel advanced glycation end product inhibitor, OPB-9195

K. Tsuchida, Z. Makita, S. Yamagishi, T. Atsumi, H. Miyoshi, S. Obara, M. Ishida, S. Ishikawa, K. Yasumura, T. Koike

Effect of angiotensin converting enzyme inhibitor or beta blocker on glomerular structural changes in young microalbuminuric patients with Type I (insulin-dependent) diabetes mellitus

S. Rudberg, R. Østerby, H.-J. Bangstad, G. Dahlquist, B. Persson

Increased expression of endothelial antigen PAL-E in human diabetic retinopathy correlates with microvascular leakage

R. O. Schlingemann, P. Hofman, G. F. J. M. Vrensen, H. G. T. Blaauwgeers

Diabetic retinopathy risk correlates with intracellular concentrations of the glycoxidation product Ne-(carboxymethyl) lysine independently of glycohaemoglobin concentrations

H.-P. Hammes, M. Brownlee, J. Lin, E. Schleicher, R. G. Bretzel

Genetic heterogeneity of autoimmune diabetes: age of presentation in adults is influenced by HLA DRB1 and DQB1 genotypes (UKPDS 43)

V. Horton, I. Stratton, G. F. Bottazzo, M. Shattock, I. Mackay, P. Zimmet, S. Manley, R. Holman, R. Turner

Variants in the sulphonylurea receptor gene: association of the exon 16–3t variant with Type II diabetes mellitus in Dutch Caucasians

L. M. ’t Hart, P. de Knijff, J. M. Dekker, R. P. Stolk, G. Nijpels, F. E. E. van der Does, J. B. Ruige, D. E. Grobbee, R. J. Heine, J. A. Maassen

Reflexions on a newly discovered diabetogenic gene, wolframin (WFS1)

K.-D. Gerbitz

Three new mutations in the hepatocyte nuclear factor-1α gene in Japanese subjects with diabetes mellitus: clinical features and functional characterization

I. Yoshiuchi, K. Yamagata, Q. Yang, H. Iwahashi, K. Okita, K. Yamamoto, T. Oue, A. Imagawa, T. Hamaguchi, T. Yamasaki, Y. Horikawa, T. Satoh, H. Nakajima, J. Miyazaki, S. Higashiyama, J. Miyagawa, M. Namba, T. Hanafusa, Y. Matsuzawa

A common mutation of the methylenetetrahydrofolate reductase gene as a risk factor for diabetic nephropathy

Is Trp64Arg polymorphism of β3-adrenergic receptor a clinically useful marker for the predisposition to diabetic nephropathy in Type II diabetic patients?

Reduction of plasma leptin during a short-term fast, an oral glucose tolerance or a meal test can be a misleading bias in clinical studies

Standardization of T-cell assays in Type I diabetes