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01-04-2018 | Review

Current and future challenges in HCV: insights from an Italian experts panel

Authors: Massimo Andreoni, Sergio Babudieri, Savino Bruno, Massimo Colombo, Anna L. Zignego, Vito Di Marco, Giovanni Di Perri, Carlo F. Perno, Massimo Puoti, Gloria Taliani, Erica Villa, Antonio Craxì

Published in: Infection | Issue 2/2018

Abstract

Background

The recent availability of direct acting antiviral drugs (DAAs) has drastically changed hepatitis C virus (HCV) treatment scenarios, due to the exceedingly high rates of sustained virological response (SVR) and excellent tolerability allowing for treatment at all disease stages.

Methods

A panel of Italian experts was convened twice, in November 2016 and January 2017, to provide further support on some open issues and provide guidance for personalized HCV care, also in light of forthcoming regimens.

Results and conclusions

Treatment recommendations issued by international and national liver societies to guide clinicians in the management of HCV infection are constantly updated due to accumulating new data. Such recommendations may not be applicable to all healthcare settings for a variety of reasons. Moreover, some gaps still remain and the spectrum of patients to be treated is also evolving.

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Title: Current and future challenges in HCV: insights from an Italian experts panel
Authors: Massimo Andreoni
Sergio Babudieri
Savino Bruno
Massimo Colombo
Anna L. Zignego
Vito Di Marco
Giovanni Di Perri
Carlo F. Perno
Massimo Puoti
Gloria Taliani
Erica Villa
Antonio Craxì
Publication date: 01-04-2018
Publisher: Springer Berlin Heidelberg
Published in: Infection / Issue 2/2018
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI: https://doi.org/10.1007/s15010-017-1093-1

Obesity Clinical Trial Summary

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A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

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STEP AAG HeroTeaserCollection image/© Tarek / Generated with AI / Stock.adobe.com, ACC 2024 Pediatric and Congenital Heart Disease: Year in Review/© 2024 American College of Cardiology, ACC 2024 Pulmonary Vascular Disease: Year in Review/© 2024 American College of Cardiology, ACC 2024 Valvular Heart Disease: Year in Review/© 2024 American College of Cardiology, ACC 2024 HF and Cardiomyopathies: Year in Review/© 2024 American College of Cardiology, Woman out walking/© Seventyfour / stock.adobe.com (symbolic image with model), Woman checking smartwatch /© saltdium / stock.adobe.com (symbolic image with model), Cardiac catheterization/© Damian / stock.adobe.com

At a glance: The STEP trials

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Abstract

Background

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