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Published in: Journal of Orthopaedic Science 2/2013

01-03-2013 | Original Article

Contamination of surfaces for osseointegration of cementless total hip implants by small aluminium oxide particles: analysis of established implants by use of a new technique

Authors: Alexander Kolb, Georg Reinisch, Manuel Sabeti-Aschraf, Alexander Grübl, Reinhard Windhager

Published in: Journal of Orthopaedic Science | Issue 2/2013

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Abstract

Background

The failure of total hip replacements because of wear, particle-induced osteolysis, and aseptic loosening has focussed interest on factors potentially affecting the rate of wear. In this context the effect of particle release from the bone–implant interface of cementless implants is poorly understood. The surface structure for bony ongrowth of many cementless implants is created by grit-blasting. Remnants from this process (Al2O3 particles) on these surfaces have been reported; these remnants have the potential to cause third-body wear.

Methods

We report a novel technique for isolation and quantification of alumina particle contamination. Stems from different manufacturers were electrochemically activated and etched to isolate the alumina residues. After filtration the particles were characterised by scanning electron microscopy and energy-dispersive X-ray analysis.

Results

Many Al2O3 particles were found on all the implants tested. A mean of 426,814 particles per mm2 was measured. Particle size distribution ranged from 0.125 to 66.304 μm with a peak in the range 0.25–1 μm.

