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BMC Sports Science, Medicine and Rehabilitation

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Open Access 01-12-2023 | Cryotherapy | Research

The influence of whole-body cryotherapy or winter swimming on the lipid profile and selected adipokines

Authors: Bartłomiej Ptaszek, Szymon Podsiadło, Artur Wójcik, Olga Czerwińska-Ledwig, Aneta Teległów

Published in: BMC Sports Science, Medicine and Rehabilitation | Issue 1/2023

Abstract

Purpose

The aim of this study was to investigate the effect of a series of 20 whole-body cryotherapy (WBC) sessions and 20 winter swimming sessions on the lipid profile and selected adipokines.

Materials/methods

The experimental group consisted of 30 people who underwent a series of WBC treatments and 30 people who underwent a winter swimming. The control group consisted of 30 people - without intervention. Study 1: on the day of the commencement of whole-body cryotherapy / at the beginning of the winter swimming season; and Study 2: after a series of 20 cryotherapy sessions / at the end of the winter swimming season. The control group was also tested twice (4-week break). There were 20 WBC treatments − 5 times a week (4 weeks) and 20 cold water baths - once a week (20 weeks).

Results

A statistically significant increase in the concentration of adiponectin, resistin and leptin in women and resistin and leptin in men was observed after the winter swimming season. Differences were also found in the second study between the groups of women using WBC and the control group, as well as the groups of women swimming and the control group. In men, however, these differences were observed in WBC and the control group. The significance level of α = 0.05 was adopted in the analyzes.

Conclusions

The use of WBC may changes in the lipid profile and selected adipokines in men. Regular winter swimming may changes of selected adipokines in both women and men.

Miller E, Kostka J, Włodarczyk T, Dugué B. Whole-body cryostimulation (cryotherapy) provides benefits for fatigue and functional status in multiple sclerosis patients. A case-control study. Acta Neurol Scand. 2016;134(6):420–6. https://doi.org/10.1111/ane.12557.CrossRefPubMed

Rivera J, Tercero MJ, Salas JS, Gimeno JH, Alejo JS. The effect of cryotherapy on fibromyalgia: a randomised clinical trial carried out in a cryosauna cabin. Rheumatol Int. 2018;38(12):2243–50. https://doi.org/10.1007/s00296-018-4176-0.CrossRefPubMedPubMedCentral

Knechtle B, Waśkiewicz Z, Sousa CV, Hill L, Nikolaidis PT. Cold Water Swimming-Benefits and risks: a narrative review. Int J Environ Res Public Health. 2020;17(23):8984. https://doi.org/10.3390/ijerph17238984.CrossRefPubMedPubMedCentral

Stanek A, Sieroń-Stołtny K, Romuk E, Cholewka A, Wielkoszyński T, Cieślar G, Kwiatek S, Sieroń A, Kawczyk-Krupka A. Whole-body Cryostimulation as an effective method of reducing oxidative stress in healthy men. Adv Clin Exp Med. 2016;25(6):1281–91. https://doi.org/10.17219/acem/65980.

Sutkowy P, Augustyńska B, Woźniak A, Rakowski A. Physical exercise combined with whole-body cryotherapy in evaluating the level of lipid peroxidation products and other oxidant stress indicators in kayakers. Oxid Med Cell Longev. 2014;2014:402631. https://doi.org/10.1155/2014/402631.CrossRefPubMedPubMedCentral

Bouzigon R, Grappe F, Ravier G, Dugue B. Whole- and partial-body cryostimulation/cryotherapy: current technologies and practical applications. J Therm Biol. 2016;61:67–81. https://doi.org/10.1016/j.jtherbio.2016.08.009.CrossRefPubMed

Hirvonen H, Kautiainen H, Moilanen E, Mikkelsson M, Leirisalo-Repo M. The effect of cryotherapy on total antioxidative capacity in patients with active seropositive rheumatoid arthritis. Rheumatol Int. 2017;37(9):1481–7. https://doi.org/10.1007/s00296-017-3771-9.CrossRefPubMed

Stanek A, Wielkoszyński T, Bartuś S, Cholewka A. Whole-body Cryostimulation improves inflammatory endothelium parameters and decreases oxidative stress in healthy subjects. Antioxidants. 2020;9(12):1308. https://doi.org/10.3390/antiox9121308.CrossRefPubMedPubMedCentral

Lubkowska A, Bryczkowska I, Szygula Z, Giemza C, Skrzek A, Rotter I, Lombardi G, Banfi G. The effect of repeated whole-body cryostimulation on the HSP-70 and lipid metabolisms in healthy subjects. Physiol Res. 2019;68(3):419–29. https://doi.org/10.33549/physiolres.933954.CrossRefPubMed

10.

