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Published in: Digestive Diseases and Sciences 9/2018

01-09-2018 | Correspondence

Depressive Symptoms Predict Anti-tumor Necrosis Factor Therapy Noncompliance and Healthcare Utilization in Patients with Inflammatory Bowel Disease

Authors: Sumedha V. Chablani, Claudia Ramos-Rivers, David G. Binion, Eva Szigethy

Published in: Digestive Diseases and Sciences | Issue 9/2018

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Excerpt

We read with great interest the article by Calloway et al. [1], which retrospectively reviewed treatment data among patients with Crohn’s disease (CD) and ulcerative colitis (UC) at a tertiary inflammatory bowel disease (IBD) clinic. The investigators demonstrated that depressive symptoms (defined as PHQ-9 score ≥ 10) at initiation of anti-tumor necrosis factor therapy were associated with medication noncompliance over a 2-year period, after controlling for age, sex, disease type, and history of psychiatric disease. As the authors argued, these results demonstrate the importance of screening for depression, and suggest a role for implementing psychosocial care to enhance medication compliance, and hopefully improve medical outcomes, in IBD. …
Literature
4.
go back to reference Ananthakrishnan AN, Gainer VS, Perez RG, et al. Psychiatric co-morbidity is associated with increased risk of surgery in Crohn’s disease. Aliment Pharmacol Ther. 2013;37:445–454.CrossRefPubMedPubMedCentral Ananthakrishnan AN, Gainer VS, Perez RG, et al. Psychiatric co-morbidity is associated with increased risk of surgery in Crohn’s disease. Aliment Pharmacol Ther. 2013;37:445–454.CrossRefPubMedPubMedCentral
5.
go back to reference Mittermaier C, Dejaco C, Waldhoer T, et al. Impact of depressive mood on relapse in patients with inflammatory bowel disease: a prospective 18-month follow-up study. Psychosom Med. 2004;66:79–84.CrossRefPubMed Mittermaier C, Dejaco C, Waldhoer T, et al. Impact of depressive mood on relapse in patients with inflammatory bowel disease: a prospective 18-month follow-up study. Psychosom Med. 2004;66:79–84.CrossRefPubMed
7.
go back to reference Szigethy EM, Allen JI, Reiss M, et al. White paper AGA: the impact of mental and psychosocial factors on the care of patients with inflammatory bowel disease. Clin Gastroenterol Hepatol. 2017;15:986–997.CrossRefPubMed Szigethy EM, Allen JI, Reiss M, et al. White paper AGA: the impact of mental and psychosocial factors on the care of patients with inflammatory bowel disease. Clin Gastroenterol Hepatol. 2017;15:986–997.CrossRefPubMed
8.
9.
go back to reference Gracie DJ, Guthrie EA, Hamlin PJ, et al. Bi-directionality of brain–gut interactions in patients with inflammatory bowel disease. Gastroenterology. 2018;154:1635–1646.CrossRefPubMed Gracie DJ, Guthrie EA, Hamlin PJ, et al. Bi-directionality of brain–gut interactions in patients with inflammatory bowel disease. Gastroenterology. 2018;154:1635–1646.CrossRefPubMed
10.
go back to reference Kochar B, Barnes EL, Long MD, et al. Depression is associated with more aggressive inflammatory bowel disease. Am J Gastroenterol. 2018;113:80–85.CrossRefPubMed Kochar B, Barnes EL, Long MD, et al. Depression is associated with more aggressive inflammatory bowel disease. Am J Gastroenterol. 2018;113:80–85.CrossRefPubMed
11.
go back to reference Regueiro M, Click B, Holder D, et al. Constructing an inflammatory bowel disease patient-centered medical home. Clin Gastroenterol Hepatol. 2017;15:1148–1153.CrossRefPubMed Regueiro M, Click B, Holder D, et al. Constructing an inflammatory bowel disease patient-centered medical home. Clin Gastroenterol Hepatol. 2017;15:1148–1153.CrossRefPubMed
Metadata
Title
Depressive Symptoms Predict Anti-tumor Necrosis Factor Therapy Noncompliance and Healthcare Utilization in Patients with Inflammatory Bowel Disease
Authors
Sumedha V. Chablani
Claudia Ramos-Rivers
David G. Binion
Eva Szigethy
Publication date
01-09-2018
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 9/2018
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-018-5194-1

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