Skip to main content
Top
Published in: Child's Nervous System 2/2013

01-02-2013 | Original Paper

CSF diversion in refractory idiopathic intracranial hypertension: single-centre experience and review of efficacy

Authors: Georgios Niotakis, Dionysios Grigoratos, Chris Chandler, Danny Morrison, Ming Lim

Published in: Child's Nervous System | Issue 2/2013

Login to get access

Abstract

Purpose

The current surgical management strategies for refractory cases of idiopathic intracranial hypertension (IIH) remain unresolved. We evaluated the outcome of our paediatric patients who were offered a CSF diversion procedure in order to control their symptoms.

Methods

We retrospectively reviewed the medical notes of the patients under 16 years of age, who presented in our centre from 2005 to 2010, with a confirmed diagnosis of IIH, and ultimately had a lumboperitoneal shunt (LPS). We describe their immediate postoperative course, shunt-related complications and recent outcome.

Results

Seven patients presented at a mean age of 8.7 years. Two presented with significant visual loss and had a shunt acutely; the remaining five presented with headaches and were shunted within 2 years. In the immediate postoperative period two patients experienced low-pressure symptoms. All patients required shunt revisions; in total 15 revisions took place, mainly secondary to symptomatic overdrainage or obstruction. After a mean follow-up of 26 months, two patients have diminished visual acuity at least on one side; only one patient became headache-free, despite resolution of the CSF pressure post diversion in four out of the six remaining patients.

