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Indian Journal of Pediatrics
Published in: Indian Journal of Pediatrics 4/2024

19-10-2023 | Cystic Fibrosis | Scientific Letter

Rare Central Nervous System Infection in an Infant with Immunodeficiency

Authors: Ketan Kumar, Richa Singh, Mukta Mantan

Published in: Indian Journal of Pediatrics | Issue 4/2024

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Excerpt

To the Editor: A 45-d-old boy was referred to us with a persistent central nervous system (CNS) infection. Born to second degree consanguineous parents, the child had received treatment for early onset sepsis and pneumonia, followed by poor weight gain at home. On day 24, he was re-admitted with apnea and cyanosis. Cerebrospinal fluid (CSF) examination suggested meningitis. Blood and CSF cultures grew Candida pelliculosa and Burkholderia cepacia respectively. There was ventriculomegaly with CSF ooze and diffuse meningeal enhancement on neuroimaging. At presentation, the child had no CNS deficits. …
Literature
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Winkelstein JA, Marino MC, Johnston RB Jr, et al. Chronic granulomatous disease. Report on a national registry of 368 patients. Med (Baltim). 2000;79:155–69.CrossRef
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Rawat A, Vignesh P, Sudhakar M, et al. Clinical, immunological, and molecular profile of chronic granulomatous disease: a multi-centric study of 236 patients from India. Front Immunol. 2021;12:625320.CrossRefPubMedPubMedCentral
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Patra S, Bhat YR, Lewis LE, et al. Burkholderia cepacia sepsis among neonates. Indian J Pediatr. 2014;81:1233–6.CrossRefPubMed
Metadata
Title
Rare Central Nervous System Infection in an Infant with Immunodeficiency
Authors
Ketan Kumar
Richa Singh
Mukta Mantan
Publication date
19-10-2023
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 4/2024
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-023-04886-1

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