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Open Access 01-12-2023 | Denture | Research

Are oral health behaviors associated with metabolic syndrome in the Azar cohort population?

Authors: MohammadAmin Tarighat Esfanjani, Neda Gilani, Ali Tarighat Esfanjani, Amir Mohammad Nourizadeh, Elnaz Faramarzi, Somayeh Hekmatfar

Published in: BMC Oral Health | Issue 1/2023

Abstract

Objective

Considering the rising prevalence of metabolic syndrome (MetS), this study aimed to investigate the relationship between MetS and its components with oral and dental health in the adult population of the Azar cohort.

Methods

In this cross-sectional study oral health care behaviors, DMFT (decayed, missing, and filled teeth) index, and demographic data related to 15,006 patients (5112 in the MetS group and 9894 in the healthy group) of the Azar Cohort population aging from 35 to 70 were collected using appropriate questionnaires. The definition of MetS was based on the National Cholesterol Education Program Adult Treatment Panel III (ATP III) criteria. Then, the risk factors of MetS related to oral health behaviors were determined by proper statistical analysis.

Results

The majority of MetS patients were female (66%) and uneducated (23%) (P < 0.001). In the MetS group, the DMFT index (22.15 ± 8.89) was significantly (p < 0.001) higher (20.81 ± 8.94) than the no MetS group. Not brushing at all was associated with increased odds of MetS (unadjusted OR = 1.12, adjusted OR = 1.18). Flossing less than once a day was associated with increased odds of abdominal obesity (unadjusted OR = 1.17, 95%CI = 1.03–1.32) and hyperglycemia (unadjusted OR = 1.88, 95%CI = 1.61–2.20).

Conclusions

This study showed that in MetS patients of the Azar cohort study, oral hygiene was worse compared to that in the no MetS group. Further studies are suggested to encourage oral hygiene among the general population which has more beneficiary effects than has been known before.

Kamiab N, Kamalabadi YM, Fathollahi MS. DMFT of the First Permanent Molars, dmft and related factors among all First-Grade Primary School students in Rafsanjan Urban Area. J Dent. 2021;22(2):109–17. https://doi.org/10.30476/DENTJODS.2020.85573.1136.CrossRef

Kassebaum N, Bernabé E, Dahiya M, Bhandari B, Murray C, Marcenes W. Global burden of untreated caries: a systematic review and metaregression. J Dent Res. 2015;94(5):650–8. https://doi.org/10.1177/0022034515573272.CrossRefPubMed

Moradi G, Bolbanabad AM, Moinafshar A, Adabi H, Sharafi M, Zareie B. Evaluation of oral health status based on the decayed, missing and filled teeth (DMFT) index. Iran J Public Health. 2019;48(11):2050–7. PMCID: PMC6961190.PubMedPubMedCentral

Chapple I, Genco R. Working group 2 of the joint EFP/AAP workshop. Diabetes and periodontal diseases: consensus report of the Joint EFP. AAP Workshop on periodontitis and systemic diseases J Periodontol. 2013;84(4 Suppl):106–12. https://doi.org/10.1902/jop.2013.1340011.CrossRef

Nibali L, Tatarakis N, Needleman I, Tu Y-K, D’Aiuto F, Rizzo M, Donos N. Association between metabolic syndrome and periodontitis: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2013;98(3):913–20. https://doi.org/10.1210/jc.2012-3552.CrossRefPubMed

Tonetti MS, Van Dyke TE. Periodontitis and atherosclerotic cardiovascular disease: consensus report of the joint EFP/AAP workshop on Periodontitis and systemic Diseases. J Periodontol. 2013;84(Suppl 4):24–S29. https://doi.org/10.1902/jop.2013.1340019.CrossRef

Barrington G, Khan S, Kent K, Brennan DS, Crocombe LA, Bettiol S. Obesity, dietary sugar and dental caries in australian adults. Int Dent J. 2019;69(5):383–91. https://doi.org/10.1111/idj.12480.CrossRefPubMed

Gobin R, Tian D, Liu Q, Wang J. Periodontal diseases and the risk of metabolic syndrome: an updated systematic review and meta-analysis. Front Endocrinol 2020;11:336. doi: https://doi.org/10.3389/fendo.2020.00336.

Abdalla-Aslan R, Findler M, Levin L, Zini A, Shay B, Twig G, Almoznino G. Where periodontitis meets metabolic syndrome—the role of common health‐related risk factors. J Oral Rehabil. 2019;46(7):647–56. https://doi.org/10.1111/joor.12798.CrossRefPubMed

10.

Sigit FS, Tahapary DL, Trompet S, Sartono E, van Willems K, Rosendaal FR, De Mutsert R. The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies. Diabetol Metab Syndr. 2020;12:2. https://doi.org/10.1186/s13098-019-0503-1.CrossRefPubMedPubMedCentral

11.

Solomon S, Mulugeta W. Disease burden and associated risk factors for metabolic syndrome among adults in Ethiopia. BMC Cardiovasc Disord. 2019;19(1):236. https://doi.org/10.1186/s12872-019-1201-5.CrossRefPubMedPubMedCentral

12.

