Skip to main content
Top
Published in: BMC Musculoskeletal Disorders 1/2019

Open Access 01-12-2019 | Dementia | Research article

Validation of orthopaedic surgeons’ assessment of cognitive function in patients with acute hip fracture

Authors: Målfrid Holen Kristoffersen, Eva Dybvik, Ole Martin Steihaug, Christoffer Andreas Bartz-Johannesen, Mette Irene Martinsen, Anette Hylen Ranhoff, Lars Birger Engesæter, Jan-Erik Gjertsen

Published in: BMC Musculoskeletal Disorders | Issue 1/2019

Login to get access

Abstract

Background

About one fourth of patients with hip fracture have cognitive impairment. These patients are at higher risk of surgical and medical complications and are often excluded from participating in clinical research. The aim of the present study was to investigate orthopaedic surgeons’ ability to determine the cognitive status of patients with acute hip fracture and to compare the treatment given to patients with and without cognitive impairment.

Methods

The cognitive function of 1474 hip fracture patients reported by the orthopaedic surgeons to the nationwide Norwegian Hip Fracture Register was compared with data registered in quality databases in two hospitals with orthogeriatric service on the same patients. Cognitive function registered in the quality databases was determined either by the short form of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) or by pre-fracture diagnosis of dementia. The information registered in the quality databases was defined as the reference standard. Cognitive function in the Norwegian Hip Fracture Register was reported as: Chronic cognitive impairment? “Yes”, “Uncertain” or “No” by the orthopaedic surgeons. Sensitivity, specificity, negative and positive predictive values for chronic cognitive impairment reported to the Norwegian Hip Fracture Register by the orthopaedic surgeons was calculated.
Baseline data and treatment of hip fractures in patients with and without cognitive impairment in the Norwegian Hip Fracture Register were compared.

Results

Orthopaedic surgeons reported chronic cognitive impairment in 31% of the patients.
Using documented dementia or IQCODE > 4.0 as the reference, this assessment of cognitive impairment by the orthopaedic surgeons had a sensitivity of 69%, a specificity of 90%, a positive predictive value of 78%, and a negative predictive value of 84% compared to information registered in the two hospital quality databases.
There were no differences in type of hip fracture or type of surgical treatment by cognitive function.