Lubkowska A, Dołęgowska B, Szyguła Z. Whole-body cryostimulation–potential beneficial treatment for improving antioxidant capacity in healthy men–significance of the number of sessions. PLoS ONE. 2012;7(10):e46352. https://doi.org/10.1371/journal.pone.0046352.CrossRefPubMedPubMedCentral

11.

Lubkowska A, Dołęgowska B, Szyguła Z, Bryczkowska I, Stańczyk-Dunaj M, Sałata D, Budkowska M. Winter-swimming as a building-up body resistance factor inducing adaptive changes in the oxidant/antioxidant status. Scand J Clin Lab Invest. 2013;73(4):315–25. https://doi.org/10.3109/00365513.2013.773594.CrossRefPubMed

12.

Kolettis TM, Kolettis MT. Winter swimming: healthy or hazardous? Evidence and hypotheses. Med Hypotheses. 2003 Nov-Dec;61(5–6):654–6. https://doi.org/10.1016/s0306-9877(03)00270-6.

13.

Miller E, Markiewicz Ł, Saluk J, Majsterek I. Effect of short-term cryostimulation on antioxidative status and its clinical applications in humans. Eur J Appl Physiol. 2012;112(5):1645–52. https://doi.org/10.1007/s00421-011-2122-x.CrossRefPubMed

14.

Teległów A, Romanovski V, Skowron B, Mucha D, Tota Ł, Rosińczuk J, Mucha D. The Effect of Extreme Cold on Complete blood count and biochemical indicators: a Case Study. Int J Environ Res Public Health. 2021;19(1):424. https://doi.org/10.3390/ijerph19010424.CrossRefPubMedPubMedCentral

15.

Teległów A, Dąbrowski Z, Marchewka A, Tyka A, Krawczyk M, Głodzik J, Szyguła Z, Mleczko E, Bilski J, Tyka A, Tabarowski Z, Czepiel J, Filar-Mierzwa K. The influence of winter swimming on the rheological properties of blood. Clin Hemorheol Microcirc. 2014;57(2):119–27. https://doi.org/10.3233/CH-141823.CrossRefPubMed

16.

Rymaszewska J, Lion KM, Pawlik-Sobecka L, Pawłowski T, Szcześniak D, Trypka E, Rymaszewska JE, Zabłocka A, Stanczykiewicz B. Efficacy of the whole-body cryotherapy as add-on therapy to Pharmacological Treatment of Depression-A Randomized Controlled Trial. Front Psychiatry. 2020;11:522. https://doi.org/10.3389/fpsyt.2020.00522.CrossRefPubMedPubMedCentral

17.

Huttunen P, Kokko L, Ylijukuri V. Winter swimming improves general well-being. Int J Circumpolar Health. 2004;63(2):140–4. https://doi.org/10.3402/ijch.v63i2.17700.CrossRefPubMed

18.

van Tulleken C, Tipton M, Massey H, Harper CM. Open water swimming as a treatment for major depressive disorder. BMJ Case Reports. 2018;bcr–2018–225007. https://doi.org/10.1136/bcr-2018-225007.

19.

Checinska-Maciejewska Z, Miller-Kasprzak E, Checinska A, Korek E, Gibas-Dorna M, Adamczak-Ratajczak A, Bogdanski P, Krauss H. Gender-related effect of cold water swimming on the seasonal changes in lipid profile, ApoB/ApoA-I ratio, and homocysteine concentration in cold water swimmers. J Physiol Pharmacol. 2017;68(6):887–96.PubMed

20.

Wang F, Li S. Research on the influence mechanism of winter swimming exercise on the cardiovascular system in the middle-aged and elderly. Matrix Sci Pharma. 2019;3:12–5. https://doi.org/10.4103/MTSP.MTSP_4_19.CrossRef

21.

Kokocińska A, Adamczyk P, Ponikowska I. What does winter swimming have to do with balneotherapy? 2021, https://doi.org/10.36740/ABal202101109.

22.

Hausswirth C, Schaal K, Le Meur Y, Bieuzen F, Filliard JR, Volondat M, Louis J. Parasympathetic activity and blood catecholamine responses following a single partial-body cryostimulation and a whole-body cryostimulation. PLoS ONE. 2013;8(8):e72658. https://doi.org/10.1371/journal.pone.0072658.CrossRefPubMedPubMedCentral

23.

