Critical Care

Protective role of autophagy in mouse cecal ligation and puncture-induced sepsis model

W Takahashi, H Hatano, H Hirasawa, S Oda

Reversible depressive effect of TNFα on a model of isolated perfused rat heart

BV Nguyen, M Guillouet, MA Giroux-Metges, G Gueret, M Ould-Ahmed, JP Pennec

Effect of cdp-choline on microcirculatory alterations during endotoxemia

K Schmidt, M Doerr, T Brenner, S Hofer, A Walther

Immune response after stimulation with wall components of Gram-positive bacteria

S Aloizos, E Tsigou, P Myrianthefs, S Gourgiotis, A Tsakris, G Baltopoulos

Correlation of the oxygen radical activity and antioxidants and severity in critically ill surgical patients: preliminary report

J Lee, H Shim, JY Jang

Simultaneous analysis of the expression of CD64 and HLA-DR in the peripheral blood and bronchoalveolar lavage fluid in sepsis

T Skirecki, M Mikaszewska-Sokolewicz, G Hoser, U Zielińska-Borkowska

Anti-inflammatory effects of Kupffer cells through α7-nicotinic acetylcholine receptors

Y Li, X Shi

Prevention of sepsis by correcting apoptosis

M Puhtinskaya, V Estrin

Immune paralysis in trauma patients; implications for prehospital intervention

M Kox, K Timmermans, M Vaneker, GJ Scheffer, P Pickkers

Is hemoglobin concentration affected by sepsis in the acute phase?

G Jansma, H Buter, RT Gerritsen, EC Boerma

Do changes in red blood cell deformability in patients with septic shock correlate with changes in SOFA scores?

T Clark, S Jewell, M Sair, P Petrov, P Winlove

Do erythrocytes subjected to cardiopulmonary bypass exhibit changes in their membrane mechanical properties?

T Clark, S Jewell, M Sair, P Petrov, P Winlove

Platelet-associated oxidative stress and ADAMTS-13 levels are inversely associated with a poor prognosis in septic shock

L Montini, G De Pascale, MA Pennisi, ES Tanzarella, SL Cutuli, A Occhionero, R De Cristofaro, M Antonelli

Neutrophil gelatinase-associated lipocalin/lipocalin2, derived from gut crypt cells, exerts intestinal antimicrobial effect via bacterial stimulation of Toll-like receptor 4 and 9

K Mori, T Igarashi, K Inoue, T Suzuki, H Morisaki, J Takeda

Lethal influenza virus A H1N1 infection in two relatives with autosomal dominant GATA-2 deficiency

J Sole-Violan, I Sologuren, E Betancor, S Zhang, C Pérez, E Herrera-Ramos, M Martínez-Saavedra, M López-Rodríguez, J Pestano, J Ruiz-Hernández, J Ferrer, F Rodríguez de Castro, J Casanova, C Rodríguez-Gallego

Bacterial translocation primes proinflammatory responses and is connected to early death in an experimental model of lethal injury

N Baxevanos, T Tsaganos, A Pistiki, D Droggiti, A Spyridaki, E Giamarellos-Bourboulis

Effects of the common 34C>T variant of the AMPD1 gene on immune function, multiorgan dysfunction and mortality in patients with sepsis

B Ramakers, E Giamarellos-Bourboulis, M Coenen, M Kox, J Van der Hoeven, C Routsi, A Savva, I Perdios, F Diamantea, D Sinapidis, P Smits, N Riksen, P Pickkers

Exploring the translational disconnect between the murine and human inflammatory response: in vitro analysis of the dose-response relationship of LPS and NFκB activation in murine and human immune cells

EP McCarron, I Welters, D Williams, D Antoine, A Kipar

Hypogammaglobulinemia in sepsis is not correlated to high circulating angiopoietin-2 levels

U Kovačič, F Starič, M Kmet, M Godnič, R Kapš

TREM-1 levels are elevated in patients with liver cirrhosis

SD Gurney, CR Graham, P Kelleher, N Soni, M Foxton, S Singh

Effects of different doses and serotypes of LPS on blood-brain barrier permeability in Sprague-Dawley rats

E Senturk, F Esen, P Ergin Ozcan, G Orhun, N Orhan, N Arican, M Kucuk, M Kaya

Bioenergetic imbalance and oxidative stress in the pathophysiology of septic encephalopathy

J D'Avila, R Rodrigues, H Castro-Faria-Neto, M Oliveira, F Bozza

Pathophysiology of sepsis-associated brain dysfunction: an experimental study of cerebral microdialysis and mitochondrial function

P Kurtz, C Vargas-Lopes, C Madeira, I Mello, R Panizzutti, L C Azevedo, F A Bozza

Cholinergic modulation of hippocampal activity during septic encephalopathy

A Zivkovic, CP Bengtson, O Sedlaczek, R Von Haken, H Bading, S Hofer

Neutrophil-lymphocyte count ratio as a biomarker of severe sepsis in Escherichia coli infections in adults

LR Ljungstrom, G Jacobsson, R Andersson

Obesity and inflammatory markers in severe sepsis

P Simon, D Thomas-Rüddel, T Nemes, K Reinhart, F Bloos, UX Kaisers

Cytokine gene expression can predict infectious complications following severe trauma

HD Torrance, K Brohi, CJ Hinds, MJ O'Dwyer

A cohort study of routinely used sepsis biomarkers and 28-day mortality

M De La Torre-Prados, A Garcia-De la Torre, C Trujillano-Férnández

Procalcitonin as prognostic marker of mortality

S Zampieri, P Bettonte, M Ortolani, G Frison, V Schweiger, L Gottin, E Polati

Changes in circulating procalcitonin versus C-reactive protein in predicting evolution of infectious disease in febrile, critically ill patients

S Hoeboer, J Groeneveld

Procalcitonin-guided antibiotic therapy in patients with congestive heart failure and suspicion of lower respiratory tract infection: results from a randomized trial

P Schuetz, E Grolimund, A Kutz, S Haubitz, B Mueller

Pro-adrenomedullin as a clinical predictor after cardiac surgery

J Van Fessem, F De Graaf, J Van Paassen, S Arbous

Pro-adrenomedullin as prognostic biomarker in the sepsis

M De La Torre-Prados, A Garcia-De la Torre, A Enguix, M Mayor, N Zamboschi, C Trujillano-Fernández, A Garcia-Alcantara

Early IL-6 response in sepsis is correlated with mortality and severity score

P Srisangthong, A Wongsa, P Kittiworawitkul, A Wattanathum

Compared values of presepsin (sCD14-ST) and procalcitonin as early markers of outcome in severe sepsis and septic shock: a preliminary report from the Albumin Italian Outcome Sepsis (ALBIOS) study

P Caironi, S Masson, E Spanuth, R Thomae, R Fumagalli, A Pesenti, M Romero, G Tognoni, R Latini, L Gattinoni

Usefulness of presepsin in the diagnosis of sepsis in acute kidney injury patients

Y Nakamura, H Ishikura, T Nishida, Y Kawanno, R Yuge, R Ichiki, A Murai

Serum levels of presepsin reffects the APACHE II and SOFA scores in patients with sepsis

R Sato, Y Suzuki, M Sato, G Takahashi, M Kojika, Y Inoue, S Endo

Relationship between serum nitrite/nitrate levels in the early phase of septic acute lung injury and prognosis

M Sato, Y Suzuki, T Masuda, G Takahashi, M Kojika, Y Inoue, S Endo

Simple and fast prediction of Legionella sp. in community-acquired pneumonia: validation of a prediction rule

S Haubitz, F Hitz, L Graedel, T Wiemken, P Peyrani Dicastelnuovo, J Ramirez, M Batschwaroff, C Fux, B Mueller, P Schütz

Host genetic variants associated with community-acquired pneumonia

LE Salnikova, TV Smelaya, VV Moroz, A Golubev, AV Rubanovich

Outcome of severe community-acquired pneumonia: the impact of comorbidities

JM Pereira, JA Paiva, F Froes, JP Baptista, J Gonçalves-Pereira

Outcomes in urinary sepsis

C Joya-Montosa, E Trujillo-Garcia, MJ Delgado-Amaya, E Curiel-Balsera

Nosocomial pneumonia in the postoperative period after heart transplantation

R Gómez López, P Fernández Ugidos, P Vidal Cortes, M Bouza Vieiro, J Miñiz, S Fojon Polanco, M Paniagua Martin, R Marzoa Rivas, E Barge Caballero, M Crespo Leiro

Abdominal infection plays a role in the incidence of ventilator-associated pneumonia

GB Bouroche, S Ruckly, B Misset, JF Timsit, F Philippart

Incidence and risk factors for ventilator-associated pneumonia in Siriraj Hospital

O Chaiwat, S Nakaviroj

Hospital-acquired bloodstream infection: Indian perspective

R Agrawal, A Varma

Risk factors for catheter-related bloodstream infections in a surgical ICU

A Kundakci, O Ozkalayci, P Zeyneloglu, H Arslan, A Pirat

Analysis of risk factors for catheter-related bloodstream infection in a parenteral nutrition population

I Conrick-Martin, M McGovern, K Boner, J Bourke, E Fitzgerald, R Hone, M Lynch, D Phelan, C Walshe

Can we predict the postoperative infections?

T Mózes, K Gornicsar, A Grosz, ZS Domján, I Buzogány

Results for introduction of a new hand hygiene program in the ICU

P Vos, A Harts-Laurijsen, R Snoeren, R Ramnarain, JA Van Oers

Improving hand hygiene performance in a surgical ICU: a novel method for data collection to change physician behavior

SA Nasraway

Compliance with the implementation of an ICU cluster-randomized trial assessing the benefits and potential harms of universal glove and gowning

D Kett, DJ Morgan, L Pineles, MJ Zervos, LS Munoz-Price, AD Harris, BUGG Investigators

Fighting hospital sepsis

AR Calini, S Vesconi, R Fumagalli, S Marchesi, L Ghezzi, G Monti

Sinks as a correctable source of ESBL contamination for patients in the ICU

I Wolf, P Bergervoet, W Van der Zwet, H Van den Oever, P Savelkoul, F Sebens

Hemodynamic and mitochondrial effects of enalapril in experimental sepsis

AJ Pereira, V Jeger, T Corrêa, M Vuda, S Djafarzadeh, J Takala, S Jakob

Effects of intraperitoneal immunoglobulin therapy on behavior and cognitive functions in CLP-induced sepsis model in rats

F Esen, E Senturk, P Ergin Ozcan, G Orhun, S Gümrü, M Kaya, N Orhan, N Arican, F Aricioglu

Clinical efficacy of recombinant human soluble thrombomodulin in patients with septic disseminated intravascular coagulation

Y Suzuki, R Sato, M Sato, S Endo

Antithrombin III concentrate therapy may have an efficacy in sepsis

N Saito, M Takeda, T Harada, R Moroi, M Namiki, A Yaguchi

A clinical randomized trial on the use of atorvastatin in patients with sepsis or septic shock: effects on endothelial function

K Prado, C Ribeiro, T Furian, R Pinto Ribeiro, D Silvello, L Rohde, N Clausell, L Becker

A multicenter randomized controlled study of an extracorporeal cytokine hemoadsorption device in septic patients

D Schädler, C Porzelius, A Jörres, G Marx, A Meier-Hellmann, C Putensen, M Quintel, C Spies, C Engel, N Weiler, M Kuhlmann

Continuous renal replacement therapy with the adsorbent membrane oXiris in septic patients: a clinical experience

F Turani, F Candidi, R Barchetta, E Grilli, A Belli, E Papi, A di Marzio, M Falco

Combined use of pumpless extracorporeal lung assist system and continuous renal replacement therapy with citrate anticoagulation in polytrauma patients

HK Atalan, M Dumantepe, TB Denizalti, IA Tarhan, A Ozler

Abstract withdrawn

Use of extracorporeal endotoxin elimination therapy for septic shock

BA Adamik, JS Smiechowicz, SZ Zielinski, AK Kübler

Selective adsorption of lipopolysaccharide in the complex treatment of patients with severe sepsis

S Rei, I Aleksandrova, V Kiselev, M Ilynskiy, G Berdnikov, L Marchenkova, G Bulava, N Borovkova

Alteco endotoxin hemoadsorption in Gram-negative septic shock patients

HP Shum, KC Chan, WW Yan

Steroid therapy in septic shock: survey of practice amongst UK critical care physicians

G Rajendran, K Dasari, A Dhrampal

Need for restoration of cortisol serum levels for successful antimicrobial therapy in experimental sepsis

