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Published in: BMC Neurology 1/2022

Open Access 01-12-2022 | COVID-19 Vaccination | Case report

Acute dizziness and mental alteration associated with Moderna COVID-19 vaccine: a case report

Authors: Rizaldy Taslim Pinzon, Fillia Kristyawati Haryono, Nikolaus Erik Darmawan, Mia Amelia Mutiara Salikim, Vanessa Veronica

Published in: BMC Neurology | Issue 1/2022

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Abstract

Background

Due to a rising number of COVID-19 cases, the Indonesian government implemented public health programs to lower the rate. Since January 2021, one of the government’s primary policies has been the COVID-19 immunization program. Recently, the Moderna messenger ribonucleic acid (mRNA) vaccine is one of the COVID-19 vaccines used in Indonesia. Based on some research, Moderna has possible side effects throughout the body, including neurological symptoms.

Case presentation

We describe a 39-year-old female with uncontrolled hypertension who showed behavioral change, communication difficulty, social withdrawal, and a confused state within 7 days from getting her first dose of the Moderna vaccine. The patient had a history of febrile convulsion in childhood. An increase of neutrophil-to-lymphocyte ratio (16.9) and C-reactive protein level (31.75 mg/L) indicates ongoing inflammation. Head CT scan shows no abnormalities. She received ceftriaxone, citicoline, and methylprednisolone. The patient was discharged on the seventh day and completely recovered 1 week later. This study is the first case report of encephalopathy following the administration of the Moderna COVID-19 vaccine reported in Indonesia up to our knowledge.

Conclusion

Encephalopathy related to the Moderna COVID-19 vaccine should be acknowledged as an adverse effect of the Moderna COVID-19 vaccine.
Literature
Metadata
Title
Acute dizziness and mental alteration associated with Moderna COVID-19 vaccine: a case report
Authors
Rizaldy Taslim Pinzon
Fillia Kristyawati Haryono
Nikolaus Erik Darmawan
Mia Amelia Mutiara Salikim
Vanessa Veronica
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2022
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-022-02834-8

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