Fatahi A, Doosti-Irani A, Cheraghi Z. Prevalence and incidence of metabolic syndrome in Iran: a systematic review and meta-analysis. Int J Prev Med. 2020;11:64. https://doi.org/10.4103/ijpvm.IJPVM_489_18.CrossRefPubMedPubMedCentral

13.

Saklayen MG. The global epidemic of the metabolic syndrome. Curr Hypertens Rep. 2018 F;20(2):12. doi: https://doi.org/10.1007/s11906-018-0812-z.

14.

Marcaccini AM, Meschiari CA, Sorgi CA, Saraiva MC, de Souza AM, Faccioli LH. etal.Circulating interleukin-6 and high‐sensitivity C‐reactive protein decrease after periodontal therapy in otherwise healthy subjects. J Periodontol. 2009;80(4):594–602. https://doi.org/10.1902/jop.2009.080561.CrossRefPubMed

15.

Kirilmaz B, Asgun F, Alioglu E, Ercan E, Tengiz I, Turk U, et al. High inflammatory activity related to the number of metabolic syndrome components. J Clin Hypertens. 2010;12(2):136–44. https://doi.org/10.1111/j.1751-7176.2009.00229.x.CrossRef

16.

Si J, Lee C, Ko G. Oral microbiota: microbial biomarkers of metabolic syndrome independent of host genetic factors. Front Cell Infect Microbiol. 2017;7:516. https://doi.org/10.3389/fcimb.2017.00516.CrossRefPubMedPubMedCentral

17.

LaMonte MJ, Williams AM, Genco RJ, Andrews CA, Hovey KM, Millen AE, et al. Association between metabolic syndrome and periodontal disease measures in postmenopausal women: the Buffalo OsteoPerio study. J periodontol. 2014;85(11):1489–501. https://doi.org/10.1902/jop.2014.140185.CrossRefPubMed

18.

Nibali L, Donos N, Terranova V, Di Pino A, Di Marca S, Ferrara V, et al. Left ventricular geometry and periodontitis in patients with the metabolic syndrome. Clin Oral Invest. 2019;23:2695–703. https://doi.org/10.1007/s00784-018-2667-8.CrossRef

19.

Rimondini L, Zolfanelli B, Bernardi F, Bez C. Self-preventive oral behavior in an italian university student population. J Clin Periodontol. 2001;28(3):207–11. https://doi.org/10.1034/j.1600-051x.2001.028003207.x.CrossRefPubMed

20.

Tahamtan S, Shirban F, Bagherniya M, Johnston TP, Sahebkar A. The effects of statins on dental and oral health: a review of preclinical and clinical studies. J Transl Med. 2020;18(1):1–42. https://doi.org/10.1186/s12967-020-02326-8.CrossRef

21.

Hamasha AA-H, Aldosari MN, Alturki AM, Aljohani SA, Aljabali IF, Alotibi R. Barrier to access and dental care utilization behavior with related independent variables in the elderly population of Saudi Arabia. J Int Soc Prev Community Dent. 2019;9(4):349–55. https://doi.org/10.4103/jispcd.JISPCD_21_19.CrossRefPubMedPubMedCentral

22.

Poustchi H, Eghtesad S, Kamangar F, Etemadi A, Keshtkar A-A, Hekmatdoost A, et al. Prospective epidemiological research studies in Iran (the PERSIAN Cohort Study): rationale, objectives, and design. Am J Epidemiol. 2018;187(4):647–55. https://doi.org/10.1093/aje/kwx314.CrossRefPubMed

23.

Farhang S, Faramarzi E, Amini Sani N, Poustchi H, Ostadrahimi A, Alizadeh BZ, Somi MH. Cohort profile: the AZAR cohort, a health-oriented research model in areas of major environmental change in Central Asia. Inter J Epidemiol. 2019;48(2):382–382 h. https://doi.org/10.1093/ije/dyy215.CrossRef

24.

Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA. etal.Harmonizing the metabolic syndrome: a joint interim statement of the international diabetes federation task force on epidemiology and prevention; national heart, lung, and blood institute; american heart association; world heart federation; international atherosclerosis society; and international association for the study of obesity. Circulation. 2009;120(16):1640–5. https://doi.org/10.1161/CIRCULATIONAHA.109.192644.CrossRefPubMed

25.

Souza ML, Nascimento GG, González-Chica DA, Peres KG, Peres MA. Counterfactual approach on the effect of metabolic syndrome on tooth loss: a population‐based study. J Periodontol. 2022;93(4):591–602. https://doi.org/10.1002/JPER.21-0175.CrossRefPubMed

26.

Kim Y-H, Kim D-H, Lim KS, Ko B-J, Han B-D, Nam G-E. Oral health behaviors and metabolic syndrome: the 2008–2010 korean National Health and Nutrition Examination Survey. Clin Oral Invest. 2014;18(5):1517–24. https://doi.org/10.1007/s00784-013-1112-2.CrossRef

27.

Kobayashi Y, Niu K, Guan L, Momma H, Guo H, Cui Y, Nagatomi R. Oral health behavior and metabolic syndrome and its components in adults. J Dent Res. 2012;91(5):479–84. https://doi.org/10.1177/00220345124407.CrossRefPubMed

28.