T Doulias, A Pistiki, P Christopoulos, V Papaziogas, E Giamarellos-Bourboulis, I Koutelidakis

Impact of time to initiation of appropriate antibiotic therapy on early mortality of patients with septic shock

JP Quenot, C Binquet, S Vinault, A Pavon

Comparison of survivors and nonsurvivors in 27 confirmed injectional anthrax cases from the 2009 outbreak in Scotland

M Booth, L Donaldson, C Xizhong, S Junfeng, P Eichacker

Efficacy and utility of preemptive anti-Gr(+) coverage in selected critically ill patients

VT Todorova, SM Milanov, G Georgiev, M Milanov

Gram-negative resistance and need for ICU among urinary tract infections in the United States

M Zilberberg, A Shorr

Multidrug resistance among P. aeruginosa and Enterobacteriaceae in US hospitals, 2000 to 2009

M Zilberberg, A Shorr

Prevalence of multidrug resistance, extensive drug resistance and pandrug resistance among multiple Gram-negative isolates: experience in a tertiary-care hospital ICU in North India

S Dewan, T Sahoo, N Chandra, A Varma

Risk factors associated with Acinetobacter baumannii septicemia and its mortality rates in critically ill patients

K Kontopoulou, K Tsepanis, I Sgouropoulos, A Triantafyllidou, D Socratous, P Tassioudis, E Chasou, E Antypa, F Renta, E Antoniadou, K Mandraveli

Prevalence of colonization by multiresistant bacteria on admission to the ICU in the French military hospital in Kabul, Afghanistan

JV Schaal, P Pasquier, H Delacour, A Salvadori, A Jarrassier, JR Renner, SM Mérat

Extended-spectrum ß-lactamase Providencia stuartii in a general ICU

P Myrianthefs, E Evodia, G Fildissis, G Baltopoulos

High-dose tigecycline use in severe infections

G De Pascale, L Montini, T Spanu, V Bernini, A Occhionero, DL Grieco, M Biancone, P De Santis, ES Tanzarella, SL Cutuli, MA Pennisi, MA Antonelli

In vitro efficiency of Amikacin Inhale, a novel drug-device delivery system

N Kadrichu, S Boc, K Corkery, P Challoner

Analysis of parameters in critically ill patients influencing amikacin peak levels

IM Hollevoet, SJ Toye, J De Waele

Cost implication of antibiotic-associated diarrhoea and the financial impact of probiotic use in its prevention

C Ebm, M Cecconi, C Moran, A Rhodes, T Rahman

Empirical versus preemptive antimycotic therapy in terms of outcome benefit

S Milanov, VT Todorova, G Georgiev, M Milanov

Impact of echinocandins as first-choice therapy in cardiothoracic high-risk patients with candidemia

G Langebartels, Y Choi, J Catteleans, T Wahlers

Fungal ventricular assist device infections occur in colonized patients and are associated with high mortality rate

P Gaudard, J Eliet, N Zeroual, G Culas, P Colson

Cost-effectiveness analysis of anidulafungin in the treatment of candidaemia

G Auzinger, G Playford, C Graham, H Narula, C Charbonneau, D Weinstein, M Kantecki, H Schlamm, M Ruhnke

Prevalence and impact of invasive fungal infections in intensive care

JM Patel, K Couper, T Melody, R O'Brien, D Parekh

Beliefs and actual practice of oxygen therapy in the ICU

HJ Helmerhorst, MJ Schultz, PH Van der Voort, E De Jonge, DJ Van Westerloo

FiO2/PEEP index: a simple tool for opitimizing ventilator settings

D Trasy, M Nemeth, K Kiss, Z Till, Z Molnar

Use of high-flow nasal canulae: effect on alveolar pressure and its limitation

H Hayami, K Mizutani, M Shioda, S Takaki, H Maejima, K Ueno, Y Yamaguchi, T Kariya, T Gotoh

Relation between PaO2/FiO2 ratio, SpO2/FiO2 ratio, oxygenation index and ventilation ratio in critically ill patients

T Aslanidis, A Myrou, E Chytas, E Anastasiou, E Geka, E Efthimiou, V Ourailoglou, I Soultati, S Primikiri, M Giannakou-Peftoulidou

Decreased respiratory complexity during apnea in acute respiratory distress syndrome

A Batchinsky, C Necsoiu, T Langer, V Vecchi, W Baker, J Salinas, L Cancio

Acute respiratory distress syndrome - the Berlin definition: impact on an ICU of a university hospital

A Agrifoglio, J Lopez, J Figueira, M Hernández, L Fernández, M Irazabal, S Yus, M Jiménez

Extravascular lung water, B-type natriuretic peptide and blood volume contraction for diagnosing weaning-induced pulmonary edema

M Dres, JL Teboul, N Anguel, C Richard, X Monnet

Pressure support ventilation with minimal sedation as the main ventilatory mode in critically ill patients with lung injury: effect on mortality and incidence of complications

A Gomez, A Leon, G Fernandez, G Montenegro, H Gomez

Comparison of a fully automatic ARDSNet protocol and a feedback-controlled open lung management concept

A Pomprapa, D Schwaiberger, B Lachmann, S Leonhardt

Comparison of an entirely automated ventilation mode, Intellivent-ASV, with conventional ventilation in ARDS patients: a 48-hour study

E Bialais, L Vignaux, X Wittebole, D Novotni, J Meyer, M Wysocki, T Sottiaux, G Reychler, J Roeseler, P Laterre, P Hantson

Difference in pulmonary permeability between indirect and direct acute respiratory distress syndrome assessed by the transpulmonary thermodilution technique

K Morisawa, Y Taira, M Yanai, Y Takamatu, S Kushimoto, S Fujitani

Biomarkers for early stage of acute respiratory distress syndrome in septic patients: surfactant protein D and Clara cell protein

A Kuzovlev, V Moroz, A Goloubev, S Polovnikov

Intravenous perfluorocarbons for prevention of ventilator-associated ARDS

A Scultetus, A Haque, F Arnaud, G McNamee, C Auker, R McCarron, P McKay, R Mahon

Effect of angiotensin-converting enzyme gene I/D polymorphism and its expression on clinical outcome in acute respiratory distress syndrome

I Tsangaris, A Tsantes, P Kopterides, G Tsaknis, S Kokkori, I Karampela, D Konstantonis, S Karabi, E Vrigkou, A Pappas, S Orfanos, A Armaganidis

End-expiratory esophageal pressure versus lower inflection point in acute lung injury

A Yaroshetskiy, D Protsenko, E Larin, O Ignatenko, B Gelfand

Lung recruitment induced by Sigh in hypoxemic intubated critically ill patients

TM Mauri, G Bellani, A Coppadoro, P Tagliabue, A Barletta, V Meroni, M Teggia Droghi, N Patroniti, A Pesenti

Quantification of stress raisers in ARDS

M Cressoni, M Amini, P Cadringher, C Chiurazzi, D Febres, E Gallazzi, A Marino, M Brioni, F Menga, I Cigada, E Carlesso, D Chiumello, L Gattinoni

Recruited lung tissue does not resume normal mechanical properties

M Cressoni, C Chiurazzi, M Amini, D Febres, E Gallazzi, E Carlesso, P Cadringher, T Langer, D Chiumello, L Gattinoni

Intraoperative management of hypoxemia with recruitment maneuvers: are the benefits worth the costs?

V Grosomanidis, B Fyntanidou, K Karakoulas, K Kotzampasi, E Oloktsidou, C Nouris, C Skourtis

Haemodynamic changes during alveolar recruitment manoeuvre in patients with diastolic dysfunction

A Rubino, E Marini, B Ferro, M Collareta, F Forfori, F Guarracino, F Giunta

Alveolar Recruitment for ARDS Trial: preliminary results

AB Cavalcanti, EA Suzumura, M Abreu, GF Ribeiro, A Kodama, F Moreira, HP Guimarães, E Romano, MB Amato, O Berwanger, CR Carvalho, ART Investigators

Intensive alveolar recruitment protocol reduces pulmonary complications and intensive care permanence after cardiac surgery

A Leme, L Hajjar, E Nozawa, C Hashizume, J Almeida, J Fukushima, J Auler Jr, R Santiago, R Ianotti, M Amato, E Osawa, M Feltrim, F Galas

Reliability of pressure measurements via balloon catheters is high: an evaluation of six esophageal catheters

S Walterspacher, L Isaak, HJ Kabitz, J Guttmann, S Schumann

Effect of protective ventilation on organ-specific cytokine production in an experimental postoperative sepsis model

J Sperber, M Lipcsey, A Larsson, A Larsson, J Sjölin, M Castegren

Time required for gas exchange equilibration after a change of positive end-expiratory pressure in acute respiratory distress syndrome

S Coppola, D Chiumello, F Menga, M Brioni, I Cigada, S Froio

Comparison between the standard and low-dose chest CT scans on the lung quantitative analysis in critically ill patients

S Froio, D Chiumello, I Cigada, M Brioni, S Coppola, F Menga, L Gattinoni

Preliminary experience with airway pressure release ventilation on hemodynamics in patients with septic shock in a medical/surgical ICU

A Hussain, H Lababidi, A Mir, A AlHamoud, A Al Oheli, A Al Enezi

Feasibility and effectiveness of prone position in morbidly obese ARDS patients: a case-control clinical study

A De Jong, N Molinari, M Sebbane, A Prades, S Jaber

Provision of mechanical ventilation to pregnant/postpartum women with H1N1 influenza: a case-control study

WE Pollock, R Bellomo, S Webb, I Seppelt, A Davies, E Sullivan, S Morrison, B Howe

Inhalation injury in critical burn patients

L Cachafeiro, M Sanchez, E Herrero, L Fernández, M Irazabal, M Hernandez, A Agrifoglio, A Garcia de Lorenzo, M Lendinez

Beneficial effects of intrapulmonary percussive ventilation in patients with respiratory insufficiency in the ICU

I Blum, R Janssen-Dean, A Overdijk van, B Speelberg

High-frequency ventilation for acute traumatic and nontraumatic lung injury

R Varutti, R Bigai, M Fiorillo, D Tomasello, W Mercante, G Trillò

Improvement in oxygenation with high-frequency oscillatory ventilation combined with tracheal gas insufflation is correlated to the extravascular lung water index

CS Vrettou, S Malachias, SG Zakynthinos, SD Mentzelopoulos

Physiologic effects and regional ventilation of high-frequency positive-pressure ventilation using a conventional ventilator in a severe ARDS animal model associated with an inspiratory pause or recruitment maneuvers

RL Cordioli, M Park, M Amato, S Gomes, E Leite, L Azevedo

High-frequency percussive ventilation at altitude: study in a hypobaric chamber with a mechanical test lung

AC Cirodde, S Montmerle, ND Donat, CB Bourhillon, P Jault, L Bargues, T Leclerc

Recruitable volume is comparable in acute respiratory distress syndrome and in healthy lungs

CA Stahl, K Moeller, D Steinmann, D Henzler, S Lundin, O Stenqvist

Nosocomial bloodstream infection and venovenous extracorporeal membrane oxygenation: a retrospective cohort study

B Serra de Oliveira, S Mendes Fernandes, C França

Monitoring anticoagulation during extracorporeal membrane oxygenation in patients with acute respiratory failure

M Panigada, C Mietto, F Pagan, L Bogno, V Berto, L Gattinoni

Extracorporeal membrane oxygenation: the MOTOR of cytokine production?

Y Hara, O Nishida, T Nakamura, S Uchiyama, J Shibata, C Yamashita, M Yumoto, Y Shimomura, N Kuriyama, N Yasuoka, M Ito, K Kawata, S Hayakawa, S Yamada, T Miyasho, K Moriyama

Effect of extracorporeal CO2 removal on respiratory rate in spontaneously breathing patients with chronic obstructive pulmonary disease exacerbation

E Spinelli, S Crotti, L Zacchetti, N Bottino, V Berto, R Russo, M Chierichetti, A Protti, L Gattinoni

ECCO2 removal with a phosphorylcholine-coated membrane oxygenator in difficult respiratory weaning patients

F Turani, S Martini, A Marinelli, M Falco, R Barchetta, F Candidi, F Gargano

Lung elastance can be determined without esophageal pressure measurements

C Grivans, S Lundin, O Stenqvist

Feasibility of minimally invasive stimulation of the phrenic nerves for supporting ventilation in fully anesthetized swine

J Bijwadia, M Karamanoglu

Prehospital management of COPD patients in respiratory failure and short-term outcome

G Campagne, J Cuny, P Gosselin, P Goldstein, N Assez, E Wiel

N-terminal pro-brain natriuretic peptide as a prognostic marker in patients with exacerbation of chronic obstructive pulmonary disease

P Stamatis, H Michalopoulou, D Stamatis

Novel biomarkers for prediction of mortality after acute exacerbation of chronic obstructive pulmonary disease

H Michalopoulou, H Michalopoulou, P Stamatis, F Kattis, D Stamatis

High incidence of respiratory viruses in critically ill adult patients with respiratory failure

M Sietses, TE Faber, L Bont, H Buter, EC Boerma

Role of bronchoscopy during non-invasive ventilation in hypercapnic respiratory failure

W Rady, A Abouelela, A Aly, W Youssef

SMART-COP score for patients admitted with community-acquired pneumonia (CAP) to an ICU in a district general hospital: a smarter way of identifying patients with severe CAP?