Conclusion

The treatment of hip fractures was similar in patients with chronic cognitive impairment and cognitively well-functioning patients. The surgeons had an acceptable ability to identify and report chronic cognitive impairment in the peri-operative period, indicating that the Norwegian Hip Fracture Register is a valuable resource for future registry-based research also on hip fracture patients with chronic cognitive impairment.
Literature
1.
go back to reference Stoen RO, Nordsletten L, Meyer HE, Frihagen JF, Falch JA, Lofthus CM. Hip fracture incidence is decreasing in the high incidence area of Oslo, Norway. Osteoporos Int. 2012;23:2527–34.CrossRef Stoen RO, Nordsletten L, Meyer HE, Frihagen JF, Falch JA, Lofthus CM. Hip fracture incidence is decreasing in the high incidence area of Oslo, Norway. Osteoporos Int. 2012;23:2527–34.CrossRef
2.
go back to reference Gjertsen JE, Fevang JM, Matre K, Vinje T, Engesaeter LB. Clinical outcome after undisplaced femoral neck fractures. Acta Orthop. 2011;82:268–74.CrossRef Gjertsen JE, Fevang JM, Matre K, Vinje T, Engesaeter LB. Clinical outcome after undisplaced femoral neck fractures. Acta Orthop. 2011;82:268–74.CrossRef
3.
go back to reference Seitz DP. Examining the effects of dementia on postoperative outcomes of older adults with hip fractures. Univertity of Toronto: Institute of Health Policy Management and Evaluation; 2014. Seitz DP. Examining the effects of dementia on postoperative outcomes of older adults with hip fractures. Univertity of Toronto: Institute of Health Policy Management and Evaluation; 2014.
4.
go back to reference Seitz DP, Adunuri N, Gill SS, Rochon PA. Prevalence of dementia and cognitive impairment among older adults with hip fractures. J Am Med Dir Assoc. 2011;12:556–64.CrossRef Seitz DP, Adunuri N, Gill SS, Rochon PA. Prevalence of dementia and cognitive impairment among older adults with hip fractures. J Am Med Dir Assoc. 2011;12:556–64.CrossRef
5.
go back to reference Zhao Y, Shen L, Ji HF. Alzheimer’s disease and risk of hip fracture: a meta-analysis study. ScientificWorldJournal. 2012;2012:872173.CrossRef Zhao Y, Shen L, Ji HF. Alzheimer’s disease and risk of hip fracture: a meta-analysis study. ScientificWorldJournal. 2012;2012:872173.CrossRef
6.
go back to reference Tolppanen AM, Lavikainen P, Soininen H, Hartikainen S. Incident hip fractures among community dwelling persons with Alzheimer's disease in a Finnish nationwide register-based cohort. PLoS One. 2013;8:e59124.CrossRef Tolppanen AM, Lavikainen P, Soininen H, Hartikainen S. Incident hip fractures among community dwelling persons with Alzheimer's disease in a Finnish nationwide register-based cohort. PLoS One. 2013;8:e59124.CrossRef
7.
go back to reference Mundi S, Chaudhry H, Bhandari M. Systematic review on the inclusion of patients with cognitive impairment in hip fracture trials: a missed opportunity? Can J Surg. 2014;57:E141–5.CrossRef Mundi S, Chaudhry H, Bhandari M. Systematic review on the inclusion of patients with cognitive impairment in hip fracture trials: a missed opportunity? Can J Surg. 2014;57:E141–5.CrossRef
8.
go back to reference Gjertsen JE, Vinje T, Lie SA, Engesaeter LB, Havelin LI, Furnes O, Fevang JM. Patient satisfaction, pain, and quality of life 4 months after displaced femoral neck fractures: a comparison of 663 fractures treated with internal fixation and 906 with bipolar hemiarthroplasty reported to the Norwegian hip fracture register. Acta Orthop. 2008;79:594–601.CrossRef Gjertsen JE, Vinje T, Lie SA, Engesaeter LB, Havelin LI, Furnes O, Fevang JM. Patient satisfaction, pain, and quality of life 4 months after displaced femoral neck fractures: a comparison of 663 fractures treated with internal fixation and 906 with bipolar hemiarthroplasty reported to the Norwegian hip fracture register. Acta Orthop. 2008;79:594–601.CrossRef
9.
