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Published in: World Journal of Surgical Oncology 1/2011

Open Access 01-12-2011 | Case report

Cystic cavernous malformation of the cerebellopontine angle: Case report and literature review

Authors: Haiyan Huang, Kan Xu, Limei Qu, Ye Li, Jinlu Yu

Published in: World Journal of Surgical Oncology | Issue 1/2011

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Abstract

Background

Cavernous malformations (CMs) in the cerebellopontine angle (CPA) are rare, and most of such CMs reported to date are solid and extend from the internal auditory canal into the CPA. In contrast, cystic CMs that arise in the CPA and do not involve the internal auditory canal and dura of the skull base are extremely rare.

Case presentation

A 50-year-old man presented with vertigo and progressive hearing loss in the right ear. MRI examination revealed a lesion in the CPA with solid and cystic components. Surgery was performed. Well-circumscribed adhesion to cranial nerves, the cerebellum, or the brain stem was noted during surgery. The lesion was totally resected. Pathological examination suggested the lesion to be a CM. At 1-year follow-up, the symptoms at presentation had resolved and no complications had occurred.

Conclusion

Although cystic CMs of the CPA have no established imaging features, a diagnosis of CMs may be suspected when a cystic lesion is present in the CPA and does not involve internal acoustic meatus or dura mater of the skull base. Skillful microsurgical techniques and monitoring of cranial nerves will secure good outcomes for patients with cystic CMs in the CPA.
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Literature
1.
go back to reference Bertalanffy H, Benes L, Miyazawa T, Alberti O, Siegel AM, Sure U: Cerebral cavernomas in the adult. Review of the literature and analysis of 72 surgically treated patients. Neurosurg Rev. 2002, 25: 1-53. 10.1007/s101430100179.CrossRefPubMed Bertalanffy H, Benes L, Miyazawa T, Alberti O, Siegel AM, Sure U: Cerebral cavernomas in the adult. Review of the literature and analysis of 72 surgically treated patients. Neurosurg Rev. 2002, 25: 1-53. 10.1007/s101430100179.CrossRefPubMed
2.
go back to reference Batra S, Lin D, Recinos PF, Zhang J, Rigamonti D: Medscape: Cavernous malformations: natural history, diagnosis and treatment. Nat Rev Neurol. 2009, 5: 659-70. 10.1038/nrneurol.2009.177.CrossRefPubMed Batra S, Lin D, Recinos PF, Zhang J, Rigamonti D: Medscape: Cavernous malformations: natural history, diagnosis and treatment. Nat Rev Neurol. 2009, 5: 659-70. 10.1038/nrneurol.2009.177.CrossRefPubMed
3.
go back to reference Martin NA, Vinters H: Pathology and grading of intracranial vascular malformation. Edited by: Barrow DL. 1990, Intracranial Vascular Malformation. Park Ridge, IL: AANS, 1-30. Martin NA, Vinters H: Pathology and grading of intracranial vascular malformation. Edited by: Barrow DL. 1990, Intracranial Vascular Malformation. Park Ridge, IL: AANS, 1-30.
4.
go back to reference Engh JA, Kostov D, St Martin MB, Yeaney G, Rothfus W, Hirsch B, Kassam AB: Cavernous malformation tumors: a case study and review of the literature. Otol Neurotol. 2010, 31: 294-8. 10.1097/MAO.0b013e3181c34bf2.CrossRefPubMed Engh JA, Kostov D, St Martin MB, Yeaney G, Rothfus W, Hirsch B, Kassam AB: Cavernous malformation tumors: a case study and review of the literature. Otol Neurotol. 2010, 31: 294-8. 10.1097/MAO.0b013e3181c34bf2.CrossRefPubMed
5.
go back to reference Iplikçioğlu AC, Benli K, Bertan V, Ruacan S: Cystic cavernous hemangioma of the cerebellopontine angle: case report. Neurosurgery. 1986, 19: 641-2.CrossRefPubMed Iplikçioğlu AC, Benli K, Bertan V, Ruacan S: Cystic cavernous hemangioma of the cerebellopontine angle: case report. Neurosurgery. 1986, 19: 641-2.CrossRefPubMed
6.
go back to reference Brunori A, Chiappetta F: Cystic extra-axial cavernoma of the cerebellopontine angle. Surg Neurol. 1996, 46: 475-6.4. 10.1016/S0090-3019(96)00153-X.CrossRefPubMed Brunori A, Chiappetta F: Cystic extra-axial cavernoma of the cerebellopontine angle. Surg Neurol. 1996, 46: 475-6.4. 10.1016/S0090-3019(96)00153-X.CrossRefPubMed
7.
go back to reference Vajramani GV, Devi BI, Hegde T, Srikanth SG, Shankar SK: Cystic cavernous malformation of the cerebellopontine angle. Clin Neurol Neurosurg. 1998, 100: 133-7. 10.1016/S0303-8467(98)00016-X.CrossRefPubMed Vajramani GV, Devi BI, Hegde T, Srikanth SG, Shankar SK: Cystic cavernous malformation of the cerebellopontine angle. Clin Neurol Neurosurg. 1998, 100: 133-7. 10.1016/S0303-8467(98)00016-X.CrossRefPubMed
