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BMC Infectious Diseases
Published in: BMC Infectious Diseases 1/2022

Open Access 01-12-2022 | COVID-19 | Correspondence

Issues with reporting and interpretation of Khan et al. 2021

Authors: Nicholas J. DeVito, Henry Drysdale

Published in: BMC Infectious Diseases | Issue 1/2022

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Abstract

A recent publication in BMC Infectious Diseases concerning the use of convalescent plasma for the treatment of COVID-19 had a number of major issues. This correspondence details specific instances of unclear reporting as well as major omissions when discussing the context of the trial. These render the study's findings and conclusions misleading.
Literature
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Khan TNS, Mukry SN, Masood S, Meraj L, Devrajani BR, Akram J, et al. Usefulness of convalescent plasma transfusion for the treatment of severely ill COVID-19 patients in Pakistan. BMC Infect Dis. 2021;21:1014.CrossRef
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Moher D, Hopewell S, Schulz KF, Montori V, Gøtzsche PC, Devereaux PJ, et al. CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. BMJ. 2010;340: c869.CrossRef
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Liu STH, Lin H-M, Baine I, Wajnberg A, Gumprecht JP, Rahman F, et al. Convalescent plasma treatment of severe COVID-19: a propensity score-matched control study. Nat Med. 2020;26:1708–13.CrossRef
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Janiaud P, Axfors C, Schmitt AM, Gloy V, Ebrahimi F, Hepprich M, et al. Association of convalescent plasma treatment with clinical outcomes in patients with COVID-19: a systematic review and meta-analysis. JAMA. 2021;325:1185–95.CrossRef
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Abani O, Abbas A, Abbas F, Abbas M, Abbasi S, Abbass H, et al. Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial. Lancet. 2021;397:2049–59.CrossRef
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Gøtzsche PC. Citation bias: questionable research practice or scientific misconduct? J R Soc Med. 2022;115:31–5.CrossRef
Metadata
Title
Issues with reporting and interpretation of Khan et al. 2021
Authors
Nicholas J. DeVito
Henry Drysdale
Publication date
01-12-2022
Publisher
BioMed Central
Keyword
COVID-19
Published in
BMC Infectious Diseases / Issue 1/2022
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-022-07551-8

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