M Pachucki, F Kelly, A Padkin

Effects of steroid therapies to severe streptococcal pneumoniae that required mechanical ventilation

T Nagura, T Ikeda, K Ikeda, T Ueno, S Suda

Risk factors for ventilator-associated pneumonia in a surgical ICU

A Kundakci, O Ozkalaycı, P Zeyneloglu, H Arslan, A Pirat

Ventilation distribution measured with electrical impedance tomography at varying levels of assist during pressure support versus neurally adjusted ventilatory assist in ICU patients

MS Van Mourik, P Blankman, D Hasan, D Gommers

Analysis of bilevel positive airway pressure therapy in children based on weight

A Williams, T Abramo

Determinants of non-invasive ventilation success or failure in morbidly obese patients in acute respiratory failure

M Lemyze, P Taufour, J Mallat, O Nigeon, D Thevenin

Non-invasive ventilation in patients with a clinical diagnosis of pneumonia: a clinical audit

CJ Wright, J Hornsby, DA Barr, SR Moonesinghe

Analysis of management of non-invasive ventilation support in prehospital care for COPD patients and short-term outcome

J Cuny, G Campagne, P Gosselin, P Goldstein, N Assez, E Wiel

A window into diaphragm kinetics: feasibility, precision, and physiological meaning of ultrasound measurements of diaphragm thickness

EC Goligher, F Laghi, ND Ferguson

Retrospective review of utilisation and outcomes of diaphragmatic EMG monitoring and neurally adjusted ventilatory assist in a central London teaching hospital over a 3-year period

A Skorko, D Hadfield, A Vercueil, C Bell, A Feehan, K Peters, P Hopkins

Validation of a lung ultrasound protocol in acute respiratory failure: preliminary results

RV Cremonese, AC Tabajara Raupp, JM Stormovski de Andrade, RS Townsend, FS Neres, AS Machado, MC Prestes, JG Maccari, FLDexheimer Neto

Risk of weaning failure with PAOP ≥15 versus PAOP ≥18

Y Nassar, A Abdelbary

Impact of continuous positive airway pressure on the treatment of acute exacerbation of asthma: a randomised controlled trial

Y Sutherasan, S Kiatboonsri, P Theerawit, C Kiatboonsri, S Trakulsrichai

Novel method to confirm tracheal intubation based on airway pressures: validation in patients with lung disease

A Stemerdink, KG Monsieurs, F Luijmes, W Dieperink, JG Zijlstra, AF Kalmar

Main indications, diagnostic and therapeutic yield of bronchoscopy in the ICU

J Iglesias, B Gonzalez, O Rajas

Benchtop study comparing leakages across cuffs of three endotracheal tubes

SM Lam, CW Lau, WW Yan

Endotracheal tube with tapered-type cuff for preventing ventilator-associated pneumonia: a randomized clinical trial

N Saito, T Yagi, Y Hara, H Matsumoto, K Mashiko

Effect of body position changes on endotracheal tube cuff pressure in ventilated patients

C Lizy, W Swinnen, S Labeau, S Blot

Towards safer airway management in the critically ill: lessons from National Audit Project 4

N Santana-Vaz, S Tallowin, H Lewis, D Park, R O'Brien, JM Patel

Quantitative assessment of endotracheal tube (ETT) biofilm by micro-CT scan: evaluation of the effectiveness of ETT cleaning devices

A Coppadoro, G Bellani, T Mauri, R Borsa, V Meroni, A Barletta, M Teggia Droghi, A Lucchini, R Marcolin, N Patroniti, S Bramati, A Pesenti

Early identification of patients at risk of difficult intubation in the ICU: development and validation of the MACOCHA score in a multicenter cohort study

A De Jong, N Molinari, N Terzi, N Mongardon, B Jung, S Jaber

Incidence of major complications related to endotracheal intubation in ICUs of nonacademic Brazilian public hospitals

AB Cavalcanti, K Normilio-da-Silva, JC Acarine Mouro, F Moreira, AA Kodama, R Del-Manto, O Berwanger

Tracheal intubation for a difficult airway using Airway scope®, KingVision® and McGRATH®: a comparative manikin study of inexperienced personnel

J Itai, Y Tanabe, T Nishida, T Inagawa, Y Torikoshi, Y Kida, T Tamura, K Ota, T Otani, T Sadamori, K Une, R Tsumura, Y Iwasaki, N Hirohashi, K Tanigawal

Resistance of neonatal endotracheal tubes: a comparison of four commercially available types

J Spaeth, D Steinmann, J Guttmann, S Schumann

NT-proBNP and cardiac cycle efficiency changes during extubation process in critically ill patients

F Franchi, P Mongelli, M Cozzolino, B Galgani, C Ragozzino, C Bianchi, B Biagioli

Comparison of outcomes between early and late tracheostomy for critically ill patients

K Suzuki, S Kusunoki, T Yamanoue, K Tanigawa

Ultrasound scanning for percutaneous dilatational tracheostomy: a systematic review

R Pugh, A Slater

Evaluation of a new device for emergency transcricoid ventilation in a manikin model

P Persona, P Diana, A Ballin, F Baratto, M Micaglio, C Ori

Device for measuring bronchodilator delivery and response in resource-limited settings

CW Carspecken, D Talmor

Evidence-based guidelines and protocols for the management of adult patients with a tracheostomy: a systematic review

J Siddiqui, PB Sherren, MA Birchall

Survey of emergency tracheostomy management in the East of England region

N Lawrence, L Oakley, C Swanavelder, M Palmer

Can we keep neck breathers safe? A survey on training adequacy of medical staff caring for tracheostomy/laryngectomy patients

C Tjen, G Rajendran, S Hutchinson

Laryngeal mask as a safe and effective ventilatory device during Blue Dolphin tracheostomy in the ICU

A De Nicola, MJ Sucre, G Donnarumma, A Corcione

Real-time ultrasound-guided balloon dilatational percutaneous tracheostomy is a safe procedure in critically ill patients: an evaluation study

A Taha, A Shafie, M Mostafa, P Wallen, H Hon, R Marktanner

Right ventricular restriction in interventional lung assist for acute respiratory distress syndrome

G Tavazzi, M Bojan, S Canestrini, M White, S Price

Left ventricular electromechanical dyssynchrony and mortality in cardiothoracic intensive care

G Tavazzi, M Bojan, A Duncan, A Vazir, S Price

Safety of ultrasound-guided central venous access in critically ill patients with uncorrected coagulopathy

G Reusz, C Langer, G Egervari, P Sarkany, A Csomos

Cyanoacrylate glue prevents early bleeding of the exit site after CVC or PICC placement

G Scoppettuolo, MG Annetta, C Marano, E Tanzarella, M Pittiruti

Intracardiac ECG for confirmation of correct positioning of central venous catheters is safe and cost-effective

M Eriksson, R Dörenberg

Is automated brachial cuff measurement of arterial pressure less accurate in cases of arrhythmia?

K Lakhal, S Faiz, M Martin, AS Crouzet, F Reminiac, S Ehrmann, R Cinotti, X Capdevila, K Asehnoune, Y Blanloeil, B Rozec, T Boulain

Cardiac output monitoring in brain-stem-dead potential organ donors: an audit of current UK practice

CJ Wright, A Broderick, G Mandersloot

Indocyanine green plasma disappearance rate for assessment of liver function: re-evaluation of normal ranges and impact of biometric data

W Huber, M Kranzmayr, C Schultheiss, W Reindl, A Krug, B Saugel, U Mayr, RM Schmid

Prediction of 28-day mortality by indocyanine green disappearance rate, other markers of hepatic function and transpulmonary thermodilution parameters: a prospective study in 154 patients

W Huber, D Ertekin, T Langer, B Saugel, T Lahmer, M Messer, C Spinner, C Schultheiss, RM Schmid

Mixed and central venous oxygen saturation are not interchangeable in patients with cardiogenic shock after cardiac surgery

S Romagnoli, P Balsorano, F Landucci, A De Gaudio

Pulmonary hemodynamic disorder in pediatric sepsis and their correction with L-arginine infusion

M Georgiyants, V Korsunov

Utility of transesophageal echocardiography in the ICU: a preliminary US perspective

A Kaynar, D Phillips, H Gomez, M Lischner, S Melhem, K Subramaniam, M Pinsky

Cardiopulmonary monitoring in Thai ICUs: results of ICU-RESOURCE I surveys

K Chittawatanarat, A Wattanatham, D Sathaworn, C Permpikul

Establishing a critical care echocardiography laboratory

K Yastrebov, A McLean

Contrast-enhanced ultrasonography in the ICU: promising tool or exciting toy?

I Göcze, R Herzog, BM Graf, A Agha, HJ Schlitt, K Pfister, E Jung, T Bein

Hemodynamic disclosure of septic shock patients by intensive care ultrasound

P Theerawit, Y Sutherasan, T Hongpanat

Influence of positive end-expiratory pressure on four-chamber longitudinal strain analysis by speckle tracking echocardiography

F Franchi, A Faltoni, M Cameli, S Cecchini, M Lisi, M Contorni, S Mondillo, S Scolletta

Evaluation of a new calibration index suggesting recalibration of the pulse contour cardiac index by transpulmonary thermodilution: a prospective study

W Huber, K Waldleitner, S Mair, B Saugel, RM Schmid

Validation of less-invasive hemodynamic monitoring with Pulsioflex in critically ill patients: interim results of a multicentre study

K Van de Vijver, C Pigozzi, L Vervliet, V Vanbiervliet, V Brabers, I Vos, H Maes, N Van Regenmortel, I De laet, K Schoonheydt, H Dits, J Belda, Z Molnar, M Malbrain

Interim results of an ongoing study on the use of non-invasive hemodynamic monitoring with Nexfin in critically ill patients

K Van de Vijver, V Brabers, C Pigozzi, L Vervliet, V Vanbiervliet, H Maes, I Vos, M Peetermans, N Van Regenmortel, I De laet, K Schoonheydt, H Dits, M Malbrain

Cost-effectiveness analysis of stroke volume variation guided perioperative hemodynamic optimization

J Benes, J Zatloukal, A Simanova, I Chytra, E Kasal

EV1000/VolumeView: a new device for a more reliable measurement of extravascular lung water index in patients with lung resections

A Donati, C Melia, V Monaldi, R Domizi, E Damiani, A Carsetti, C Scorcella, R Castagnani, P Pelaia

Goal-directed resuscitation therapy in high-risk patients undergoing cardiac surgery (GRICS study): a randomized controlled trial - preliminary results

E Osawa, A Rhodes, J Vincent, J Almeida, J Fukushima, B Pileggi, C Park, L Camara, J Auler Jr, R Chan, M Piccioni, M Lima, F Galas, L Hajjar

Perioperative volume management for esophageal cancer surgery

M Karaman Ilic, G Madžarac, J Kogler, D Stančić Rokotov, N Hodoba

Treatment-related cardiac complications associated with goal-directed therapy in high-risk surgical patients: a meta-analysis

N Arulkumaran, C Corredor, M Hamilton, M Grounds, J Ball, A Rhodes, M Cecconi

Estimation of potential cost-savings related to the implementation of perioperative hemodynamic goal-directed therapy

T Simon, G Marx

Cardiac output estimation: Vigileo and Mostcare versus echocardiography

S Romagnoli, D Quattrone, AR De Gaudio

Brachial pulse waveform characteristics predict development of organ failure in septic patients

S Kazune, I Jagmane

Computerized decision support system improves consistency of haemodynamic assessment amongst ICU team members

AE Aneman, R Ranganatha

Volume quantification by contrast-enhanced ultrasound and thermodilution: an in vitro comparison

IH Herold, G Russo, HC Van Assen, HH Korsten, M Mischi

Successful introduction of cardiac index, fluid responsiveness and oxygen delivery data into the primary survey at a central London major trauma centre and impact on time to CT, fluid resuscitation and disposal

S Helyar, I De Abreu, S Holloway, P Hopkins

Fluid responsiveness in pressure support ventilation: role of asynchrony

A Messina, D Colombo, G Cammarota, M De Lucia, F Della Corte, P Navalesi

Comparison of pulse pressure variation with radial arterial systolic, diastolic and pulse transit time interval variation in pediatric patients undergoing liver transplantation

YJ Moon, IG Jun, WJ Shin, BH Sang, GS Hwang

Mini-fluid challenge: how much fluid and what parameter to use?