8.
go back to reference Stevenson CB, Johnson MD, Thompson RC: Cystic cavernous malformation of the cerebellopontine angle. Case illustration. J Neurosurg. 2005, 103: 931-PubMed Stevenson CB, Johnson MD, Thompson RC: Cystic cavernous malformation of the cerebellopontine angle. Case illustration. J Neurosurg. 2005, 103: 931-PubMed
9.
go back to reference Ohba S, Shimizu K, Shibao S, Nakagawa T, Murakami H: Cystic cavernous angiomas. Neurosurg Rev. 2010, 33: 395-400. 10.1007/s10143-010-0245-x.CrossRefPubMed Ohba S, Shimizu K, Shibao S, Nakagawa T, Murakami H: Cystic cavernous angiomas. Neurosurg Rev. 2010, 33: 395-400. 10.1007/s10143-010-0245-x.CrossRefPubMed
10.
go back to reference Batra S, Lin D, Recinos PF, Zhang J, Rigamonti D: Medscape: Cavernous malformations: natural history, diagnosis and treatment. Nat Rev Neurol. 2009, 5: 659-70. 10.1038/nrneurol.2009.177.CrossRefPubMed Batra S, Lin D, Recinos PF, Zhang J, Rigamonti D: Medscape: Cavernous malformations: natural history, diagnosis and treatment. Nat Rev Neurol. 2009, 5: 659-70. 10.1038/nrneurol.2009.177.CrossRefPubMed
11.
go back to reference Sato K, Kubota T: Large calcified cystic cavernous angioma in the thalamus--case report. Neurol Med Chir (Tokyo). 1995, 35: 100-3. 10.2176/nmc.35.100.CrossRef Sato K, Kubota T: Large calcified cystic cavernous angioma in the thalamus--case report. Neurol Med Chir (Tokyo). 1995, 35: 100-3. 10.2176/nmc.35.100.CrossRef
12.
go back to reference Hatashita S, Miyajima M, Koga N: Cystic cavernous angioma--case report. Neurol Med Chir (Tokyo). 1991, 31: 414-6. 10.2176/nmc.31.414.CrossRef Hatashita S, Miyajima M, Koga N: Cystic cavernous angioma--case report. Neurol Med Chir (Tokyo). 1991, 31: 414-6. 10.2176/nmc.31.414.CrossRef
13.
go back to reference Pinker K, Stavrou I, Knosp E, Trattnig S: Are cerebral cavernomas truly nonenhancing lesions and thereby distinguishable from arteriovenous malformations?. MRI findings and histopathological correlation. Magn Reson Imaging. 2006, 24: 631-7.CrossRefPubMed Pinker K, Stavrou I, Knosp E, Trattnig S: Are cerebral cavernomas truly nonenhancing lesions and thereby distinguishable from arteriovenous malformations?. MRI findings and histopathological correlation. Magn Reson Imaging. 2006, 24: 631-7.CrossRefPubMed
14.
go back to reference Hauck EF, Barnett SL, White JA, Samson D: Symptomatic brainstem cavernomas. Neurosurgery. 2009, 64: 61-70. 10.1227/01.NEU.0000335158.11692.53.CrossRefPubMed Hauck EF, Barnett SL, White JA, Samson D: Symptomatic brainstem cavernomas. Neurosurgery. 2009, 64: 61-70. 10.1227/01.NEU.0000335158.11692.53.CrossRefPubMed
15.
go back to reference Yagi K, Kageji T, Nagahiro S, Murayama Y: Multiple cystic cavernous angiomas associated with hemorrhage. Acta Neurochir (Wien). 2005, 147: 201-3. 10.1007/s00701-004-0381-6.CrossRef Yagi K, Kageji T, Nagahiro S, Murayama Y: Multiple cystic cavernous angiomas associated with hemorrhage. Acta Neurochir (Wien). 2005, 147: 201-3. 10.1007/s00701-004-0381-6.CrossRef
16.
go back to reference Tomlinson FH, Houser OW, Scheithauer BW, Sundt TM, Okazaki H, Parisi JE: Angiographically occult vascular malformations: a correlative study of features on magnetic resonance imaging and histological examination. Neurosurgery. 1994, 34: 792-9. 10.1227/00006123-199405000-00002.CrossRefPubMed Tomlinson FH, Houser OW, Scheithauer BW, Sundt TM, Okazaki H, Parisi JE: Angiographically occult vascular malformations: a correlative study of features on magnetic resonance imaging and histological examination. Neurosurgery. 1994, 34: 792-9. 10.1227/00006123-199405000-00002.CrossRefPubMed
17.
go back to reference Pozzati E, Acciarri N, Tognetti F, Marliani F, Giangaspero F: Growth, subsequent bleeding, and de novo appearance of cerebral cavernous angiomas. Neurosurgery. 1996, 38: 662-9. 10.1097/00006123-199604000-00006.CrossRefPubMed Pozzati E, Acciarri N, Tognetti F, Marliani F, Giangaspero F: Growth, subsequent bleeding, and de novo appearance of cerebral cavernous angiomas. Neurosurgery. 1996, 38: 662-9. 10.1097/00006123-199604000-00006.CrossRefPubMed
Metadata
Title
Cystic cavernous malformation of the cerebellopontine angle: Case report and literature review
Authors
Haiyan Huang
Kan Xu
Limei Qu
Ye Li
Jinlu Yu
Publication date
01-12-2011
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2011
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-9-36

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