go back to reference Gjertsen JE, Vinje T, Engesaeter LB, Lie SA, Havelin LI, Furnes O, Fevang JM. Internal screw fixation compared with bipolar hemiarthroplasty for treatment of displaced femoral neck fractures in elderly patients. J Bone Joint Surg Am. 2010;92:619–28.CrossRef Gjertsen JE, Vinje T, Engesaeter LB, Lie SA, Havelin LI, Furnes O, Fevang JM. Internal screw fixation compared with bipolar hemiarthroplasty for treatment of displaced femoral neck fractures in elderly patients. J Bone Joint Surg Am. 2010;92:619–28.CrossRef
10.
go back to reference Mukka S, Knutsson B, Krupic F, Sayed-Noor AS. The influence of cognitive status on outcome and walking ability after hemiarthroplasty for femoral neck fracture: a prospective cohort study. Eur J Orthop Surg Traumatol. 2017;27:653–8.CrossRef Mukka S, Knutsson B, Krupic F, Sayed-Noor AS. The influence of cognitive status on outcome and walking ability after hemiarthroplasty for femoral neck fracture: a prospective cohort study. Eur J Orthop Surg Traumatol. 2017;27:653–8.CrossRef
11.
go back to reference Corrada MM, Brookmeyer R, Paganini-Hill A, Berlau D, Kawas CH. Dementia incidence continues to increase with age in the oldest old: the 90+ study. Ann Neurol. 2010;67:114–21.CrossRef Corrada MM, Brookmeyer R, Paganini-Hill A, Berlau D, Kawas CH. Dementia incidence continues to increase with age in the oldest old: the 90+ study. Ann Neurol. 2010;67:114–21.CrossRef
12.
go back to reference Juliebo V, Bjoro K, Krogseth M, Skovlund E, Ranhoff AH, Wyller TB. Risk factors for preoperative and postoperative delirium in elderly patients with hip fracture. J Am Geriatr Soc. 2009;57:1354–61.CrossRef Juliebo V, Bjoro K, Krogseth M, Skovlund E, Ranhoff AH, Wyller TB. Risk factors for preoperative and postoperative delirium in elderly patients with hip fracture. J Am Geriatr Soc. 2009;57:1354–61.CrossRef
13.
go back to reference Krogseth M, Watne LO, Juliebo V, Skovlund E, Engedal K, Frihagen F, Wyller TB. Delirium is a risk factor for further cognitive decline in cognitively impaired hip fracture patients. Arch Gerontol Geriatr. 2016;64:38–44.CrossRef Krogseth M, Watne LO, Juliebo V, Skovlund E, Engedal K, Frihagen F, Wyller TB. Delirium is a risk factor for further cognitive decline in cognitively impaired hip fracture patients. Arch Gerontol Geriatr. 2016;64:38–44.CrossRef
14.
go back to reference Bitch M, Foss N, Kristensen B, Kehlet H. Patogenesis of and management strategies for postoperative delirium after hip fracture: a review. Acta Orthop Scand. 2004;75:378–89.CrossRef Bitch M, Foss N, Kristensen B, Kehlet H. Patogenesis of and management strategies for postoperative delirium after hip fracture: a review. Acta Orthop Scand. 2004;75:378–89.CrossRef
15.
go back to reference Lundstrom M, Edlund A, Bucht G, Karlsson S, Gustafson Y. Dementia after delirium in patients with femoral neck fractures. J Am Geriatr Soc. 2003;51:1002–6.CrossRef Lundstrom M, Edlund A, Bucht G, Karlsson S, Gustafson Y. Dementia after delirium in patients with femoral neck fractures. J Am Geriatr Soc. 2003;51:1002–6.CrossRef
16.
go back to reference Krogseth M, Wyller TB, Engedal K, Juliebo V. Delirium is an important predictor of incident dementia among elderly hip fracture patients. Dement Geriatr Cogn Disord. 2011;31:63–70.CrossRef Krogseth M, Wyller TB, Engedal K, Juliebo V. Delirium is an important predictor of incident dementia among elderly hip fracture patients. Dement Geriatr Cogn Disord. 2011;31:63–70.CrossRef
17.
go back to reference Mosk CA, Mus M, Vroemen JP, van der Ploeg T, Vos DI, Elmans LH, van der Laan L. Dementia and delirium, the outcomes in elderly hip fracture patients. Clin Interv Aging. 2017;12:421–30.CrossRef Mosk CA, Mus M, Vroemen JP, van der Ploeg T, Vos DI, Elmans LH, van der Laan L. Dementia and delirium, the outcomes in elderly hip fracture patients. Clin Interv Aging. 2017;12:421–30.CrossRef
18.
go back to reference Dubljanin-Racpopoc E, Matanovic D, Bumbasirevic M. The impact of cognitive impairment at admission on short-term functional outcome of elderly hip fracture patients. Srp Arh Celok Lek. 2010;138:319–22.CrossRef Dubljanin-Racpopoc E, Matanovic D, Bumbasirevic M. The impact of cognitive impairment at admission on short-term functional outcome of elderly hip fracture patients. Srp Arh Celok Lek. 2010;138:319–22.CrossRef