Kepinska M, Gdula-Argasinska J, Dabrowski Z, Szarek M, Pilch W, Kreska-Korus A, Szygula Z. Fatty acids composition in erythrocyte membranes of athletes after one and after a series of whole body cryostimulation sessions. Cryobiology. 2017;74:121–5. https://doi.org/10.1016/j.cryobiol.2016.11.005.CrossRefPubMed

24.

Lubkowska A, Szygula Z, Klimek AJ, Torii M. Do sessions of cryostimulation have influence on white blood cell count, level of IL6 and total oxidative and antioxidative status in healthy men? Eur J Appl Physiol. 2010;109(1):67–72. https://doi.org/10.1007/s00421-009-1207-2.CrossRefPubMed

25.

Rymaszewska J, Urbanska KM, Szczesniak D, Stanczykiewicz B, Trypka E, Zablocka A. The improvement of memory deficits after whole-body cryotherapy - the First Report. Cryo Lett. 2018 May/Jun;39(3):190–5.

26.

Lombardi G, Ziemann E, Banfi G. Whole-body cryotherapy in athletes: from therapy to Stimulation. An updated review of the literature. Front Physiol. 2017;8:258. https://doi.org/10.3389/fphys.2017.00258.CrossRefPubMedPubMedCentral

27.

Feingold KR. Introduction to Lipids and Lipoproteins. [Updated 2021 Jan 19]. In: Feingold KR, Anawalt B, Boyce A, editors. Endotext. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK305896/.

28.

Pilch W, Piotrowska A, Wyrostek J, Czerwińska-Ledwig O, Ziemann E, Antosiewicz J, Zasada M, Kulesa-Mrowiecka M, Żychowska M. Different changes in Adipokines, lipid Profile, and TNF-Alpha levels between 10 and 20 whole body Cryostimulation Sessions in individuals with I and II degrees of obesity. Biomedicines. 2022;10(2):269. https://doi.org/10.3390/biomedicines10020269.CrossRefPubMedPubMedCentral

29.

Rymaszewska JE, Stańczykiewicz B, Lion K, Misiak B. The impact of whole-body cryotherapy on lipid profile: a systematic review and meta-analysis. Complement Ther Med. 2020;55:102568. https://doi.org/10.1016/j.ctim.2020.102568.CrossRefPubMed

30.

Mazur A, Matusik P, Małecka-Tendera E. Tkanka tłuszczowa jako narząd wydzielania wewnętrznego. Pediatr Pol. 2010;85:255–64.CrossRef

31.

Wiecek M, Szymura J, Sproull J, Szygula Z. Decreased blood asprosin in hyperglycemic menopausal women as a result of whole-body cryotherapy regardless of metabolic syndrome. J Clin Med. 2019;8(9):1428. https://doi.org/10.3390/jcm8091428.CrossRefPubMedPubMedCentral

32.

Stanek A, Cholewka A, Wielkoszyński T, Romuk E, Sieroń A. Whole-body cryotherapy decreases the levels of inflammatory, oxidative stress, and atherosclerosis plaque markers in male patients with active-phase ankylosing spondylitis in the absence of Classical Cardiovascular Risk factors. Mediators Inflamm. 2018;2018:8592532. https://doi.org/10.1155/2018/8592532.CrossRefPubMedPubMedCentral

33.

Siemińska L. Adipose tissue. Pathophysiology, distribution, sex differences and the role in inflammation and cancerogenesis. Endokrynol Pol. 2007;58:330–42.PubMed

34.

Makki K, Froguel P, Wolowczuk I. Adipose tissue in obesity-related inflammation and insulin resistance: cells, cytokines, and Chemokines. ISRN Inflamm. 2013;2013:139239.CrossRefPubMedPubMedCentral

35.

Ptaszek B, Teległów A, Adamiak J, Głodzik J, Podsiadło S, Mucha D, Marchewka J, Halski T, Mucha D. Effect of whole-body cryotherapy on morphological, rheological and biochemical indices of blood in people with multiple sclerosis. J Clin Med. 2021;10(13):2833. https://doi.org/10.3390/jcm10132833.CrossRefPubMedPubMedCentral

36.

Lubkowska A, Banfi G, Dołegowska B, d’Eril GV, Łuczak J, Barassi A. Changes in lipid profile in response to three different protocols of whole-body cryostimulation treatments. Cryobiology. 2010;61(1):22–6. https://doi.org/10.1016/j.cryobiol.2010.03.010.CrossRefPubMed

37.

