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European Archives of Oto-Rhino-Laryngology

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Open Access 26-10-2023 | Cystic Fibrosis | Rhinology

The development of paranasal sinuses in patients with cystic fibrosis: sinuses volume analysis

Authors: Agata Kaluzna-Mlynarczyk, Beata Pucher, Jakub Sroczynski, Michal Kotowski, Katarzyna Jonczyk-Potoczna, Jarosław Szydlowski

Published in: European Archives of Oto-Rhino-Laryngology | Issue 2/2024

Abstract

Background

Cystic fibrosis (CF) is a severe systemic disease that affects many aspects of patients’ lives. It is known that the progression of the disease adversely affects lower and upper airways including the paranasal sinuses. However, its impact on sinus development in the pediatric population is not fully examined. The purpose of this study was to evaluate the development of the paranasal sinuses in a pediatric population with CF and compare it to a control group consisting of healthy children.

Methods

The results of computed tomography (CT) scans of children with the disease and the control group were evaluated. The study included 114 CT images of children in the study group and 126 images of healthy children aged 0–18 years. The volumes of maxillary, frontal, and sphenoid sinuses were analyzed. The obtained results were compared with those of the control group and analyzed statistically.

Results

The volume and the development of the paranasal sinuses in both groups increased with age, but statistically significant differences were found between the study and the control group.

Conclusions

The obtained results provide valuable knowledge regarding the impact of the CF on sinuses development. Also, they may be important in understanding the progression of the disease and its influence on the quality and length of life of patients. The results may contribute to enhanced diagnostics and have implications for improving therapy for patients with chronic sinusitis associated with CF.

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Title: The development of paranasal sinuses in patients with cystic fibrosis: sinuses volume analysis
Authors: Agata Kaluzna-Mlynarczyk
Beata Pucher
Jakub Sroczynski
Michal Kotowski
Katarzyna Jonczyk-Potoczna
Jarosław Szydlowski
Publication date: 26-10-2023
Publisher: Springer Berlin Heidelberg
Keywords: Cystic Fibrosis
Cystic Fibrosis
Computed Tomography
Computed Tomography
Published in: European Archives of Oto-Rhino-Laryngology / Issue 2/2024
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-023-08236-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The development of paranasal sinuses in patients with cystic fibrosis: sinuses volume analysis

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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