Conclusions

Our main finding was a large amount of small Al2O3 particles on all blasted surfaces. On the basis of our results these alumina particle remnants cannot be excluded as a factor causing increased third-body wear.
Literature
1.
go back to reference Morscher EW. European experience with cementless total hip replacements. Hip. 1983, 190–203. Morscher EW. European experience with cementless total hip replacements. Hip. 1983, 190–203.
2.
go back to reference Zweymuller K, Semlitsch M. Concept and material properties of a cementless hip prosthesis system with Al2O3 ceramic ball heads and wrought Ti-6Al-4V stems. Arch Orthop Trauma Surg. 1982;10:229–36.CrossRef Zweymuller K, Semlitsch M. Concept and material properties of a cementless hip prosthesis system with Al2O3 ceramic ball heads and wrought Ti-6Al-4V stems. Arch Orthop Trauma Surg. 1982;10:229–36.CrossRef
3.
go back to reference Zweymuller K, Lintner FK, Semlitsch MF. Biologic fixation of a press-fit titanium hip joint endoprosthesis. Clin Orthop. 1988;235:195–206.PubMed Zweymuller K, Lintner FK, Semlitsch MF. Biologic fixation of a press-fit titanium hip joint endoprosthesis. Clin Orthop. 1988;235:195–206.PubMed
4.
go back to reference Kolb A, Grübl A, Schneckener CD, Chiari C, Kaider A, Lass R, Windhager R. Cementless total hip arthroplasty with the rectangular titanium Zweymüller stem: a concise follow-up, at a minimum of twenty years, of previous reports. J Bone Joint Surg Am. 2012;94(18):1681–4.PubMedCrossRef Kolb A, Grübl A, Schneckener CD, Chiari C, Kaider A, Lass R, Windhager R. Cementless total hip arthroplasty with the rectangular titanium Zweymüller stem: a concise follow-up, at a minimum of twenty years, of previous reports. J Bone Joint Surg Am. 2012;94(18):1681–4.PubMedCrossRef
5.
go back to reference Grübl A, Kolb A, Reinisch G, Fafilek G, Skrbensky G, Kotz R. Characterisation, quantification, and isolation of aluminium oxide particles on grit blasted titanium aluminium alloy hip implants. J Biomed Mater Res B Appl Biomater. 2007;83:127–31.PubMed Grübl A, Kolb A, Reinisch G, Fafilek G, Skrbensky G, Kotz R. Characterisation, quantification, and isolation of aluminium oxide particles on grit blasted titanium aluminium alloy hip implants. J Biomed Mater Res B Appl Biomater. 2007;83:127–31.PubMed
6.
go back to reference Schuh A, Uter W, Kachler W, Goske J, Zeiler G, Lill C. Comparative surface examinations on corund blasted titanium implants and explants in total hip arthroplasty. Arch Orthop Trauma Surg. 2005;125:676–82.PubMedCrossRef Schuh A, Uter W, Kachler W, Goske J, Zeiler G, Lill C. Comparative surface examinations on corund blasted titanium implants and explants in total hip arthroplasty. Arch Orthop Trauma Surg. 2005;125:676–82.PubMedCrossRef
7.
go back to reference Böhm G, Lintner F, Auterith A, Lester DK, Zweymüller KA. Morphometric examination of straight, tapered titanium stems: a retrieval study. Clin Orthop Relat Res. 2001;393:13–24.PubMedCrossRef Böhm G, Lintner F, Auterith A, Lester DK, Zweymüller KA. Morphometric examination of straight, tapered titanium stems: a retrieval study. Clin Orthop Relat Res. 2001;393:13–24.PubMedCrossRef
8.
go back to reference Schmalzried TP, Jasty M, Harris WH. Periprosthetic bone loss in total hip arthroplasty. J Bone Joint Surg Am. 1992;74:849–63.PubMed Schmalzried TP, Jasty M, Harris WH. Periprosthetic bone loss in total hip arthroplasty. J Bone Joint Surg Am. 1992;74:849–63.PubMed
9.
go back to reference Böhler M, Kanz F, Schwarz B, Steffan I, Walter A, Plenk J Jr, Knahr K. Adverse tissue reactions to wear particles from co-alloy articulations, increased by aluminium-blasting particle contamination from cementless Ti-based total hip implants. J Bone Joint Surg Br. 2002;84:128–36.PubMedCrossRef Böhler M, Kanz F, Schwarz B, Steffan I, Walter A, Plenk J Jr, Knahr K. Adverse tissue reactions to wear particles from co-alloy articulations, increased by aluminium-blasting particle contamination from cementless Ti-based total hip implants. J Bone Joint Surg Br. 2002;84:128–36.PubMedCrossRef
10.
go back to reference Reinisch G, Judmann K, Lhotka C, Lintner F, Zweymüller K. Retrieval study of uncemented metal–metal hip prostheses revised for early loosing. Biomaterials. 2003;24:1081–91.PubMedCrossRef Reinisch G, Judmann K, Lhotka C, Lintner F, Zweymüller K. Retrieval study of uncemented metal–metal hip prostheses revised for early loosing. Biomaterials. 2003;24:1081–91.PubMedCrossRef
11.
go back to reference Raimondi MT, Vena P, Pietrabissa R. Quantitative evaluation of the prosthetic head damage induced by microscopic third-body particles in total hip replacement. J Biomed Mater Res. 2001;58:436–48.PubMedCrossRef Raimondi MT, Vena P, Pietrabissa R. Quantitative evaluation of the prosthetic head damage induced by microscopic third-body particles in total hip replacement. J Biomed Mater Res. 2001;58:436–48.PubMedCrossRef
12.
go back to reference Elfick AP, Green SM, Krikler S, Unsworth A. The nature and dissemination of UHMWPE wear debris retrieved from periprosthetic tissue of THR. J Biomed Mater Res A. 2003;65:95–108.PubMedCrossRef Elfick AP, Green SM, Krikler S, Unsworth A. The nature and dissemination of UHMWPE wear debris retrieved from periprosthetic tissue of THR. J Biomed Mater Res A. 2003;65:95–108.PubMedCrossRef
13.
go back to reference Canabarro A, Diniz MG, Paciornik S, Carvalho L, Sampaio EM, Beloti MM, Rosa AL, Fischer RG. High concentration of residual aluminium oxide on titanium surface inhibits extracellular matrix mineralization. J Biomed Mater Res A. 2008;87:588–97.PubMed Canabarro A, Diniz MG, Paciornik S, Carvalho L, Sampaio EM, Beloti MM, Rosa AL, Fischer RG. High concentration of residual aluminium oxide on titanium surface inhibits extracellular matrix mineralization. J Biomed Mater Res A. 2008;87:588–97.PubMed
14.
go back to reference Rodrigo A, Vallés G, Saldaña L, Rodríguez M, Martínez ME, Munuera L, Vilaboa N. Aluminium particles influence the interactions of cocultured osteoblasts and macrophages. J Orthop Res. 2006;24:46–54.PubMedCrossRef Rodrigo A, Vallés G, Saldaña L, Rodríguez M, Martínez ME, Munuera L, Vilaboa N. Aluminium particles influence the interactions of cocultured osteoblasts and macrophages. J Orthop Res. 2006;24:46–54.PubMedCrossRef
15.
go back to reference Walter WL, Clabeaux J, Wright TM, Walsh W, Walter Wk, Sculco TP. Mechanisms for pumping fluid through cementless acetabular components with holes. J Arthroplasty. 2005;20:1042–8.PubMedCrossRef Walter WL, Clabeaux J, Wright TM, Walsh W, Walter Wk, Sculco TP. Mechanisms for pumping fluid through cementless acetabular components with holes. J Arthroplasty. 2005;20:1042–8.PubMedCrossRef
Metadata
Title
Contamination of surfaces for osseointegration of cementless total hip implants by small aluminium oxide particles: analysis of established implants by use of a new technique
Authors
Alexander Kolb
Georg Reinisch
Manuel Sabeti-Aschraf
Alexander Grübl
Reinhard Windhager
Publication date
01-03-2013
Publisher
Springer Japan
Published in
Journal of Orthopaedic Science / Issue 2/2013
Print ISSN: 0949-2658
Electronic ISSN: 1436-2023
DOI
https://doi.org/10.1007/s00776-012-0343-4

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