Diabetologia

Prospects for gene therapy of insulin-dependent diabetes mellitus

S. Efrat

Possible modulation by endothelin-1, nitric oxide, prostaglandin I2 and thromboxane A2 of vasoconstriction induced by an α-agonist in mesenteric arterial bed from diabetic rats

A. Makino, K. Kamata

Depletion of nitric oxide synthase-containing neurons in the diabetic retina: reversal by aminoguanidine

E. Roufail, T. Soulis, E. Boel, M. E. Cooper, S. Rees

Increased expression of endothelial cell nitric oxide synthase (ecNOS) in afferent and glomerular endothelial cells is involved in glomerular hyperfiltration of diabetic nephropathy

H. Sugimoto, K. Shikata, M. Matsuda, M. Kushiro, Y. Hayashi, K. Hiragushi, J. Wada, H. Makino

Advanced glycation endproducts inhibit prostacyclin production and induce plasminogen activator inhibitor-1 in human microvascular endothelial cells

S. Yamagishi, H. Fujimori, H. Yonekura, Y. Yamamoto, H. Yamamoto

Diabetes-induced changes in lens antioxidant status, glucose utilization and energy metabolism: effect of DL-α-lipoic acid

I. Obrosova, X. Cao, D. A. Greene, M. J. Stevens

cAMP regulates nitric oxide production and ouabain sensitive Na+, K+-ATPase activity in SH-SY5Y human neuroblastoma cells

H. Inada, H. Shindo, M. Tawata, T. Onaya

Induction of rat muscle insulin resistance by epinephrine is accompanied by increased interstitial glucose and lactate concentrations

M. Niklasson, A. Holmäng, P. Lönnroth

A search for tyrosine kinase receptors expressed in the rat embryonic pancreas

S. LeBras, P. Czernichow, R. Scharfmann

Increased intestinal glucose absorption and postprandial hyperglycaemia at the early step of glucose intolerance in Otsuka Long-Evans Tokushima Fatty Rats

Y. Fujita, H. Kojima, H. Hidaka, M. Fujimiya, A. Kashiwagi, R. Kikkawa

Inhibition of glucose stimulated insulin secretion by neuropeptide Y is mediated via the Y1 receptor and inhibition of adenylyl cyclase in RIN 5AH rat insulinoma cells

D. G. Morgan, R. N. Kulkarni, J. D. Hurley, Z. L. Wang, R. M. Wang, M. A. Ghatei, A. E. Karlsen, S. R. Bloom, D. M. Smith

Cellular characterization of pituitary adenoma cell line (AtT20 cell) transfected with insulin, glucose transporter type 2 (GLUT2) and glucokinase genes: Insulin secretion in response to physiological concentrations of glucose

S. Motoyoshi, T. Shirotani, E. Araki, K. Sakai, K. Kaneko, H. Motoshima, K. Yoshizato, A. Shirakami, H. Kishikawa, M. Shichiri

Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR ): a meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians

E. H. Hani, P. Boutin, E. Durand, H. Inoue, M. A. Permutt, G. Velho, P. Froguel

Lymphoid Hyperplasia, CD45RBhigh to CD45RBlow T-cell imbalance, and suppression of Type I diabetes mellitus result from TNF blockade in NOD→NOD-scid adoptive T cell transfer

G. R. Brown, M. D. Silva, P. A. Thompson, B. Beutler

The putative role of the hormone-sensitive lipase gene in the pathogenesis of Type II diabetes mellitus and abdominal obesity

M. Klannemark, M. Orho, D. Langin, H. Laurell, C. Holm, S. Reynisdottir, P. Arner, L. Groop

Insulin inhibits inducible nitric oxide synthase in skeletal muscle cells

S. Bédard, B. Marcotte, A. Marette

Mutations in the hepatocyte nuclear factor-1α gene in Caucasian families originally classified as having Type I diabetes

A. M. Møller, L. T. Dalgaard, F. Pociot, J. Nerup, T. Hansen, O. Pedersen

Islet autoimmunity before and after pancreas transplantation in patients with Type I diabetes mellitus

Letters to the editor