Stanek A, Romuk E, Wielkoszyński T, Bartuś S, Cieślar G, Cholewka A. Decreased lipid Profile and oxidative stress in healthy subjects who underwent whole-body cryotherapy in closed cryochamber with subsequent kinesiotherapy. Oxid Med Cell Longev. 2019;2019:7524878. https://doi.org/10.1155/2019/7524878.CrossRefPubMedPubMedCentral

38.

Ziemann E, Olek RA, Grzywacz T, Kaczor JJ, Antosiewicz J, Skrobot W, Kujach S, Laskowski R. Whole-body cryostimulation as an effective way of reducing exercise-induced inflammation and blood cholesterol in young men. Eur Cytokine Netw. 2014;25(1):14–23. https://doi.org/10.1684/ecn.2014.0349.CrossRefPubMed

39.

Lubkowska A, Dudzińska W, Bryczkowska I, Dołęgowska B, Body Composition L, Profile. Adipokine Concentration, and antioxidant capacity changes during interventions to treat overweight with Exercise Programme and whole-body Cryostimulation. Oxid Med Cell Longev. 2015;2015:803197. https://doi.org/10.1155/2015/803197.CrossRefPubMedPubMedCentral

40.

Kozłowska-Flis M, Rodziewicz-Flis E, Micielska K, Kortas J, Jaworska J, Borkowska A, Sansoni V, Perego S, Lombardi G, Ziemann E. Short and long-term effects of high-intensity interval training applied alone or with whole-body cryostimulation on glucose homeostasis and myokine levels in overweight to obese subjects. Front Biosci (Landmark Ed). 2021;26(11):1132–46. https://doi.org/10.52586/5015.CrossRefPubMed

41.

Gordon DJ, Bm R. High-density lipoprotein—the clinical implications of recent studies. N Engl J Med. 1989;321(19):1311–6.CrossRefPubMed

42.

Bryczkowska I, Radecka A, Knyszyńska A, Łuczak J, Lubkowska A. Effect of whole body cryotherapy treatments on antioxidant enzyme activity and biochemical parameters in patients with multiple sclerosis. Fam Med Prim Care Rev. 2018;20:214–7. https://doi.org/10.5114/fmpcr.2018.78253.CrossRef

43.

Misiorek A, Kulis A, Głodzik J, Wrześniewski K, Marchewka A. The effect of whole-body cryotherapy on the lipid profile and blood glucose concentration in older women. Acta Bio-Optica et Inform Med. 2018;24:90–8.

44.

Vallerand AL, Jacobs I. Rates of energy substrates utilization during human cold exposure. Eur J Appl Physiol Occup Physiol. 1989;58(8):873–8.CrossRefPubMed

45.

Yizhen N, Zhaoqi Y, Wei Y, Xia Q. YZ. Cold exposure stimulates lipid metabolism, induces inflammatory response in the adipose tissue of mice and promotes the osteogenic differentiation of BMMSCs via the p38 MAPK pathway in vitro. Int J Clin Pathol. 2015.

46.

Banfi G, Melegati G, Barassi A et al. Effects of whole-body cryotherapy on serum mediators of inflammation and serum muscle enzymes in athletes. J Therm Biol. 2009.

47.

Stanek A, Cieslar G, Strzelczyk J, et al. Influence of cryogenic temperatures on inflammatory markers in patients with ankylosing spondylitis. Pol J Environ Stud. 2010;19(1):167–75.

48.

Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature. 1994;372(6505):425–32. https://doi.org/10.1038/372425a0.CrossRefPubMed

49.

Meier U, Gressner AM. Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin. Clin Chem. 2004;50(9):1511–25. https://doi.org/10.1373/clinchem.2004.032482.CrossRefPubMed

50.

Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med. 1996;334(5):292–5. https://doi.org/10.1056/NEJM199602013340503.CrossRefPubMed

51.

Lushchyk M, Danilova L, Tuzava H, et al. Whole body cryotherapy effect on weight gain and metabolic parameters in metabolic and type 2 diabetic patients. Endocr Abstracts. 2019;63:P930. https://doi.org/10.1530/endoabs.63.P930.CrossRef

52.

Gibas-Dorna M, Checinska Z, Korek E, Kupsz J, Sowinska A, Wojciechowska M, Krauss H, Piątek J. Variations in leptin and insulin levels within one swimming season in non-obese female cold water swimmers. Scand J Clin Lab Invest. 2016;76(6):486–91. https://doi.org/10.1080/00365513.2016.1201851.CrossRefPubMed

53.

