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Obstructive Lung Diseases Chronic Obstructive Lung Disease

Chronic Obstructive Lung Disease

Support for high-flow nasal oxygen from RENOVATE trial

High-flow nasal oxygen is noninferior to noninvasive ventilation for preventing endotracheal intubation and death in patients with different causes of acute respiratory failure.

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Editor's Choice

Tezepelumab fails to reduce severe COPD exacerbations

Treatment with the monoclonal antibody tezepelumab does not significantly reduce the annualized rate of moderate or severe chronic obstructive pulmonary disease exacerbations.

Benralizumab best for treating acute eosinophilic exacerbations

Benralizumab significantly reduces treatment failure rates and improves symptoms of eosinophilic exacerbations versus prednisolone in people with asthma or chronic obstructive pulmonary disease.

Do antidepressants worsen COPD outcomes?

Depression in patients with COPD is associated with poorer outcomes. But recent studies have also brought into question the safety of antidepressants in this setting. How can you balance the risks and benefits for your patients?

Social isolation linked to higher mortality in COPD patients

Social isolation shows a significant association with increased mortality in adults with chronic obstructive pulmonary disease.

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SPONSORED

Targeting COPD with type 2 inflammation: emerging biologic landscape

  • Webinar | 03-12-2024 | 19:00 (CET)

Join us for an insightful session tailored for pulmonologists and healthcaree professionals eager to enhance their understanding of COPD and the latest advances in biologic therapies. 

On-demand version coming soon

Sponsored by:
  • Sanofi
Developed by: Springer Healthcare
Learn more

Case Studies

Superior vena cava syndrome induced by COPD

Superior vena cava (SVC) syndrome occurs when the SVC is either partially or completely obstructed. In this case of an elderly patient with dyspnea, a thoracic CT showed SVC caused by lung hyperinflation due to chronic obstructive pulmonary disease. 

Current Reviews

Diaphragmatic ultrasound: approach, emerging evidence, and future perspectives in non-ICU patients

Diaphragmatic dysfunction is an important contributor to hypercapnic respiratory failure, but its presence is often challenging to determine at the bedside. Diaphragm ultrasound provides an opportunity to evaluate the function of the diaphragm …

Εosinophilic Chronic Obstructive Pulmonary Disease. What Do We Know So Far?

The latest advances in asthma treatment have highlighted the significance of eosinophilia and the possible role of some pro-eosinophilic mediators, like interleukins (IL) IL-5, IL-4/IL-13, and IL-33 in the disease’s pathogenesis. Considering that …

Risk factors for conversion from minimally invasive surgery to thoracotomy in patients with lung cancer: outcomes from a pooled analysis

The purpose of this study is to explore the risk factors for conversion from minimally invasive surgery to thoracotomy in patients with lung cancer through meta-analytic approach, and provide a better evidence-based basis for clinicians to perform …

Progress of CCL20-CCR6 in the airways: a promising new therapeutic target

The chemokine CCL20, a small cytokine that belongs to the C–C chemokine family, interacts with its homologous receptor CCR6, which is expressed on wide range of cell types. According to current research, the CCL20-CCR6 has been established as …

CME & eLearning

SPONSORED

Webinar

1.5 European CME credits (ECMEC®s)

Enhance your understanding of COPD with type 2 inflammation and learn about the evolving treatment landscape, in this webinar tailored for pulmonologists and healthcare professionals with an interest in respiratory medicine.

Sponsored by:
  • Sanofi
Developed by: Springer Healthcare

Infographic

This expert-led infographic explains how to recognize and manage COPD exacerbations and explores the impact of these exacerbations at the patient and physician level.

Supported by:
  • Sanofi and Regeneron
Developed by: Springer Healthcare

Further Reading

Barriers and enablers to medicine-taking behaviours in chronic obstructive pulmonary disease: a qualitative interview study

People with COPD have unmet needs regarding provided care and their medicines which future interventions need to consider and account for in intervention design processes Mapping medicine-taking barriers and enablers to the theoretical domains …

The relationship between fatigue levels and psychosocial adjustment in elderly individuals with chronic obstructive pulmonary disease: A descriptive study

  • Open Access
  • Fatigue
  • Original Article

With increasing life expectancy and an aging population, the number of people affected by chronic diseases is rising. Chronic diseases are characterized by their slow impact on an individual’s health, long-term nature, recurrence, and …

Retrospective Cohort Study of Elderly Users of Single- or Multiple-Inhaler Triple Therapy for the Treatment of Asthma in the USA

Asthma places a major clinical and economic burden in the USA. It affects approximately 25 million people [ 1 ] and is a leading cause of mortality [ 2 ], and between 2008 and 2013 it accounted for $50 billion in medical costs and $32 billion in …

Identification and Construction of a R-loop Mediated Diagnostic Model and Associated Immune Microenvironment of COPD through Machine Learning and Single-Cell Transcriptomics

Chronic obstructive pulmonary disease (COPD) is a prevalent chronic inflammatory airway disease with high incidence and significant disease burden. R-loops, functional chromatin structure formed during transcription, are closely associated with …