B Geerts, RB De Wilde, JJ Maas, LP Aarts, JR Jansen

Efficacy of intraoperatory optimisation of fluids guided with transoesophageal Doppler monitorisation: a multicentre randomised controlled trial

S Maeso, R Villalba, J Ripollés, S Asuero, J Blasco, J Calvo

Looking for the inflexion point of the Frank-Starling curve

HD Aya, M Geisen, C Ebm, N Fletcher, M Grounds, A Rhodes, M Cecconi

Prediction of stroke volume response to fluid bolus in 100 children

R Saxena, A Durward, I Murdoch, S Tibby

Microcirculatory changes during goal-directed or mean arterial pressure-guided fluid therapy in abdominal surgery

SP De Wolf, J Stens, RJ Van der Zwan, N Koning, C Boer

Postoperative imaging of the intestinal microcirculation

I Abdo, R Hall, D Henzler, V Cerny, CH Lehmann

Monitoring microcirculatory blood flow with a new sublingual tonometer in a porcine model of haemorrhagic shock

P Palagyi, J Kaszaki, Z Molnar

Sublingual microcirculatory changes during transient intra-abdominal hypertension: a study in laparoscopic surgery patients

L Maddison, K Riigor, J Karjagin, J Starkopf

Changes in microcirculatory perfusion during cardiac surgery are paralleled by alterations in glycocalyx integrity

C Boer, NJ Koning, J Van Teeffelen, AB Vonk, H Vink

Microvascular response to cold stress in healthy humans

A Pranskunas, R Rasimaviciute, J Paltanaviciute, L Daniuseviciute, V Pilvinis, M Brazaitis

Microcirculatory response to experimentally-induced whole body heat stress in healthy humans

A Pranskunas, E Milieskaite, I Maraulaite, L Daniuseviciute, Z Pranskuniene, V Pilvinis, M Brazaitis

Observational study of the effects of age, diabetes mellitus, cirrhosis and chronic kidney disease on sublingual microvascular flow

T Reynolds, S Jhanji, A Vivian-Smith, RM Pearse

Lactate clearance as a determinant of mortality in surgical patients

FF Amorim, EB Moura, AR Santana, FB Soares, LG Godoy, TA Rodrigues, LJ Almeida, GM FIlho, TA Silva, AP Amorim, JA Neto, MO Maia

Assessment of the mottling score as a mortality predictor in critically ill patients

E Bastos de Moura, F Ferreira Amorim, C Darwin Silveira, M Oliveira Maia

Impact of different haemodynamic resuscitation strategies on brain perfusion and tissue oedema markers in a model of severe haemorrhagic shock

KK Ida, DA Otsuki, LU Castro, TR Sanches, MH Shimizu, LC Andrade, JO Auler-Jr, LM Malbouisson

Accuracy of the shock index and various modified shock indexes to predict early mortality in patients suffering from gastrointestinal haemorrhage

J St-Cyr Bourque, J Cliche, J Chauny, R Daoust, J Paquet, É Piette

Inhaled carbon monoxide or nebulized sodium nitrite protect against hemorrhagic shock-induced mitochondrial dysfunction

H Gomez, D Escobar, B Ataya, L Gordon, O Ogundele, M Pinsky, S Shiva, B Zuckerbraun

Is norepinephrine more effective than other vasopressors for septic shock? A systematic review and meta-analysis

F Zhou, Z Peng, W Zhang, J Bishop, Q Song

Vasopressin Versus Norepinephrine for the Management of Shock After Cardiac Surgery (VaNCS study): a randomized controlled trial

L Hajjar, JL Vincent, A Rhodes, D Annane, F Galas, J Almeida, S Zeferino, L Camara, V Santos, J Pereira, E Osawa, E Maciel, A Rodrigues, J Jardim, D Blini, E Araujo, F Bergamin, R Kalil Filho, J Auler Jr

Intraaortic counterpulsation in a second-level institution: indications, management and outcome

R Gómez López, P Fernández Ugidos, P Vidal Cortés, M Lorenzo Lage, A Tizón Varela, E Rodríguez Álvarez

Impact of left ventricular ejection fraction and elevated filling pressures on mortality in mechanically ventilated patients in severe sepsis or septic shock

S Gillespie, J Pulido

Effect of β-blockers and calcium channel blockers on shock index predictability in patients suffering from urosepsis

J Cliche, J St-Cyr Bourque, R Daoust, J Chauny, J Paquet, E Piette

Levosimendan in critically ill adults: a utilisation review

J Aron, S Harrison, A Milne, S Patel, R Maharaj

Levosimendan versus dobutamine in Tako-tsubo cardiomyopathy

FR Righetti, MP Parolini, GC Castellano

Combined effects of ivabradine with dobutamine or levosimendan in isolated perfused hearts

D Konrad, R Vicenzi-Moser, M Vicenzi, U Aldenhoff, E Schwarzl, W Toller

Influence of temperature on the cardiac action of dobutamine and levosimendan in isolated perfused hearts

U Aldenhoff, R Vicenzi-Moser, M Vicenzi, D Konrad, E Schwarzl, W Toller

Conflicting results between V/Q SPECT and angioscan in pulmonary embolism: what to do?

JM Martel, MN Nadeau, RD Daoust, JP Paquet, JC Chauny

Intraabdominal hypertension and abdominal compartment syndrome in patients admitted to a medical and surgical ICU at a third referral university hospital

N Chindavech, S Yenarkart, S Kongsayreepong

Red cell distribution width predicts cardiovascular complications after high-risk surgery

M Geisen, HD Aya, C Ebm, MA Hamilton, J Ball, M Grounds, A Rhodes, M Cecconi

Consequences of obesity in outcomes after cardiac surgery: analysis of the ARIAM registry

EC Curiel-Balsera, J Muñoz-Bono, MJ Delgado-Amaya, R Hinojosa-Pérez, A Reina-Toral, A Gordillo-Brenes, R Rivera-Fernández

Myocardial injury in critically ill patients admitted with noncardiac diagnoses

J Lo, K Lei, I Webb, J Coutts, J Chambers, A Griffiths, J Smith, E Connell, P Collinson, J Peacock, D Treacher, M Ostermann

Validation of the GRACE score risk in our population

L Sayagues, J Sieira, E Abbu, J Chico, C Pena, J Gonzalez Juantey

Outcomes of incomplete and complete revascularization in ACS

L Sayagues, J Sieira, E Abbu Assi, J Chico, C Pena, J Gonzalez Juanatey

Non-invasive valve implantation with TAVI versus conventional aortic valve replacement

E Trujillo-García, C Joya-Montosa, MJ Delgado-Amaya, E Curiel-Balsera

Time to recover from shock is determinant of a positive fluid balance in septic shock

S Lobo, AL Cunha

Lactate clearance is a predictor of sustained bleeding in emergency room patients with moderate upper gastrointestinal bleeding

T Wada, A Hagiwara, N Yahagi, A Kimura

Muscular glucose assessed by microdialysis and blood glucose can predict mortality in septic shock

A Massoudi, M Belhadj Amor, C Romdhani, A Ben Gabsia, I Labbene, M Ferjani

Constipation in critically ill patients and its relationship to feeding and weaning from respiratory support

E Spodniewska, A Guha

Nasogastric tube dislodgement: a problem on our ICU

B Morton, R Hall, T Ridgway, O Al-Rawi

Handling of dietary protein in critically ill patients

F Liebau, O Rooyackers, L Van Loon, J Wernerman

Confirmation of nasogastric tube placement in critical care

M Moore, R Thomson

pH testing to confirm nasogastric tube position on the ICU: are we wasting our time?

P Temblett, S George

Selenium levels in patients with different sources of sepsis

L French, P Temblett

Is a combined i.v. and enteral glutamine regimen superior to a single i.v. glutamine regimen in severe thoracic trauma?

D Pavelescu, I Grintescu, I Luca-Vasiliu, L Mirea

Clinical effect of altered lipid emulsion composition containing fish oil in postoperative patients following abdominal surgery: a prospective, randomized, open-label, comparative, multicenter phase 3 clinical study

M Keum, S Hong, H Han, D Yoon, J Seo, I Yun

Influence of fat-based versus glucose-based enteral nutrition formulas on glucose homeostasis

M Wewalka, A Drolz, C Zauner

Effect of hypocaloric versus normocaloric parenteral nutrition on whole body protein kinetics in critically ill neurosurgical patients

O Rooyackers, A Berg, J Wernerman

Withholding parenteral nutrition for 1 week reduces ICU-acquired weakness

G Hermans, B Clerckx, T Vanhullebusch, F Bruyninckx, M Casaer, P Meersseman, D Mesotten, S Vancromphaut, P Wouters, R Gosselink, A Wilmer, G Van den Berghe

Impact of early parenteral nutrition on muscle and adipose tissue compartments during critical illness

L Langouche, MP Casaer, W Coudyzer, D Vanbeckevoort, B De Dobbelaer, FG Güiza, PJ Wouters, D Mesotten, G Van den Berghe

Withholding parenteral nutrition during the first week of critical illness increases plasma bilirubin but lowers the incidence of cholestasis and gallbladder sludge

YM Vanwijngaerden, L Langouche, M Gielen, Y Debaveye, M Casaer, C Liddle, S Coulter, R Brunner, P Wouters, A Wilmer, G Van den Berghe, D Mesotten

Impact of early parenteral nutrition on catabolism

J Gunst, I Vanhorebeek, MP Casaer, G Hermans, PJ Wouters, J Dubois, K Claes, M Schetz, G Van den Berghe

Impact of early versus late parenteral nutrition on morphological and molecular markers of atrophy and autophagy in skeletal muscle of critically ill patients

I Vanhorebeek, MP Casaer, F Güiza, S Derde, I Derese, PJ Wouters, Y Debaveye, J Gunst, G Hermans, G Van den Berghe

Impact of closing an emergency department on a neighbouring teaching hospital: the concentrate effect

J Millar, R Wilson, P O'Connor, R McLaughlin

Overcrowding estimation in the emergency department: is the simplest score the best?

