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01-04-2019 | Coronavirus | Annotated Sequence Record

Molecular characteristics of a novel recombinant of porcine epidemic diarrhea virus

Authors: Mariia Nefedeva, Ilya Titov, Alexander Malogolovkin

Published in: Archives of Virology | Issue 4/2019

Abstract

Porcine epidemic diarrhea (PED) is a contagious viral disease in pigs, caused by the coronavirus porcine epidemic diarrhea virus (PEDV). PEDV infection results in significant mortality in piglets in unvaccinated herds. Like many others RNA viruses, PEDV has high evolutionary rate and is prone to genetic mutations. In this study, we analyzed the complete genome sequence of the recently sequenced isolate PEDV/Belgorod/dom/2008. A recombination event in S gene of PEDV/Belgorod/dom/2008 was detected. Pairwise identity analysis of the whole genome sequences revealed that PEDV/Belgorod/dom/2008 is an intermediate between PEDV and transmissible gastroenteritis virus (TGEV) strains. These results can be used for further analysis of the evolutionary variability, prevalence, and epidemiology of the porcine epidemic diarrhea virus.

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Title: Molecular characteristics of a novel recombinant of porcine epidemic diarrhea virus
Authors: Mariia Nefedeva
Ilya Titov
Alexander Malogolovkin
Publication date: 01-04-2019
Publisher: Springer Vienna
Keywords: Coronavirus
Diarrhea
Diarrhea
Published in: Archives of Virology / Issue 4/2019
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-019-04166-4

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