19.
go back to reference Zerah L, Cohen-Bittan J, Raux M, Meziere A, Tourette C, Neri C, Verny M, Riou B, Khiami F, Boddaert J. Association between cognitive status before surgery and outcomes in elderly patients with hip fracture in a dedicated Orthogeriatric care pathway. J Alzheimers Dis. 2017;56:145–56.CrossRef Zerah L, Cohen-Bittan J, Raux M, Meziere A, Tourette C, Neri C, Verny M, Riou B, Khiami F, Boddaert J. Association between cognitive status before surgery and outcomes in elderly patients with hip fracture in a dedicated Orthogeriatric care pathway. J Alzheimers Dis. 2017;56:145–56.CrossRef
20.
go back to reference Gjertsen JE, Engesaeter LB, Furnes O, Havelin LI, Steindal K, Vinje T, Fevang JM. The Norwegian hip fracture register: experiences after the first 2 years and 15,576 reported operations. Acta Orthop. 2008;79:583–93.CrossRef Gjertsen JE, Engesaeter LB, Furnes O, Havelin LI, Steindal K, Vinje T, Fevang JM. The Norwegian hip fracture register: experiences after the first 2 years and 15,576 reported operations. Acta Orthop. 2008;79:583–93.CrossRef
21.
go back to reference Harrison JK, Fearon P, Noel-Storr AH, McShane R, Stott DJ, Quinn TJ. Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a secondary care setting. Cochrane Database Syst Rev. 2015:Cd010772. Harrison JK, Fearon P, Noel-Storr AH, McShane R, Stott DJ, Quinn TJ. Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a secondary care setting. Cochrane Database Syst Rev. 2015:Cd010772.
22.
go back to reference Quinn TJ, Fearon P, Noel-Storr AH, Young C, McShane R, Stott DJ. Informant questionnaire on cognitive decline in the elderly (IQCODE) for the diagnosis of dementia within community dwelling populations. Cochrane Database Syst Rev. 2014;(4):CD010079. Quinn TJ, Fearon P, Noel-Storr AH, Young C, McShane R, Stott DJ. Informant questionnaire on cognitive decline in the elderly (IQCODE) for the diagnosis of dementia within community dwelling populations. Cochrane Database Syst Rev. 2014;(4):CD010079.
23.
go back to reference Jorm AF. The informant questionnaire on cognitive decline in the elderly (IQCODE): a review. Int Psychogeriatr. 2004;16:275–93.CrossRef Jorm AF. The informant questionnaire on cognitive decline in the elderly (IQCODE): a review. Int Psychogeriatr. 2004;16:275–93.CrossRef
24.
go back to reference Amodeo S, Mainland BJ, Herrmann N, Shulman KI. The times they are a-Changin': clock drawing and prediction of dementia. J Geriatr Psychiatry Neurol. 2015;28:145–55.CrossRef Amodeo S, Mainland BJ, Herrmann N, Shulman KI. The times they are a-Changin': clock drawing and prediction of dementia. J Geriatr Psychiatry Neurol. 2015;28:145–55.CrossRef
25.
go back to reference Naik M, Nygaard HA. Diagnosing dementia -- ICD-10 not so bad after all: a comparison between dementia criteria according to DSM-IV and ICD-10. Int J Geriatr Psychiatry. 2008;23:279–82.CrossRef Naik M, Nygaard HA. Diagnosing dementia -- ICD-10 not so bad after all: a comparison between dementia criteria according to DSM-IV and ICD-10. Int J Geriatr Psychiatry. 2008;23:279–82.CrossRef
26.
go back to reference Prestmo A, Saltvedt I, Helbostad JL, Taraldsen K, Thingstad P, Lydersen S, Sletvold O. Who benefits from orthogeriatric treatment? Results from the Trondheim hip-fracture trial. BMC Geriatr. 2016;16:49.CrossRef Prestmo A, Saltvedt I, Helbostad JL, Taraldsen K, Thingstad P, Lydersen S, Sletvold O. Who benefits from orthogeriatric treatment? Results from the Trondheim hip-fracture trial. BMC Geriatr. 2016;16:49.CrossRef
27.
go back to reference Ranhoff AH, Holvik K, Martinsen MI, Domaas K, Solheim LF. Older hip fracture patients: three groups with different needs. BMC Geriatr. 2010;10:65.CrossRef Ranhoff AH, Holvik K, Martinsen MI, Domaas K, Solheim LF. Older hip fracture patients: three groups with different needs. BMC Geriatr. 2010;10:65.CrossRef
28.