V Winkin, V Pinckaers, V D'Orio, A Ghuysen

GP-led walk-in centre in the UK: another way for urgent healthcare provision

M Arain, J Nicholl, M Campbell

Establishing a new emergency department: effects on patient flow

V Rautava, T Valpas, M Nurmikari, A Palomäki

Prehospital EKG evaluation in Rio de Janeiro ambulances

RV Vasconcellos, FE Erthal, RV Vargas

Technique of ultrasound-guided peripheral venous access in the emergency room

MG Annetta, G Scoppettuolo, M Biancone, F Toni, M Pittiruti

FIB the fractured femur

H Shahzad, M Majeed, D Yeo, V Gupta, U Salanke

Abdominal pain in adolescent females: a single-centre audit and review of management

F Gallagher, H Jahn, F Davies

Multidisciplinary approach to improving documentation of visual acuity in patients presenting with ocular trauma

L Low, M Johnston

BiPAP for treating moderate and severe asthma exacerbations in a PED

A Williams, T Abramo

Report of an outbreak of toxicity from a novel drug of abuse in the UK: Eric-3

C Morden, S Haig, C Kelly

Abstract withdrawn

Thallium group poisoning incident in Japan 2011

Y Namba, R Suzuki, J Sasaki, M Takayasu, K Watanabe, D Kenji, M Hayashi, Y Kitamura, M Kawamo, H Masaki, E Kyuuno, M Hayashi, M Yamaguchi, A Maeda

Heart rate variability in children with tricyclic antidepressant intoxication

EC Dinleyici, Z Kilic, S Sahin, R Tutuncu-Toker, M Eren, ZA Yargic, P Kosger, B Ucar

Diagnosing anisakiasis in the emergency department

T Takabayashi, S Ishimatsu, N Otani, T Mochizuki, R Miyamichi

Factors involved in ICU mortality following medical retrieval: identifying differences between ICU survivors and nonsurvivors

M Kennedy, P Visser, L Harriss

Safety standards for intrahospital transfer of critical care patients

D Ashton-Cleary

Prehospital hyperoxemia does not influence the functional neurological outcome in polytraumatized patients with traumatic head injury

V Vujanovic Popovic, T Pelcl, M Spindler, Z Klemenc Ketis, M Strnad

Single-dose estrogen infusion can amplify brain levels of Sonic hedgehog, a signal protein for neuro stem cells and repair following the indirect brain injury resulting after severe torso burns

PE Pepe, JG Wigginton, JW Gatson, J Simpkins, D Maass, K AbdelFattah, AH Idris, V Warren, JP Minei

Feasibility and experience of using exception from informed consent in a pilot study of immediate estrogen infusion for hypotensive trauma patients

JG Wigginton, PE Pepe, V Warren, K AbdelFattah, JW Gaston, J Simpkins, JP Minei, D Maass, AH Idris

Early administration of a single dose of parenteral estrogen decreases inflammation in the heart for 45 days after severe burns

PE Pepe, JG Wigginton, JW Gatson, AH Idris

Level of lipopolysaccharide-binding protein and microbial landscape with account of severity of sepsis syndromes in polytrauma

IM Ustyantseva, OI Khokhlova, OV Petukhova, YA Zhevlakova

Risk factors for the development of complications following blunt chest trauma: a new risk stratification tool

C Battle, H Hutchings, S Lovett, P Evans

Guidelines for chest drain insertion do not protect relevant anatomical structures

J Bowness, P Kilgour, S Whiten, I Parkin, J Mooney, P Driscoll

Prediction score of indications for whole body computed tomography in blunt trauma patients

H Oda, R Sasaki, A Hagiwara, A Kimura

Prehospital blood transfusion: 5-year experience of an Australian helicopter emergency medical service

PB Sherren, B Burns

Severe hyperkalemia is prevalent and can be detected by quantitative electrocardiographic findings and medication history of calcium channel blocker among the patients with symptomatic or extreme bradycardia

SB Chon

Prehospital risk stratification following out-of-hospital cardiac arrest

Y Goto, T Maeda, Y Goto

Multidisciplinary Medical Emergency Team System increases survival in cancer patients undergoing cardiopulmonary resuscitation

L Hajjar, F Galas, S Vieira, J Almeida, E Osawa, C Park, J Fukushima, E Angelo, A Pinheiro, J Auler Jr

Focused cardiac ultrasound in resuscitation

E Fish, L Fuchs, G Gulati, D Talmor, A Oren-Grinberg

Acute intrathoracic gastric herniation as a rare cause of cardiac arrest

DW Hoelen, AL Van Duijn, CL Meuwese, JP Ruurda, MA Sikma

Implementation of dispatcher-assisted cardiopulmonary instructions using the ALERT protocol: preliminary results in Belgium

A Ghuysen, S Stipulante, M El Fassi, A Donneau, V D'Orio, R Tubes

Prehospital epinephrine administration and survival among patients with unshockable initial rhythm after out-of-hospital cardiac arrest

Y Goto, T Maeda, Y Goto

Impact of termination of resuscitation for out-of-hospital cardiopulmonary arrest in Japan

T Fukuda, N Ohashi, M Gunshin, T Matsubara, S Nakajima, Y Kitsuta, N Yahagi

Survival from cardiopulmonary arrest after regular working hours in a tertiary-care hospital: retrospective study

A Mir, A Hussein, A AlEnezi, M Almaani, M Shah, A Shah, B Daoud

Infrared pupillometry for outcome prediction after cardiac arrest and therapeutic hypothermia

T Suys, N Sala, AO Rossetti, M Oddo

Effect of moderate hyperventilation and induced hypertension on cerebral tissue oxygen saturation in comatose post-cardiac arrest patients treated with hypothermia

T Suys, N Sala, M Oddo

Predictive ability of the IMPACT-TBI prognostic model is improved by adding markers of coagulation

R Raj, J Siironen, R Kivisaari, L Handolin, J Hernesniemi, M Skrifvars

Nonischemic endogenous lactate production in humans with severe traumatic brain injury

N Sala, T Suys, JB Zerlauth, J Bloch, P Magistretti, R Meuli, M Oddo

Japan Coma Scale used in the prehospital setting can predict clinical outcome in severe pediatric trauma

T Yagi, N Saito, Y Hara, H Hisashi Matumoto, K Mashiko

Effect of positive end-expiratory pressure on ultrasound measurement of optical sheath nerve diameter: preliminary study

T Aslanidis, E Anastasiou, E Geka, E Efthimiou, A Myrou, A Kontos, D Papadopoulos, E Boultoukas, M Giannakou-Peftoulidou

National survey of current protocols and management of the traumatic brain injury patients in UK ICUs

B Lewinsohn, S Panchatsharam, S Wijayatilake, A Billini, G Delacedra, R Jain, J Khan, R Shetty, A Lewinsohn

Low-frequency autoregulation index for calculation of optimal cerebral perfusion pressure in severe traumatic brain injury

F Guiza, G Meyfroidt, M Schuhmann, G Van den Berghe, I Piper, B Depreitere

Cerebral rSO2 monitoring in pediatric altered mental status patients

T Abramo, I Kane

Intravenous paracetamol for fever control in acute brain-injured patients: cerebral and hemodynamic effects

E Picetti, I Rossi, P Ceccarelli, S Risolo, P Schiavi, V Donelli, A Crocamo, M Antonini, M Caspani

Retrospective analysis of the hemodynamic effects of induction of barbiturate coma in patients with refractory elevated intracranial pressure

S D'Hollander, M Vander Laenen, JB Gillet, C De Deyne, R Heylen, W Boer, F Jans

Hospital readmissions following traumatic brain injury

A Boutin, K Francisque, L Moore, F Lauzier, X Neveu, A Turgeon

Risk factors of pituitary disorders following traumatic brain injury

F Lauzier, O Lachance, I Cote, B Senay, P Archambault, F Lamontagne, A Boutin, M Shemilt, L Moore, F Bernard, C Gagnon, D Cook, AF Turgeon

Vasopressin reduces the cumulative epinephrine dose in hypothermic swine with traumatic brain injury

AD Goldberg, MG Kashiouris, L Keenan, A Rabinstein, M Kumar

Long-term functional outcome in adults with severe TBI: a meta-analysis

M Asselin, Y Lachance, G Lalonde, A Boutin, M Shemilt, L Moore, F Lauzier, R Zarychanski, P Archambault, F Lamontagne, D Fergusson, A Turgeon

Monitoring of severe traumatic brain injury patients in UK ICUs: a national survey

S Panchatsharam, B Lewinsohn, G De La Cerda, D Wijayatilake

Survival analysis after head injury: is a normal INR reassuring?

K Leclerc-Gagne

One-year extended Glasgow Outcome Scale and hospital mortality predictors in patients with severe traumatic brain injury in Brazil

R Turon, FR Ferreira, D Prado, P Kurtz, M Damasceno

Early respiratory deterioration predicts poor outcome after aneurysmal subarachnoid hemorrhage

E Van Lummel, L Vergouw, M Van der Jagt

Evaluation of proximal-distal velocity gradient in spastic middle cerebral artery after aneurismal subarachnoid hemorrhage

M Gotti, F Stretti, S Pifferi, V Conte, M Zara, N Stocchetti

Microparticles in aneurismal subarachnoid hemorrhage: role in acute and delayed cerebral ischemia

V Conte, A Artoni, S Magnoni, M Leoni, L Capuano, V Civelli, N Stocchetti

Intracranial pressure after subarachnoid hemorrhage

A Lombardo, T Zoerle, ER Zanier, L Longhi, N Stocchetti

Prevalence of pituitary disorders associated with aneurysmal subarachnoid hemorrhage

F Lauzier, I Cote, A Bureau, M Shemilt, A Boutin, L Moore, C Gagnon, AF Turgeon

Correlation between the timing of endovascular coiling or microsurgical clipping and long-term outcomes of patients after aneurysmal subarachnoid haemorrhage

N Ojukwu, R Jain, S Wijayatilake, A Bellini, R Shetty, J Khan, G De la Cerda

Time course of neuropsychological functioning after aneurysmal subarachnoid hemorrhage

B Zarino, G Bertani, V Conte, S Magnoni, A Di Cristofori, N Stocchetti

Neuroprotective effect of a new synthetic aspirin-decursinol adduct in a rat model of ischemic stroke

YH Lee, CW Park, JH Cho, MH Won

Prevalence of acute critical neurological disease in children: a global epidemiological assessment (PANGEA)

E Fink, R Tasker, J Beca, MJ Bell, RS Clark, J Hutchison, M Vavilala, RS Watson, L Weissfeld, PM Kochanek, DC Angus, PANGEA Investigators

Survival analysis of patients taking dabigatran who consulted an emergency department for acute bleeding: a first alarm

OA Arlet, EN Notebaert, JP Paquet, RD Daoust, MV Vincent, JC Chauny

Bedside anti-Xa measurement for therapeutic assessment of a prophylactic anticoagulation regimen

B Dewulf, I Herck, F De Somer, K Francois, J Decruyenaere

Effective dosage of enoxaparin for intensive care patients

S Robinson, A Zincuk, U Larsen, P Toft

Abstract withdrawn

Anti-Xa activities following 5,000 IU and 7,500 IU of s.c. dalteparin in critically ill patients and 5,000 IU in medical patients: a prospective randomized study

GH Heinz, U Priglinger, I Pabinger

Randomized double-blind placebo-controlled PK/PD study on the effects of a single intravenous dose of the anti-hepcidin Spiegelmer NOX-H94 on serum iron during experimental human endotoxemia

L Van Eijk, DW Swinkels, A John, F Schwoebel, F Fliegert, L Summo, S Vauleon, JM Laarakkers, K Riecke, P Pickkers

Haemoglobin concentration on admission to intensive care influences hospital mortality rates and length of stay: a retrospective study

M Adams, P Dean, P Doherty, S Noble, A Mackay

Influence of epidural anesthesia on the hemocoagulation disorders and quantity of septic complications in patients with acute necrotizing pancreatitis

O Tarabrin, S Shcherbakov, A Tkachenko, O Kushnir, I Grychushenko

Hemoviscoelastography: a new method of hemostasis monitoring

O Tarabrin, S Galich, D Gavrychenko, G Mazurenko, A Suhanov

Thromboelastographic monitoring of fondaparinux in surgical patients

B Martinez, R Giacomello, R Paniccia

Urokinase-induced fibrinolysis in thromboelastography (UKIF-TEG) to assess fibrinolysis in critically ill patients

L Zacchetti, M Panigada, M Cressoni, T Marchesi, L Gattinoni

Bleeding complications after central line insertions and the relevance of pre-procedure coagulation tests and blood component therapy

TK Kander, US Schött

Efficacy of tranexamic acid in decreasing blood loss during cesarean section

V Zaporozhan, O Tarabrin, D Gavrychenko, G Mazurenko, O Saleh, I Lyoshenko

In vitro correction of hypothermic and dilutive crystalloid andcolloid rotational thromboelastography-monitored coagulopathywith fi brinogen and factor XIII

D Winstedt, O Thomas, US Schött

Dose-response of fibrinogen and factor XIII concentrate for correcting albumin-induced coagulopathy

US Schött, DW Winstedt, JH Hanna

Intraoperative cell savage for life-threatening haemorrhagic caesarean section

AS Ducloy, C Barre-Drouard, E Jaillette, S Depret-Mosser, B Wibaut, B Vallet, S Susen

Does protamine infusion reduce postoperative blood loss and heparin rebound in cardiac surgery patients? A retrospective analysis of 240 patients on the cardiac ICU

E Helme, H Meeran, N Al-Subaie

Transfusion Requirements in Surgical Oncology Patients (TRISOP): a randomized, controlled trial

J Almeida, F Galas, E Osawa, J Fukushima, S Moulin, C Park, E Almeida, S Vieira, J Vincent, A Rhodes, M Balzan, J Inacio, H Palomba, R Nakamura, F Bergamin, A Sandrini, U Ribeiro Jr, J Auler Jr, L Hajjar

Red blood cell transfusion is a predictor of mortality and morbidity in children undergoing cardiac surgery