Furuta M, Takeuchi K, Takeshita T, Tanaka A, Suma S, Shinagawa T, et al. Longitudinal associations of toothbrushing with obesity and hyperglycemia. J Epidemiol. 2020;30(12):556–65. https://doi.org/10.2188/jea.JE20190165.CrossRefPubMedPubMedCentral

29.

Isacco CG, Ballini A, De Vito D, Nguyen KC, Cantore S, Bottalico L, et al. Rebalancing the oral microbiota as an efficient tool in endocrine, metabolic and immune disorders. Endocr Metab Immune Disord Drug Targets. 2021;21(5):777–84. https://doi.org/10.2174/1871530320666200729142504.CrossRefPubMed

30.

Minty M, Canceil T, Serino M, Burcelin R, Tercé F, Blasco-Baque V. Oral microbiota-induced periodontitis: a new risk factor of metabolic diseases. Rev Endocr Metab Disord. 2019;20(4):449–59. https://doi.org/10.1007/s11154-019-09526-8.CrossRefPubMed

31.

Latti BR, Kalburge JV, Birajdar SB, Latti RG. Evaluation of relationship between dental caries, diabetes mellitus and oral microbiota in diabetics. J Oral Maxillofac Pathol. 2018;22(2):282. https://doi.org/10.4103/jomfp.JOMFP_163_16.CrossRefPubMedPubMedCentral

32.

Lamont RJ, Koo H, Hajishengallis G. The oral microbiota: dynamic communities and host interactions. Nat Rev Microbiol. 2018;16(12):745–59. https://doi.org/10.1038/s41579-018-0089-x.CrossRefPubMedPubMedCentral

33.

Khazaei S, Keshteli H, Feizi A, Savabi A, Adibi O. P. Epidemiology and risk factors of tooth loss among Iranian adults: findings from a large community-based study. BioMed Res Inter. 2013; 2013. https://doi.org/10.1155/2013/786462.

34.

Teles FR, Teles R, Sachdeo A, Uzel N, Song X, Torresyap G, et al. Comparison of microbial changes in early redeveloping biofilms on natural teeth and dentures. J Periodontol. 2012;83(9):1139–48. https://doi.org/10.1902/jop.2012.110506.CrossRefPubMedPubMedCentral

35.

O’Donnell LE, Robertson D, Nile CJ, Cross LJ, Riggio M, Sherriff A, Bradshaw D, Lambert M, Malcolm J, Buijs MJ. The oral microbiome of denture wearers is influenced by levels of natural dentition. PLoS ONE. 2015;10(9):e0137717. https://doi.org/10.1371/journal.pone.0137717.CrossRefPubMedPubMedCentral

36.

Zhu Y, Hollis JH. Associations between the number of natural teeth and metabolic syndrome in adults. J Clin Periodontol. 2015;42(2):113–20. https://doi.org/10.1111/jcpe.12361.CrossRefPubMed

37.

Ono T, Kato S, Kokubo Y, Hasegawa Y, Kosaka T, Maeda Y et al. Tooth Loss Related with Prevalence of Metabolic Syndrome in a General Urban Japanese Population: The Suita Study. International Journal of Environmental Research and Public Health 2022, 19(11):6441. Int J Environ Res Public Health. 2022;19(11):6441. doi: https://doi.org/10.3390/ijerph19116441.

38.

Saito M, Shimazaki Y, Nonoyama T, Tadokoro Y. Number of teeth, oral self-care, eating speed, and metabolic syndrome in an aged Japanese population. Journal of epidemiology 2019, 29(1):26–32. Epidemiol. 2019;29(1):26–32. doi: https://doi.org/10.2188/jea.JE20170210.

39.

Adachi N, Kobayashi Y. One-year follow-up study on associations between dental caries, periodontitis, and metabolic syndrome. J Oral Sci. 2020;62(1):52–6. https://doi.org/10.2334/josnusd.18-0251.CrossRefPubMed

40.

Iwasaki T, Hirose A, Azuma T, Ohashi T, Watanabe K, Obora A, Deguchi F, Kojima T, Isozaki A, Tomofuji T. Associations between caries experience, dietary habits, and metabolic syndrome in japanese adults. J Oral Sci. 2019;61(2):300–6. https://doi.org/10.2334/josnusd.18-0153.CrossRefPubMed

Title: Are oral health behaviors associated with metabolic syndrome in the Azar cohort population?
Authors: MohammadAmin Tarighat Esfanjani
Neda Gilani
Ali Tarighat Esfanjani
Amir Mohammad Nourizadeh
Elnaz Faramarzi
Somayeh Hekmatfar
Publication date: 01-12-2023
Publisher: BioMed Central
Keywords: Denture
Hyperglycemia
Obesity
Obesity
Published in: BMC Oral Health / Issue 1/2023
Electronic ISSN: 1472-6831
DOI: https://doi.org/10.1186/s12903-023-03003-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Are oral health behaviors associated with metabolic syndrome in the Azar cohort population?

Abstract

Objective

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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