go back to reference Gjertsen JE, Fenstad AM, Leonardsson O, Engesaeter LB, Karrholm J, Furnes O, Garellick G, Rogmark C. Hemiarthroplasties after hip fractures in Norway and Sweden: a collaboration between the Norwegian and Swedish national registries. Hip Int. 2014;24:223–30.CrossRef Gjertsen JE, Fenstad AM, Leonardsson O, Engesaeter LB, Karrholm J, Furnes O, Garellick G, Rogmark C. Hemiarthroplasties after hip fractures in Norway and Sweden: a collaboration between the Norwegian and Swedish national registries. Hip Int. 2014;24:223–30.CrossRef
29.
go back to reference de Vet HC, Mokkink LB, Terwee CB, Hoekstra OS, Knol DL: Clinicians are right not to like Cohen's kappa. Bmj 2013, 346:f2125.CrossRef de Vet HC, Mokkink LB, Terwee CB, Hoekstra OS, Knol DL: Clinicians are right not to like Cohen's kappa. Bmj 2013, 346:f2125.CrossRef
30.
go back to reference Lydersen S. What is the probability of a correct result of a diagnostic test? Tidsskr Nor Laegeforen. 2017;137. Lydersen S. What is the probability of a correct result of a diagnostic test? Tidsskr Nor Laegeforen. 2017;137.
31.
go back to reference Swain DG, Nightingale PG. Evaluation of a shortened version of the abbreviated mental test in a series of elderly patients. Clin Rehabil. 1997;11:243–8.CrossRef Swain DG, Nightingale PG. Evaluation of a shortened version of the abbreviated mental test in a series of elderly patients. Clin Rehabil. 1997;11:243–8.CrossRef
32.
go back to reference Schofield I, Stott DJ, Tolson D, McFadyen A, Monaghan J, Nelson D. Screening for cognitive impairment in older people attending accident and emergency using the 4-item abbreviated mental test. Eur J Emerg Med. 2010;17:340–2.CrossRef Schofield I, Stott DJ, Tolson D, McFadyen A, Monaghan J, Nelson D. Screening for cognitive impairment in older people attending accident and emergency using the 4-item abbreviated mental test. Eur J Emerg Med. 2010;17:340–2.CrossRef
33.
go back to reference Bellelli G, Morandi A, Davis DH, Mazzola P, Turco R, Gentile S, Ryan T, Cash H, Guerini F, Torpilliesi T, et al. Validation of the 4AT, a new instrument for rapid delirium screening: a study in 234 hospitalised older people. Age Ageing. 2014;43:496–502.CrossRef Bellelli G, Morandi A, Davis DH, Mazzola P, Turco R, Gentile S, Ryan T, Cash H, Guerini F, Torpilliesi T, et al. Validation of the 4AT, a new instrument for rapid delirium screening: a study in 234 hospitalised older people. Age Ageing. 2014;43:496–502.CrossRef
34.
go back to reference Mossello E, Tesi F, Di Santo SG, Mazzone A, Torrini M, Cherubini A, Bo M, Musicco M, Bianchetti A, Ferrari A, et al. Recognition of delirium features in clinical practice: data from the "delirium day 2015" National Survey. J Am Geriatr Soc. 2018;66:302–8.CrossRef Mossello E, Tesi F, Di Santo SG, Mazzone A, Torrini M, Cherubini A, Bo M, Musicco M, Bianchetti A, Ferrari A, et al. Recognition of delirium features in clinical practice: data from the "delirium day 2015" National Survey. J Am Geriatr Soc. 2018;66:302–8.CrossRef
35.
go back to reference Norwegian Ortho-Geriatric guidelines on hip fracture treatment [http://legeforeningen.no/PageFiles/329853/Norske%20retningslinjer%20for%20tverrfaglig%20behandling%20av%20hoftebrudd.pdf]. Norwegian Ortho-Geriatric guidelines on hip fracture treatment [http://​legeforeningen.​no/​PageFiles/​329853/​Norske%20retningslinjer%20for%20tverrfaglig%20behandling%20av%20hoftebrudd.pdf].
Metadata
Title
Validation of orthopaedic surgeons’ assessment of cognitive function in patients with acute hip fracture
Authors
Målfrid Holen Kristoffersen
Eva Dybvik
Ole Martin Steihaug
Christoffer Andreas Bartz-Johannesen
Mette Irene Martinsen
Anette Hylen Ranhoff
Lars Birger Engesæter
Jan-Erik Gjertsen
Publication date
01-12-2019
Publisher
BioMed Central
Keywords
Dementia
Dementia
Published in
BMC Musculoskeletal Disorders / Issue 1/2019
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-019-2633-x

Other articles of this Issue 1/2019

BMC Musculoskeletal Disorders 1/2019 Go to the issue