C Colognesi, R Maia, L Hajjar, F Bergamin, J Fukushima, E Osawa, J Almeida, L Camara, S Zeferino, V Guimaraes, F Galas

Red blood cell transfusion results in worse outcomes in patients with left ventricular dysfunction undergoing on-pump cardiac surgery

R Miadda, C Colognesi, L Hajjar, M Sundin, L Camara, S Zeferino, F Bergamin, A Leme, V Guimaraes, F Galas

Defining the need for a massive transfusion in severe blunt traumatic patients

T Umemura, H Ishikura, Y Nakamura, K Hoshino, T Nishida, T Kamitani

Association between red blood cell transfusions and clinical outcome in critically ill children

P Demaret, M Tucci, T Ducruet, H Trottier, J Lacroix

Microcirculation and blood transfusions during sepsis: leukoreduced (LR) versus non-LR red blood cells

A Donati, E Damiani, R Domizi, C Scorcella, A Carsetti, S Tondi, R Castagnani, N Mininno, P Pelaia, C Ince

Massive blood transfusion for obstetric haemorrhage

S Simmons, WE Pollock, L Phillips, S McDonald

Blood transfusion practices in the ICU of a level 1 trauma centre and tertiary cardiac unit

Y Mustafa, B Pouchet

C1 inhibitor attenuates pulmonary inflammation in an in vivo model of transfusion-related acute lung injury

M Müller, PR Tuinman, G Jongsma, AM Tuip-de Boer, L Boon, SS Zeerleder, NP Juff ermans

Incidence, risk factors and outcome of TRALI after cardiac surgery

A Dijkhuizen, R De Bruin, S Arbous

Albumin-induced coagulopathy is less severe and more effectively reversed with fibrinogen concentrate than is synthetic colloid-induced coagulopathy

DW Winstedt, JH Hanna, US Schött

Network meta-analysis of clinical trials of fluid treatments in sepsis demonstrates improved survival with albumin compared with crystalloid and hydroxyethyl starch

M Bansal, A Farrugia, G Martin

Assessing the economic impact of catheter-related bloodstream infections when switching from open to closed system delivery of human albumin solutions in ICUs

F Axelsen, P Riss

Comparing the hemodynamic effects of six different colloids

N Kteniadakis, V Grosomanidis, E Oloktsidou, B Fyntanidou, C Nouris, K Kotzampasi, D Vasilakos

Strong ion difference and arterial bicarbonate concentration as cornerstones of the impact of fluid therapy on acid-base balance

D Ottolina, M Ferrari, L Zazzeron, E Scotti, M Stanziano, C Rovati, C Marenghi, L Gattinoni, P Caironi

Microcirculatory response to fluid challenge: should we prefer balanced colloids to rebalance tissue perfusion?

A Donati, E Damiani, R Domizi, C Scorcella, A Carsetti, S Tondi, R Castagnani, N Mininno, V Monaldi, P Pelaia

Procedural sedation in the emergency department

MS Shah, FS Shah, KP Pope, AS Abbas

Impact of an age, kidney and liver function adjusted sedation protocol in critically ill patients

S Haddad, H Tamim, C Gonzales, A Rishu, A Deeb, Y Arabi

Risk and benefit of protocol sedation and daily interruption of sedation for mechanically ventilated patients: a systematic review

K Hosokawa, M Egi, M Nishimura

Chemical and physical compatibility of continuous intravenous drug infusion combinations used in paediatric intensive care

C Cole, A Fox, M Van Der Merwe, L Dickson, K Ball, A Bevan, A Hocking, J Pappachan

Abstract withdrawn

Benzodiazepines induce hyperglycemia in rats by affecting peripheral disposal of glucose

VS Salice, FV Valenza, MP Pizzocri, LV Valenti, GC Chevallard, MU Umbrello, SG Gatti, SF Fargion, GI Iapichno, LG Gattinoni

Prolonged sedation in ARDS patients with inhaled anesthetics: our experience

S Redaelli, P Mangili, V Ormas, S Sosio, L Peluso, F Ponzoni, N Patroniti, A Pesenti

Involvement of mitochondrial ATP-sensitive K+ channels in fentanyl-induced mitochondrial dysfunction of cultured human hepatocytes

S Djafarzadeh, M Vuda, J Takala, SM Jakob

Effects of clonidine on microcirculatory alterations during endotoxemia

K Schmidt, C Philipsenburg, A Zivkovic, S Hofer

Conjunctival administration of S+ketamine in rabbits

L Hess, J Malek, A Kurzova, Z Simunkova, M Votava

Use of propofol for procedural sedation reduces length of stay in the emergency department

J Millar, F Adamson, P O'Connor, R Wilson, E Ferrie, R McLaughlin

Pre-PRIS? Prospective monitoring for early markers of propofol infusion syndrome

M Stovell, S Smith, M Udberg, W Loh, P Nair

Safety profile of 1,008 cases of propofol sedation in the emergency department

S Bradburn, G Lloyd, B Newstead

Use of physical restraint in Dutch ICUs: prevalence and motives

RJ Raijmakers, RL Vroegop, H Tekatli, M Van den Boogaard, AW Van der Kooi, AJ Slooter

Factors influencing the use of physical restraints in Canadian ICUs

B Sneyers, E Luk, M Perreault, D Williamson, L Rose, S Mehta, L Burry

Current practices in ICU delirium management: a prospective multicenter study in the Netherlands

Z Trogrlic, E Ista, A Slooter, J Bakker, M Van der Jagt

Intraoperative dexamethasone and delirium after cardiac surgery: a randomized clinical trial

AC Sauër, AJ Slooter, DS Veldhuijzen, MM Van Eijk, D Van Dijk

Current perspectives, beliefs and practices concerning delirium in critically ill patients: a multicenter survey among Dutch healthcare professionals

Z Trogrlic, M Van der Jagt, P Van der Voort, J Bakker, E Ista

International validation of the delirium prediction model for ICU patients (PREDELIRIC): a multicenter observational study

M van den Boogaard, L Schoonhoven, E Maseda, C Plowright, C Jones, A Luetz, PV Sackey, P Jorens, LM Aitken, F van Haren, JG van der Hoeven, P Pickkers

Delirium in ICU patients is associated with increased temperature variability

AW Van der Kooi, TH Kappen, RJ Raijmakers, IJ Zaal, AJ Slooter

Long-term outcome of delirium in critically ill patients

A Wolters, D Van Dijk, O Cremer, D De Lange, A Slooter

Gastrointestinal symptoms in the ICU: a comparison of primary and secondary acute gastrointestinal injury

A Reintam Blaser, J Starkopf

Effects of proton pump inhibitor versus H2-receptor antagonist stress ulcer prophylaxis on ventilator-associated pneumonia: a pilot study

JF Fogas, KK Kiss, FG Gyura, ZT Tóbiás, ZM Molnár

Early diagnosis of liver failure in septic patients using the maximal liver function capacity test (LiMAx test): comparison with conventional methods

M Kaffarnik, M Stockmann, J Lock

Impact of liver resection on portal venous pressure and renal function

P Biesenbach, T Grünberger, B Payer, A Ferlitsch, W Druml, E Fleischmann, F Luf, J Mühlbacher

Value of the preoperative Model for End-stage Liver Disease score in predicting postoperative outcome in living donor liver transplantation recipients

Y Nassar, K Omar, A Battah, A Mwafy

Does just fungal evidence increase the mortality of critically ill patients with liver cirrhosis? A retrospective analysis

T Lahmer, U Mayr, M Messer, B Saugel, C Schultheiss, R Schmid, W Huber

Predictors of persistent organ failure in ICU patients with severe acute pancreatitis

I Aleksandrova, M Ilynskiy, S Rei, V Kiselev, G Berdnikov, L Marchenkova

Increased plasma levels of thrombopoietin in patients with severe acute pancreatitis

L Pigozzi, O Bosco, B Vizio, M Loiacono, M Lucchiari, G Mengozzi, C Moiraghi, G Montrucchio, E Lupia

Severe renal dysfunction measured by pRIFLE in children is an independent factor associated with death and not predicted by PIM2

J Piva, P Lago, G Pedro, F Cabral

Thorough evaluation for the new acute kidney injury criteria by Kidney Disease Improving Global Outcomes

J Izawa, S Uchino, T Fujii, T Arii, T Fukushima, S Kawano

Urinary neutrophil gelatinase-associated lipocalin as an early predictor of acute kidney injury in cardiac surgery patients

T García Rodríguez San Miguel

Atrial natriuretic peptide attenuates metabolic acidosis and inflammation of the kidney, lung and heart in a rat model of renal ischemia-reperfusion injury

M Khin Hnin Si, C Mitaka, M Tulafu, S Abe, S Ikeda

Perioperative sodium bicarbonate to prevent acute kidney injury after cardiac surgery: a multicenter double-blind randomized controlled trial

A Haase-Fielitz, M Haase, M Plass, P Murray, M Bailey, R Bellomo, S Bagshaw

Tubular damage biomarkers linked to inflammation or iron metabolism predict acute kidney injury

A Haase-Fielitz, S Westphal, R Bellomo, P Devarajan, M Westerman, P Mertens, M Haase

Renal response and acid-base balance alterations during furosemide administration

L Zazzeron, D Ottolina, E Scotti, M Ferrari, M Stanziano, C Rovati, F Zadek, C Marenghi, L Gattinoni, P Caironi

Red cell distribution width is not a predictor of mortality in acute kidney injury

P Purvis, J Kinsella, R Docking

Value of Tc-99m DMSA renal scan in assessing the prognosis and outcome of acute renal failure due to sepsis

S Fawzi, K Mashour, A Amin, H Gamal

Estimated glomerular filtration rate based on hospital discharge creatinine may significantly overestimate renal function and underestimate chronic kidney disease in survivors of critical illness

I Kolic, J Purdell-Lewis, CJ Kirwan, JR Prowle

Varying models of intra-abdominal hypertension and their effect on renal function in a porcine model

R Wise, R Rodseth, I De Laet, L Luis, L Correa-Martin, M Garcia, G Castellanos, M Malbrain

Urinary chitinase 3-like 1, a novel biomarker for acute kidney injury in adult cardiac intensive care patients: a pilot study

J De Loor, E Hoste, I Herck, K Francois, L De Crop, C Clauwaert, K Demeyere, E Meyer

Use, type and duration of cardiopulmonary bypass are related to acute kidney injury occurrence and urinary NGAL concentrations

T García Rodríguez San Miguel

Symmetrical dimethylarginine is a more sensitive biomarker of renal dysfunction than creatinine

JJ Dixon, K Lane, RN Dalton, IA MacPhee, BJ Philips

Prognostic value of neutrophil gelatinase-associated lipocalin and transpulmonary thermodilution-derived parameters within 48 hours after admission

W Huber, J Rauch, B Saugel, S Mair, M Messer, T Lahmer, C Schultheiss, P Luppa, RM Schmid

Assessment of neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury in acute heart failure patients

H Michalopoulou, H Michalopoulou, P Stamatis, J Xenogiannis, D Stamatis

Neutrophil gelatinase-associated lipocalin predicts postoperative fluid overload after cardiac surgery

M Haase, P Devarajan, P Michael, R Bellomo, A Haase-Fielitz

Survivors of acute kidney injury requiring renal replacement therapy rarely receive follow-up: identification of an unmet need

CJ Kirwan, R Taylor, JR Prowle

Aetiology and outcomes for dialysis-dependent acute kidney injury patients on the ICU

M Hameed, P Carmichael

Efficiency of substitutive renal therapy in the complex intensive care of multiple organ failure in patients with polytrauma

S Kravtsov, A Shatalin, V Agadzhanyan, D Skopintsev

Can treatment with the molecular adsorbent recirculation system be the solution for type-1 hepatorenal syndrome?