Conclusions

All patients required shunt revisions and 6/7 (85.7 %) had persisting headaches at their last follow-up. It is apparent that once functional, the LPS seems adequate to lower the CSF pressure but not effective in eliminating symptoms.
Literature
1.
go back to reference Friedman DI, Jacobson DM (2002) Diagnostic criteria for idiopathic intracranial hypertension. Neurology 59(10):1492–1495PubMedCrossRef Friedman DI, Jacobson DM (2002) Diagnostic criteria for idiopathic intracranial hypertension. Neurology 59(10):1492–1495PubMedCrossRef
2.
go back to reference Lueck CJ, McIlwaine GG (2005) Interventions for Idiopathic Intracranial Hypertension. Cochrane Database Syst Rev 20 (3):CD003434 Lueck CJ, McIlwaine GG (2005) Interventions for Idiopathic Intracranial Hypertension. Cochrane Database Syst Rev 20 (3):CD003434
3.
go back to reference Ragwala LM, Liu GT (2007) Pediatric idiopathic intracranial hypertension. Surv Ophthalmol 52(6):597–617CrossRef Ragwala LM, Liu GT (2007) Pediatric idiopathic intracranial hypertension. Surv Ophthalmol 52(6):597–617CrossRef
4.
go back to reference Avery RA, Shah SS, Licht DJ, Seiden JA (2010) Reference range for cerebrospinal fluid opening pressure in children. N Engl J Med 363(9):891–893PubMedCrossRef Avery RA, Shah SS, Licht DJ, Seiden JA (2010) Reference range for cerebrospinal fluid opening pressure in children. N Engl J Med 363(9):891–893PubMedCrossRef
5.
go back to reference Higgins JNP, Cousins C, Owler BK, Sarkies N, Pickard JD (2003) Idiopathic intracranial hypertension: 12 cases treated by venous sinus stenting. J Neurol Neurosurg Psychiatry 74:1662–1666PubMedCrossRef Higgins JNP, Cousins C, Owler BK, Sarkies N, Pickard JD (2003) Idiopathic intracranial hypertension: 12 cases treated by venous sinus stenting. J Neurol Neurosurg Psychiatry 74:1662–1666PubMedCrossRef
6.
go back to reference Brazis PW (2008) Clinical review: the surgical treatment of idiopathic pseudotumor cerebri (idiopathic intracranial hypertension). Cephalalgia 28:1361–1373PubMedCrossRef Brazis PW (2008) Clinical review: the surgical treatment of idiopathic pseudotumor cerebri (idiopathic intracranial hypertension). Cephalalgia 28:1361–1373PubMedCrossRef
7.
go back to reference McGirt MJ, Woodworth G, Thomas G, Miller N, Williams M, Rigamonti D (2004) Cerebrospinal fluid shunt placement for pseudotumor cerebri-associated intracrable headache: predictors of treatment response and an analysis of long term outcomes. J Neurosurg 101:627–632PubMedCrossRef McGirt MJ, Woodworth G, Thomas G, Miller N, Williams M, Rigamonti D (2004) Cerebrospinal fluid shunt placement for pseudotumor cerebri-associated intracrable headache: predictors of treatment response and an analysis of long term outcomes. J Neurosurg 101:627–632PubMedCrossRef
8.
go back to reference Abubaker K, Ali Z, Raza K, Bolger C, Rawluk D, O'Brien D (2011) Idiopathic intracranial hypertension: lumboperitoneal shunts versus ventriculoperitoneal shunts—case series and literature review. Br J Neurosurg 25(1):94–99PubMedCrossRef Abubaker K, Ali Z, Raza K, Bolger C, Rawluk D, O'Brien D (2011) Idiopathic intracranial hypertension: lumboperitoneal shunts versus ventriculoperitoneal shunts—case series and literature review. Br J Neurosurg 25(1):94–99PubMedCrossRef
9.
go back to reference Eggenberg ER, Miller NR, Vitale S (1996) Lumboperitoneal shunt for the treatment of pseudotumor cerebri. Neurology 46:1524–1530CrossRef Eggenberg ER, Miller NR, Vitale S (1996) Lumboperitoneal shunt for the treatment of pseudotumor cerebri. Neurology 46:1524–1530CrossRef
10.
go back to reference Nadkarni TD, Rekate HL, Wallace D (2008) Concurrent use of a lumboperitoneal shunt with programmable valve and ventricular access device in the treatment of pseudotumor cerebri: review of 40 cases. J Neurosurg Pediatrics 2:19–24CrossRef Nadkarni TD, Rekate HL, Wallace D (2008) Concurrent use of a lumboperitoneal shunt with programmable valve and ventricular access device in the treatment of pseudotumor cerebri: review of 40 cases. J Neurosurg Pediatrics 2:19–24CrossRef
11.
go back to reference Standridge SM (2010) Idiopathic intracranial hypertension in children: a review and algorithm. Pediatr Neurol 43:377–390PubMedCrossRef Standridge SM (2010) Idiopathic intracranial hypertension in children: a review and algorithm. Pediatr Neurol 43:377–390PubMedCrossRef
12.
go back to reference Thambisetty M, Lavin PJ, Newman NJ, Biousse V (2007) Fulminant idiopathic intracranial hypertension. Neurology 68:229–232PubMedCrossRef Thambisetty M, Lavin PJ, Newman NJ, Biousse V (2007) Fulminant idiopathic intracranial hypertension. Neurology 68:229–232PubMedCrossRef
13.
go back to reference Ahmed RM, Wilkinson M, Parker GD, Thurtell MJ, Macdonald J, McCluskey PJ, Allan R, Dunne V, Hanlon M, Owler BK, Halmagyi GM (2011) Transverse sinus stenting for idiopathic intracranial hypertension: a review of 52 patients and of model predictors. AJNR 32:1408–1414PubMedCrossRef Ahmed RM, Wilkinson M, Parker GD, Thurtell MJ, Macdonald J, McCluskey PJ, Allan R, Dunne V, Hanlon M, Owler BK, Halmagyi GM (2011) Transverse sinus stenting for idiopathic intracranial hypertension: a review of 52 patients and of model predictors. AJNR 32:1408–1414PubMedCrossRef
14.
go back to reference Arac A, Lee M, Steinberg GK, Marcellus M, Marks MP (2009) Efficacy of endovascular stenting in dural venous sinus stenosis for the treatment of idiopathic intracranial hypertension. Neurosurg Focus 27(5):E14PubMedCrossRef Arac A, Lee M, Steinberg GK, Marcellus M, Marks MP (2009) Efficacy of endovascular stenting in dural venous sinus stenosis for the treatment of idiopathic intracranial hypertension. Neurosurg Focus 27(5):E14PubMedCrossRef
Metadata
Title
CSF diversion in refractory idiopathic intracranial hypertension: single-centre experience and review of efficacy
Authors
Georgios Niotakis
Dionysios Grigoratos
Chris Chandler
Danny Morrison
Ming Lim
Publication date
01-02-2013
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 2/2013
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-012-1895-5

Other articles of this Issue 2/2013

Child's Nervous System 2/2013 Go to the issue