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Clinical Reviews in Allergy & Immunology

Published in:

01-06-2012

Cutting-edge Issues in Autoimmunity and Allergy of the Digestive System

Author: Carlo Selmi

Published in: Clinical Reviews in Allergy & Immunology | Issue 3/2012

Abstract

Autoimmunity and allergy involving the digestive system may be considered as paradigmatic for numerous common themes of complex diseases secondary to tolerance breakdown. Among gastrointestinal autoimmune diseases, for example, we encounter diseases in which a clear environmental trigger is identified (i.e., celiac disease), serum autoantibodies are most specific (i.e., primary biliary cirrhosis), or in which the disease pathophysiology is clearly understood (i.e., autoimmune gastritis). Similarly, it is intriguing that the gastrointestinal tract and the liver circulation represent the crucial environment for the development of immune tolerance. This issue is dedicated to the discussion of recent concepts while identifying two major common issues, i.e., the need for serum biomarkers and the role of vitamin D. Other common themes characterize the etiology and effector mechanisms of these and other autoimmune diseases and are discussed in each cutting-edge overview.

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Title: Cutting-edge Issues in Autoimmunity and Allergy of the Digestive System
Author: Carlo Selmi
Publication date: 01-06-2012
Publisher: Humana Press Inc
Published in: Clinical Reviews in Allergy & Immunology / Issue 3/2012
Print ISSN: 1080-0549
Electronic ISSN: 1559-0267
DOI: https://doi.org/10.1007/s12016-012-8311-5

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Other articles of this Issue 3/2012

A Novel Algorithm for the Diagnosis of Celiac Disease and a Comprehensive Review of Celiac Disease Diagnostics

A Contemporary Review of Seafood Allergy

The Diagnostic and Clinical Significance of Anti-Muscarinic Receptor Autoantibodies

Cutting Edge Issues in Autoimmune Hepatitis

Overcoming a “Probable” Diagnosis in Antimitochondrial Antibody Negative Primary Biliary Cirrhosis: Study of 100 Sera and Review of the Literature

Hypovitaminosis D as Predisposing Factor for Atrophic Type A Gastritis: a Case–Control Study and Review of the Literature on the Interaction of Vitamin D with the Immune System

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Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

At a glance: The STEP trials