L Lavayssiere

Effect of continuous high-volume hemofiltration on patients with acute respiratory distress syndrome

A Kuzovlev, E Tishkov, O Bukaev

Dialyzer clearance of myoglobin with middle molecule filter and low blood flow CVVHD in patients with rhabdomyolysis-associated acute kidney injury

I Leppanen, T Ahonen, J Tenhunen

Daily fluid balance predicts hospital mortality in critically ill patients receiving continuous renal replacement therapy

M Kashiouris, A Akhoundi, S Chaudhary, V Velagapudi, A Goldberg, K Kashani

Fluid balance and renal outcomes in patients requiring renal replacement therapy in the ICU

JA Silversides, R Kuint, R Pinto, R Wald, M Hladunewich, NK Adhikari

Pharmacokinetics and pharmacodynamics of esomeprazole and ranitidine during continuous venovenous hemodiafiltration

V Fuhrmann, P Schenk, W Jaeger, M Miksits, R Kitzberger, U Holzinger, C Madl

Pharmacokinetics of gentamicin and vancomycin during continuous venovenous hemofiltration in critically ill septic patients with acute kidney injury

N Petejova, J Duricova, A Martinek, J Zahalkova

Effects of two different regional citrate anticoagulation CVVH protocols on acid-base status and phosphate supplementation

S Morabito, V Pistolesi, V Pistolesi, L Tritapepe, L Tritapepe, E Vitaliano, E Vitaliano, L Zeppilli, L Zeppilli, F Polistena, F Polistena, E Fiaccadori, E Fiaccadori, A Pierucci, A Pierucci

Abstract withdrawn

Muscle wasting in the ICU can be reliably monitored using ultrasound

H Jørgensen, B Nedergaard, T Gilsaa

Critical illness induces nutrient-independent adipogenesis and accumulation of alternatively activated tissue macrophages

M Marques, S Vander Perre, A Aertgeerts, S Derde, F Guiza, M Casaer, G Hermans, G Van den Berghe, L Langouche

Abstract withdrawn

Hypocalcemia during magnesium therapy for obstetric ICU admissions

PD Levin, A Szalat, M Vizana, CL Sprung, R Zaguri, Y Haviv

Hyponatremia and intensive care outcome

P Dean, R Docking, D Govenden, A Davidson, A Mackay

Strong ion gap can be accurately estimated with a simple bedside equation

L Busse, L Chawla, R Panchamia, D Choi, E Nobakht, E Brasha-Mitchell, M Seneff

Relative adrenal insufficiency in burns

A Mokline, L Gharsallah, I Rahmani, H Oueslati, B Gasri, S Tlaili, R Hammouda, A Ksontini, A Ghanem, AA Messadi

Albumin-adjusted calcium concentration should not be used to identify hypocalcaemia in critical illness

T Steele, R Kolamunnage-Dona, C Downey, C Toh, I Welters

Vitamin D status and overall and sepsis mortality in critically ill patients

P Zajic, C Schnedl, T Valentin, A Grisold, A Holl, S Farzi, S Fruhwald, H Dobnig, TR Pieber, K Amrein

Etiology of low testosterone levels in male patients with severe sepsis requiring mechanical ventilation

A Bech, H Van Leeuwen, H De Boer

Efficacy of calcium replacement in hypocalcaemia

H Chatha, K Sim

Endogenous melatonin in critically ill patients

VS Salice, IG Galluccio, BS Salihovic, IP Piva, FM Marazzo, CV Villa, MT Taverna, MU Umbrello, GM Mistraletti, GI Iapichino

Succinate ameliorates mitochondrial oxygen consumption of metformin-intoxicated human platelets

A Protti, M Monti, A Lecchi, A Artoni, N Greppi, L Gattinoni

Does chronic metformin therapy offer cardiomyoprotection in coronary artery bypass grafting surgery patients? A case-control study

A Delaporte, JP Hacquebard, P Origer, I Pastijn, M Maatouk, O Germay, E Stevens, P Kapessidou, A Roman

Metformin-associated lactic acidosis: risk factors and prognostic factors

V Di Falco, A Milano, M Battilana, F Araosta, A Grosso, D Albanese, F Petrini, L Di Liberato

Multiscale modeling of acute insulin resistance in critical care

A Pritchard-Bell, G Clermont, B Yegneswaran, R Parker

Impact of a real-time electronic persistent hyperglycemia alert on glucose control in the ICU

K Colpaert, S Oeyen, T van den Driessche, C Danneels, J Decruyenaere

Individualized targeted glucose control to avoid hypoglycemia

SP Gawel, G Clermont, T Ho, BM Newman, B Yegneswaran, RS Parker

Hyperglycemia in intensive care identifies patients at high risk of developing diabetes: preliminary data of a multicentre study

E Lukic, I Gornik, M Grgic-Medic, D Milicic, V Vegar, V Ivancan, M Peric, V Gasparovic, I Pavlic Renar

Association between average glucose levels and hospital mortality among critically ill patients

B Yegneswaran, R Parket, S Gawel, A Pritchard-Bell, T Ho, G Clermont

Continuous glucose monitoring in critically ill adults: comparison of two different calibration protocols

L Leelarathna, S English, H Thabit, K Caldwell, J Allen, K Kumareswaran, M Wilinska, M Nodale, J Mangat, M Evans, R Burnstein, R Hovorka

Root cause analysis of hypoglycemic events in critically ill patients

A McDonald, J Krinsley

Continuous arterial and venous glucose monitoring by quenched chemical fluorescence in ICU patients after cardiac surgery

S Bird, L Macken, O Flower, F Bass, N Hammond, S Webb, N Kennedy, A Baker, E Yarad, C Chau, M Librande, P Strasma, S Finfer

Performance of the Medtronic Sentrino® continuous glucose management system in the cardiac ICU

M Kosiborod, R Gottlieb, J Sekella, D Peterman, A Grodzinsky, P Kennedy, M Borkon

Intensive insulin therapy in critically ill children: impact on blood glucose dynamics and its relation with mortality

M Van Tornout, M Gielen, T Van Herpe, D Vlasselaers, L Desmet, I Vanhorebeek, G Van den Berghe, D Mesotten

Implementation of evidence-based protocols improves survival: a 15-year surgical ICU experience in 10,172 patients

SA Nasraway

Decubitus ulcers are associated with prolonged length of stay in critically ill patients

WT McGee, BH Nathanson, E Lederman, TL Higgins

HIV patients admitted to an ICU of a university hospital - experience of 15 years: 1995 to 2009

A Agrifoglio, M Arce, M Hernández, P Millan, C Guallar, I Pozuelo, M Jiménez

Prevalence and prognosis of organ dysfunctions of AIDS critically ill patients

AJ Japiassu, RA Amâncio, D Medeiros, EM Mesquita, EM Motta, FA Bozza

Mortality predictors in septic HIV patients in the ICU

P Vidal-Cortés, P Lameiro-Flores, A Aller-Fernández, M Mourelo-Fariña, P Fernández-Ugidos, R Gómez-López, M Alves-Pérez, E Rodríguez-García

Outcome of intensive care treatment for lung cancer patients

L Hajjar, F Galas, D Goto, A Tavares, M Santos, A Freitas, T Oliveira, P Tonini, L Cavichio, M Bazan, J Almeida, M Cavalcante, J Fukushima, S Vieira, E Osawa

Outcome of older patients with cancer requiring ICU admission

L Hajjar, M Franca Cavalcante, F Galas, JT Fukushima, MR Sundin, F Bergamin, C Park, H Palomba, DM Goto, A Tavares, M Santos, A Freitas, P Tonini, L Cavichio, JP Almeida, M Bazan

Identifying risk factors for readmission to the ICU: a qualitative approach

DG Strange, K Tjelle, A Lindhardt, K Jensen

Clinical and laboratory postoperative impact on outcome of living donor liver transplantation recipients

Y Nassar, K Omar, A Battah, A Mwafy

Are APACHE II scores better predictors of mortality than routine laboratory values?

Z Baykara, H Özocak, A Kuş, Z Arslan, B Yüksel, C Aksu, M Ertagin, M Solak, K Toker

Complementarity of prognosis models SAPS 3 and EuroSCORE in cardiac surgery

MJ Delgado-Amaya, E Curiel-Balsera, MD Arias-Verdu, E Castillo-Lorente, FJ Carrero-Gómez, E Aguayo-DeHoyos, A Herruzo-Avilés

Comparing intensive care treated primary, secondary and tertiary sepsis with respect to length of stay, organ failure and mortality: a pilot study

S Castegren, M Jonasson, J Sjölin, M Castegren

Survival of older patients after critical care

D Ashton-Cleary, R Sinclair

Eldicus scores for admission to our ICU: a retrospective study

G Zani, B Gemelli, S Vitali, C Villani, R Ragazzi, S Spadaro, CA Volta, R Alvisi

Developing a screening instrument for predicting psychological morbidity after critical illness

A Schandl, M Bottai, E Hellgren, Ö Sundin, P Sackey

Prediction of sequences of organ dysfunction in critical patients studied with Bayesian analysis

M Sandri, P Berchialla, D Gregori, L Gottin, V Sweiger, E Polati, RA De Blasi

Comparison of IGS 2 score and a new neural network biomarker score performance in predicting 1-year mortality

C Romdhani, I Labbene, M Belhadj Amor, Z Hajjej, A Massoudi, M Ferjani

Significance of preadmission quality of life for mortality in the ICU: a prospective cohort study

RB Bukan, A Moeller, M Henning, K Mortensen, T Klausen, T Waldau

Predicting physical function and mental health in trauma intensive care patients 2 years after hospitalisation

L Aitken, B Macfarlane, W Chaboyer, M Schuetz, C Joyce, AG Barnett

Do ICU patients' discharge characteristics change with Swiss Diagnosis Related Groups?

G Rauchenstein-Ziltener, CA Rüst, P Fodor, S Blumenthal

Do Diagnosis Related Groups change admission practice to a large Swiss ICU?

K Homburg, CA Rüst, P Fodor, S Blumenthal

Variable cost of a Greek ICU

E Tsigou, D Karabatsou, E Boutzouka, V Psallida, G Baltopoulos, M Tsironi

Audit of the medical staffing of and referrals to a mixed adult ICU in a teaching hospital

A Needham, T Lyndham, D O'Neil, J Greiff

Impact of the time elapsed between ICU request and actual admission on mortality and length of stay

GM Filho, TA Silva, AR Santana, FB Soares, LJ Almeida, LG Godoy, TA Rodrigues, MO Maia, JA Neto, AP Amorim, EB Moura, FF Amorim

Medical problems: review from the major nuclear incidents

Y Haraguchi, Y Tomoyasu, H Nishi, M Hoshino, M Sakai, E Hoshino

Variation in acute care burden and supply across diverse urban settings

S Murthy, S Austin, H Wunsch, NK Adhikari, V Karir, K Rowan, ST Jacob, J Salluh, F Bozza, B Du, Y An, B Lee, F Wu, C Oppong, R Venkataraman, V Velayutham, D Angus

Differences in severity and resource utilization for medical and surgical ICU patients

BH Nathanson, WT McGee, E Lederman, TL Higgins

Educational effectiveness of introductory training for the Rapid Response System in Japan

T Kodama, M Nakagawa, E Kawamoto, S Fujiwara, H Imai, S Fujitani, K Atagi

Standards of referrals and admissions of critically ill patients to the ICU

A Ng

Knowledge of confidentiality, consent and information disclosure is not affected by position or experience in adult critical care

M Lowings, A Molokhia, C Anderson, S Cowman, T Dixson, K El-Boghdadly, L Williams

Survey of alcohol-related admissions to critical care and the resource and financial implications

M Slattery, P Temblett, M Heatley, N Singatullina, B Jones

Association of sleep disordered breathing with clinical trajectories in patients undergoing cardiac surgery

J Roggenbach, B Tan, E Von der Leyen, A Weymann, M Karck, E Martin, S Hofer

Can massage therapy help cardiac patients? A literature review plus a case study

A Fenlon

Ischemic stroke in different ICU types

M Damasceno, F Rodriguez, R Turon

Prevention of ventilator-associated pneumonia in the surgical ICU at Siriraj Hospital

CH Pisitsak, O Chaiwat

Development of a severe influenza critical care curriculum and training materials for resource-limited settings

JV Diaz, P Lister, JR Ortiz, NK Adhikari, N Adhikari

Quality assurance in severe sepsis: an individualised audit/feedback system results in substantial improvements at a UK teaching hospital

M Simmonds, E Blyth, W Robson, M Chikhani

Safety climate perception for staff nurses in an ICU

RL Rivera-Romero, M Torres-Campos, MJ Delgado-Amaya, E Curiel-Balsera, JG Quesada-García

Physico-technical medicine: teaching technical skills to the intensivist

J Seifried, S Richter, J Guttmann, S Schumann

First-hour protocol clarifies resource management and nursing staff education in the ICU

M Arbelius-Iltanen, R Siren, J Heinilä, P Korhonen, T Sutinen, V Jalkanen, T Ahonen, S Karlsson

Influence of critical care nurse education and work environment on outcomes of mechanically ventilated older adults

DM Kelly, LH Aiken

Activity and case-mix changes in a medical ICU after the geographical transfer of a third-level university hospital

JC Cebrián, FM Monsalve, JB Bonastre

Are general wards sufficiently staffed to care for level 1 patients?