Fedewa MV, Hathaway ED, Ward-Ritacco CL, Williams TD, Dobbs WC. The Effect of Chronic Exercise Training on Leptin: a systematic review and Meta-analysis of Randomized controlled trials. Sports Med. 2018;48(6):1437–50. https://doi.org/10.1007/s40279-018-0897-1. PMID: 29582381.CrossRefPubMed

54.

Izquierdo AG, Crujeiras AB, Casanueva FF, Carreira MC, Leptin. Obesity, and Leptin Resistance: Where Are We 25 Years Later? Nutrients 2019, 11, 2704.

55.

Hernandez V, Kaur K, ElSharief MW, Al Hajaj SW, Ebrahim AM, Razack M, Dragas D. The New Kid on the Block: the Mechanisms of Action of Hyperleptinemia in Coronary Artery Disease and Atherosclerosis. Volume 13. Cureus; 2021. p. e15766.

56.

Ahima RS, Lazar MA. Adipokines and the peripheral and neural control of Energy Balance. Mol Endocrinol. 2008;22:1023–31.CrossRefPubMedPubMedCentral

57.

Maia-Fernandes T, Roncon-Albuquerque R Jr, Leite-Moreira AF. Cardiovascular actions of adiponectin: pathophysiologic implications. Rev Port Cardiol. 2008;27(11):1431–49.PubMed

58.

Pischon T, Rimm EB. Adiponectin and risk of acute coronary syndromes: defining the obesity phenotype. Eur Heart J. 2007;28(3):274–5. https://doi.org/10.1093/eurheartj/ehl454.CrossRefPubMed

59.

Simpson KA, Singh MA. Effects of exercise on adiponectin: a systematic review. Obes (Silver Spring). 2008;16(2):241–56. https://doi.org/10.1038/oby.2007.53. PMID: 18239630.CrossRef

60.

Furukawa S, Fujita T, Shimabukuro M, Iwaki M, Yamada Y, Nakajima Y, Nakayama O, Makishima M, Matsuda M, Shimomura I. Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Investig. 2004;114:1752–61.CrossRefPubMedPubMedCentral

61.

Ziemann E, Olek RA, Grzywacz T, Antosiewicz J, Kujach S, Łuszczyk M, Smaruj M, Sledziewska E, Laskowski R. Whole-body cryostimulation as an effective method of reducing low-grade inflammation in obese men. J Physiol Sci. 2013;63(5):333–43. https://doi.org/10.1007/s12576-013-0269-4.CrossRefPubMedPubMedCentral

62.

Chen BH, Song Y, Ding EL, Roberts CK, Manson JE, Rifai N, Buring JE, Gaziano JM, Liu S. Circulating levels of resistin and risk of type 2 diabetes in men and women: results from two prospective cohorts. Diabetes Care. 2009;32(2):329–34. https://doi.org/10.2337/dc08-1625.CrossRefPubMedPubMedCentral

63.

Cobbold C. Type 2 diabetes mellitus risk and exercise: is resistin involved? J Sports Med Phys Fitness. 2019;59(2):290–297. https://doi.org/10.23736/S0022-4707.18.08258-0. Epub 2018 Mar 1. PMID: 29498254.

64.

Kyrou I, Randeva HS, Tsigos C et al. Clinical Problems Caused by Obesity. [Updated 2018 Jan 11]. In: Feingold KR, Anawalt B, Boyce A., editors. Endotext. South Dartmouth (MA): MDText.com, Inc.; 2000. Available from: https://www.ncbi.nlm.nih.gov/books/NBK278973/.

Title: The influence of whole-body cryotherapy or winter swimming on the lipid profile and selected adipokines
Authors: Bartłomiej Ptaszek
Szymon Podsiadło
Artur Wójcik
Olga Czerwińska-Ledwig
Aneta Teległów
Publication date: 01-12-2023
Publisher: BioMed Central
Keywords: Cryotherapy
Cryotherapy
Published in: BMC Sports Science, Medicine and Rehabilitation / Issue 1/2023
Electronic ISSN: 2052-1847
DOI: https://doi.org/10.1186/s13102-023-00744-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The influence of whole-body cryotherapy or winter swimming on the lipid profile and selected adipokines

Abstract

Purpose

Materials/methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Materials/methods

Results

Conclusions

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