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BMC Infectious Diseases
Published in: BMC Infectious Diseases 1/2024

Open Access 06-02-2024 | Cryptococcosis | Case Report

Cryptococcosis with pulmonary cavitation in an immunocompetent child: a case report and literature review

Authors: Qiaoyan Dai, Yingshuo Wang, Qianqian Ying, Qidong Ye

Published in: BMC Infectious Diseases | Issue 1/2024

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Abstract

Background

Pulmonary cryptococcosis (PC) rarely occurs in immunocompetent children.

Case presentation

A 13-year-old boy was admitted to the First Affiliated Hospital of Ningbo University in February 2023 with complaints of cough and chest pain. Physical examination showed slightly moist rales in the right lung. Chest computed tomography (CT) suggested a lung lesion and cavitation. Blood routine test, lymphocyte subsets, immunoglobulin, and complement tests indicated that the immune system was normal. However, the serum cryptococcal antigen test was positive. Next-generation sequencing revealed Cryptococcus infection. The child was diagnosed with PC and was discharged after treating with fluconazole 400 mg. Four months later, chest CT showed that the lung lesion diminished, and reexamination of serum cryptococcal antigen test turned positive.

Conclusion

PC should be considered in an immunocompetent child with pulmonary cavities with nonspecific symptoms.
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Metadata
Title
Cryptococcosis with pulmonary cavitation in an immunocompetent child: a case report and literature review
Authors
Qiaoyan Dai
Yingshuo Wang
Qianqian Ying
Qidong Ye
Publication date
06-02-2024
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2024
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-024-09061-1

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