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International Journal of Colorectal Disease

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01-12-2020 | Crohn's Disease | Short Communication

Ileostomy reversal after subtotal colectomy in Crohn’s disease: a single institutional experience at a high-volume center

Authors: Daniel Bitner, Anthony D’Andrea, Robert Grant, Prerna Khetan, Alexander J. Greenstein

Published in: International Journal of Colorectal Disease | Issue 12/2020

Abstract

Purpose

Our aim was to evaluate factors leading to ostomy reversal among a group of 44 patients with Crohn’s disease (CD) who underwent subtotal colectomy (STC) between June 2011 and September 2018.

Methods

Our study design was a retrospective chart review. Patients with CD who underwent STC were included. Logistic regression analysis was used to evaluate several risk factors for non-reversal including medications received prior to surgery and indication for STC.

Results

Of 44 STCs performed, 31 (70.5%) were completed laparoscopically and 13 required an open approach (29.5%). Nine patients (20.4%) underwent ostomy reversal, and the mean time to reversal was 8.4 months. Preoperative therapy with an immunomodulator or biologic was associated with ostomy reversal (OR and CI: 0.43, 0.09–0.93; 0.47, 0.10–0.96), as was a diagnosis of intraabdominal abscess (0.43, 0.09–0.93).

Conclusion

Ileostomy reversal after STC in Crohn’s disease is uncommon. Certain treatment regimens and diagnostic factors may impact the likelihood of ostomy reversal. Based on the available data, patients with CD whose disease is severe enough to require STC should be counseled that their ostomy will most likely be permanent. However, due to the low incidence of this procedure for CD, more data is needed.

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Title: Ileostomy reversal after subtotal colectomy in Crohn’s disease: a single institutional experience at a high-volume center
Authors: Daniel Bitner
Anthony D’Andrea
Robert Grant
Prerna Khetan
Alexander J. Greenstein
Publication date: 01-12-2020
Publisher: Springer Berlin Heidelberg
Keywords: Crohn's Disease
Chronic Inflammatory Bowel Disease
Immunomodulator
Subtotal Colectomy
Ileostomy
Subtotal Colectomy
Published in: International Journal of Colorectal Disease / Issue 12/2020
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI: https://doi.org/10.1007/s00384-020-03709-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Ileostomy reversal after subtotal colectomy in Crohn’s disease: a single institutional experience at a high-volume center

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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