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Published in: Abdominal Radiology 4/2017

01-04-2017

CT angiography in the setting of suspected acute mesenteric ischemia: prevalence of ischemic and alternative diagnoses

Authors: Frank Oliver Henes, Perry J. Pickhardt, Andrzej Herzyk, Scott J. Lee, Utaroh Motosugi, Thorsten Derlin, Meghan G. Lubner, Gerhard Adam, Gerhard Schön, Peter Bannas

Published in: Abdominal Radiology | Issue 4/2017

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Abstract

Purpose

The purpose of the study was to determine the prevalence of ischemic and alternative diagnoses and the diagnostic accuracy of CT angiography (CTA) in the setting of suspected acute mesenteric ischemia (AMI).

Material and methods

We included 959 patients undergoing CTA for the evaluation of suspected AMI. The final clinical diagnosis was used to determine the prevalence of ischemic and alternative diagnoses and to calculate the diagnostic accuracy of CTA. Prevalence of diagnoses by age, sex, and admission status was compared using Cochran–Armitage and χ 2 tests.

Results

Prevalence was 18.8% (180/959) for AMI and 61.2% (587/959) for specific alternative diagnoses. In the remaining 20.0% (192/959), no clear clinical diagnosis was established. The most frequent alternative diagnoses were small-bowel obstruction (10.4%; 61/587), infectious colitis (8.7%; 51/587), pneumonia (6.5%; 38/587), cholecystitis (6.1%; 36/587), and diverticulitis (5.6%; 33/587). Prevalence of specific alternative diagnoses varied significantly according to both age (p < .013) and admissions status (p < 0.001). CTA had a sensitivity and specificity for diagnosing AMI of 89.4%/99.5% and for alternative diagnoses of 86.7%/96.9%, respectively.

Conclusion

In the setting of suspected AMI, the prevalence of ischemic and alternative diagnoses varies significantly by age, sex, and admission status. CTA provides for rapid and non-invasive assessment of ischemic and alternative diagnoses with high diagnostic accuracy.
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Metadata
Title
CT angiography in the setting of suspected acute mesenteric ischemia: prevalence of ischemic and alternative diagnoses
Authors
Frank Oliver Henes
Perry J. Pickhardt
Andrzej Herzyk
Scott J. Lee
Utaroh Motosugi
Thorsten Derlin
Meghan G. Lubner
Gerhard Adam
Gerhard Schön
Peter Bannas
Publication date
01-04-2017
Publisher
Springer US
Published in
Abdominal Radiology / Issue 4/2017
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-016-0988-0

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