G Rajendran, C Tjen, S Hutchinson, S Fletcher

Sleep quality among ICU workers

G Burghi, I Serkochian, B Frache, P Alzugaray, K Goinheix, M Rodriguez Verde, H Bagnulo, E Azoulay

Work-related stress amongst doctors in intensive care, anaesthetics, accident and emergency and general medicine

JI Tuthill, MS Ahmed, G Mathew, AC Bolton, AA Molokhia

Audit of obstetric critical care admissions in a high-risk population

K El-Boghdadly, J Aron, DN Onwochei

Influence of adverse drug events on the mortality and the length of hospital stay in ICUs in Japan: the JADE Study

Y Ohta, M Sakuma, D Bates, T Morimoto

Attitude and knowledge of intensive care staff concerning donation in Hungary: it is the first step to change

A Smudla, S Mihály, J Fazakas

Specialist nurse for organ donation in an emergency department will increase organ donation

T Neill, J Millar, P O'Connor, P Glover

Sepsis in HIV patients admitted to the ICU

P Vidal-Cortés, P Lameiro-Flores, M Mourelo-Fariña, A Aller-Fernández, R Gómez-López, P Fernández-Ugidos, M Alves-Pérez, E Rodríguez-García

Mortality related to respiratory failure among pediatric hematology patients requiring intensive care

H Okuno, K Atagi, H Shimaoka

Survival of critically ill patients with haematological malignancies compared with patients without haematological malignancy

R Pugh, P Hampshire, P Hajimichael

Outcome of critically ill patients with haematological malignancy admitted to the ICU as an emergency

T Lofaro, S Easdale, S Rowe, M Ostermann, R Carr

Effect of organizational structure of the ICU on the prognosis: open format versus semi-closed format

T Taniguchi, M Okajima

Use of defaults on an electronic prescribing tool influences the type of fluid received by patients

L Herbert, C Bordeaux, M Thomas, L Burrows, J Bewley, T Gould

Automated, electronic monitoring for early detection of sepsis

S Rauch, M Fischer, C Martin, A Sablotzki

Admission to the ICU overnight: is it really a bad thing?

M Adams, P Dean, K MacDowall, P Stenhouse, A Mackay

Assessing the quality of interdisciplinary rounds

EC Ten Have, JE Tulleken

Leadership training and quality improvement of interdisciplinary rounds in the ICU

EC Ten Have, JE Tulleken

Let's go round again! Quality improvement through intentional rounding

P Doyle, F Cox, R Tollyfield, A Seraj

Prospective observational study of handover in a medical ICU

A Mukhopadhyay, B Leong, A Lua, R Aroos, J Wong, N Koh, N Goh, K See, J Phua, Y Kowitlawakul

Impact of knowledge transfer through the implementation of a telemedicine program in a community hospital in Brazil

CA Abreu Filho, M Steinman, A Andrade, R Cal, N Akamine, J Teixeira, E Silva, A Kanamura, M Cenderoglo, C Lottenberg

Utilization of telemedicine to improve burn care in a developing country

J Knittel, G Fuzaylov

Different aspects of therapy limitation: a comparative study of the nurse's view

O Szücs, G Élö, L Szabó, C Varga, J Gál, L Zubek

Alternative to improve palliative care for all patients and families in critical care units: development and preliminary evaluation following MRC guidance of the King's Psychosocial, Assessment and Care tool

I Higginson, C Rumble, J Koffman, P Hopkins, S Heenen, W Prentice, R Burman, S Leonard, O Dampier, J Noble, M Morgan, C Shipman

End-of life thoughts in the ICU: results of a survey

A Yaguchi, M Namiki, N Saito, R Nagai, M Takeda, T Harada, R Moroi

End-of-life decisions in Slovenian ICUs: a cross-sectional survey

S Grosek, M Orazem, M Kanic, G Vidmar, U Groselj

Attitudes of intensivists in the UK to withdrawal of futile therapy

M Mariyaselvam, M Irvine, J Carter, M Blunt, P Young

Parent's perception on end-of-life care in Brazil

P Lago, J Piva, G Halal, M Halal

Getting critical care patients home for end-of-life care

LS Nielsen

Project PIX (Post Intensive care eXercise): impact on physical fitness and focus group analysis of quality of life following exercise rehabilitation

J Goodman, W Walker, J Wright, G Danjoux, S Howell, D Martin, S Bonner

Feasibility of neuromuscular electrical stimulation in critically ill patients

J Segers, G Hermans, F Bruyninckx, G Meyfroidt, D Langer, R Gosselink

Follow-up and counseling service in trauma patients: needs and goals - a preliminary study

DL Grieco, M Biancone, SL Cutuli, G Pintaudi, MT Santantonio, ES Tanzarella, F Toni, AG De Belvis, MG Bocci, C Sandroni, M Antonelli

Post-traumatic stress disorder - are we doing all we can? A UK national-based survey

X Watson

Implementation of an ICU follow-up clinic: outcomes and patient satisfaction after 1 year

G De la Cerda

Acute exercise response in the critically ill

N Collings, R Young

Randomized, controlled pilot study of early rehabilitation strategies in acute respiratory failure

D Files, P Morris, S Shrestha, S Dhar, M Young, J Hauser, E Chmelo, C Thompson, L Dixon, K Murphy, B Nicklas, M Berry

Early results of a 6-week exercise programme in post-ICU patients

C Battle, K James, P Temblett, H Hutchings

Recognition of the primary stressors affecting intensive care patients: a systematic review

S Birch, S Elliot

Quality of care in the ICU from the perspective of relatives

M Van Mol, E Bakker, A Rensen, I Menheere, L Verharen

Family satisfaction in the ICU: enhancing patient experience

E Kursumovic, J Bilinska, A Molokhia

Family satisfaction with patient care in ICUs of nonacademic Brazilian public hospitals

J Othero, AB Cavalcanti, JC Mouro, K Normilio-da-Silva, R Pusch, F Moreira, AA Kodama, O Berwanger

Prognostic scores and infective endocarditis

P Fernandez Ugidos, R Gomez Lopez, P Vidal Cortes, A Ceniceros Barros, L Seoane Quiroga, JM Lopez Perez

Effectiveness of early ureteric stenting for urosepsis associated with urinary tract calculi

S Nishiguchi, Y Tokuda

Implementation of a sepsis protocol in a community hospital using a Telemedicine Program

M Steinman, CA Abreu Filho, A Andrade, R Cal, N Akamine, J Teixeira, E Silva, A Kanamura, M Cenderoglo, C Lottenberg

Initial Brazilian experience of Telestroke for thrombolysis in a community hospital

CA Abreu Filho, A Caluza, M Steinman, G Silva, R Cal, N Akamine, J Teixeira, A Andrade, E Silva, A Kanamura, M Cenderoglo, C Lottenberg

Analysis of emergency calls achieved in a French emergency dispatching centre: what resources for which patients

O Tilak, J Cuny, N Assez, P Goldstein, E Wiel

Reform of emergency services: immediate effects on cardiac care unit and ICU patient intake

AO Alaspää, T Valpas, V Rautava, A Palomäki

Overtriage and undertriage in a prehospital system over 7 years

L Carenzo, F Barra, A Messina, D Colombo, T Fontana, F Della Corte

Lorca's hospital evacuation and medical attention by the emergency department

L Escobar Alvaro, J Jimenez Gonzalez, A Pelaez Ballesta, A Corbatón Anchuelo

War injuries and civilian accidents in Afghan children

R Kedzierewicz, P Ramiara, M Puidupin, S Mérat

Intensive care and disaster medicine: the role of a compendium

Y Haraguchi, Y Tomoyasu, H Nishi, M Hoshino, T Tsubata, M Sakai, E Hoshino

Algorithm for the resuscitation of traumatic cardiac arrest patients in a physician-staffed helicopter emergency medical service

PB Sherren, C Reid, K Habig, B Burns

Are physicians required during HEMS winch rescue missions?

PB Sherren, C Hayes-Bradley, C Reid, B Burns, K Habig

Improving maintenance of critical care land and aeromedical transfer equipment

D Ashton-Cleary, N Boyd

Innate immune response-mediated late increase in SuPAR in multi-trauma patients

K Timmermans, M Kox, M Vaneker, P Pickkers

Accuracy of FAST scan in blunt abdominal trauma in a major London trauma centre

S Fleming, R Bird, K Ratnasingham, S Sarker, M Walsh, B Patel

Cognitive performance and capacity to return home following out-of-hospital cardiac arrest

J Petrie, C Lockie, S Brett, R Stümpfle

Start value of cerebral saturation in prehospital cardiac arrest patients: does it mean something?

C Genbrugge, I Meex, S Scheyltjens, J Dens, C De Deyne

Intensive care admission after cardiac arrest: cardiac versus noncardiac causes and consequences for treatment

T Hargreaves, H Kingston, M Crews, M Mogk, I Welters

Comparison of 1-year neurological outcome between intra-hospital and extra-hospital cardiac arrest survivors submitted to mild therapeutic hypothermia in a community-based setting in Brazil

CA Abreu Filho, A Andrade, A Neto, S Santos, M Bracco, E Silva, A Baruzzi, J Teixeira

Primary percutaneous coronary angioplasty and therapeutic hypothermia in out-of-hospital cardiac arrest

R Hunt, M Holl, A Bailey, P Macnaughton

Effects of viscosity on cerebral blood flow after cardiac arrest

L Bisschops, G Pop, S Teerenstra, J Van der Hoeven, C Hoedemaekers

Therapeutic mild hypothermia after cardiac arrest in shockable and nonshockable rhythms: does it improve both survival and neurological outcome?

A Gupta

Agreement between temperature measurements during cooling and warming through the esophagus

EB Kulstad, DM Courtney, P Shanley, A Metzger, T Matsuura, J Rees, K Lurie, S McKnite

Association between oxygenation and 6-month mortality during post-cardiac arrest care

M Skrifvars, J Vaahersalo, M Reinikainen, S Bendel, J Kurola, M Tiainen, R Raj, V Pettilä, T Varpula, FinnResusci Study Group

Neuron-specific enolase and bispectral index/suppression ratio for prognostication after cardiac arrest

M Van Laer, K Deschilder, P Lormans, J Gillet, W Stockman

Motor scores, therapeutic hypothermia and neurological outcome after cardiac arrest

M Davidson

Differences of calcium binding protein immunoreactivities in the young hippocampal CA1 region from the adult following transient ischemic damage

CW Park, HY Lee, JH Cho, MH Won

Early hypothermia improves survival and reduces the rise of serum biomarkers after traumatic brain injury in swine

M Kumar, AD Goldberg, M Kashiouris, L Keenan, A Rabinstein

Epidemiology of moderate and severe traumatic brain injury in Cairo University Hospital in 2010

T Montaser, A Hassan

Alcohol intoxication impedes the recognition of traumatic brain injury in the prehospital setting and may worsen 6-month outcome

R Raj, J Siironen, R Kivisaari, M Kuisma, M Skrifvars

Renal resistive index can predict response to furosemide in septic patients with oliguria

I Gornik, A Godan, V Gasparovic

Effect of probiotic containing lactobacillus, bifidobacterium and streptococcus thermophilus in critically ill patients

M Ebrahimi Mamaghani, S Sanaie, A Mahmoudpour, H Hamishehkar

Erratum to: Urinary neutrophil gelatinase-associated lipocalin as an early predictor of acute kidney injury in cardiac surgery patients

T García, AJ Betbesé, M García, M Argilaga, A Castellví, J Ordonez-Llanos

Erratum to: The use, type and duration of cardiopulmonary bypass are related to acute kidney injury occurrence and urinary NGAL concentrations

T García, AJ Betbesé, M García, V Baños, R Bonet, J Ordonez-Llanos

Erratum to: Current practices in ICU delirium management: a prospective multicenter study in the Netherlands

Z Trogrlic, E Ista, A Slooter, H Ponssen, J Schoonderbeek, F Schreiner, S Verbrugge, S Duran, J Bakker, M van der Jagt

Erratum to: Current perspectives, beliefs and practices concerning delirium in critically ill patients: a multicenter survey among Dutch healthcare professionals

Z Trogrlic, M van der Jagt, P van der Voort, H Ponssen, J Schoonderbeek, F Schreiner, S Verbrugge, S Duran, J Bakker, E Ista