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Open Access 01-10-2019 | Original Contribution

Consumption of dairy products in relation to the presence of clinical knee osteoarthritis: The Maastricht Study

Authors: Karlijn F. M. Denissen, Annelies Boonen, Johannes T. H. Nielen, Anouk L. Feitsma, Ellen G. H. M. van den Heuvel, Pieter J. Emans, Coen D. A. Stehouwer, Simone J. S. Sep, Martien C. J. M. van Dongen, Pieter C. Dagnelie, Simone J. P. M. Eussen

Published in: European Journal of Nutrition | Issue 7/2019

Abstract

Purpose

Observational studies showed inverse associations between milk consumption and knee osteoarthritis (knee OA). There is lack of information on the role of specific dairy product categories. We explored the association between dairy consumption and the presence of knee osteoarthritis in 3010 individuals aged 40–75 years participating in The Maastricht Study.

Methods

The presence of knee OA was defined according to a slightly modified version of the American College of Rheumatology (ACR) clinical classification criteria. Data on dairy consumption were appraised by a 253-item FFQ covering 47 dairy products with categorization on fat content, fermentation or dairy type. Multivariable logistic regression analyses were performed to estimate odd ratios (ORs) and 95% confidence intervals (95%CI), while correcting for relevant factors.

Results

427 (14%) participants were classified as having knee OA. Significant inverse associations were observed between the presence of knee OA and intake of full-fat dairy and Dutch, primarily semi-hard, cheese, with OR for the highest compared to the lowest tertile of intake of 0.68 (95%CI 0.50–0.92) for full-fat dairy, and 0.75 (95%CI 0.56–0.99) for Dutch cheese. No significant associations were found for other dairy product categories.

Conclusion

In this Dutch population, higher intake of full-fat dairy and Dutch cheese, but not milk, was cross-sectionally associated with the lower presence of knee OA. Prospective studies need to assess the relationship between dairy consumption, and in particular semi-hard cheeses, with incident knee OA.

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Title: Consumption of dairy products in relation to the presence of clinical knee osteoarthritis: The Maastricht Study
Authors: Karlijn F. M. Denissen
Annelies Boonen
Johannes T. H. Nielen
Anouk L. Feitsma
Ellen G. H. M. van den Heuvel
Pieter J. Emans
Coen D. A. Stehouwer
Simone J. S. Sep
Martien C. J. M. van Dongen
Pieter C. Dagnelie
Simone J. P. M. Eussen
Publication date: 01-10-2019
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Nutrition / Issue 7/2019
Print ISSN: 1436-6207
Electronic ISSN: 1436-6215
DOI: https://doi.org/10.1007/s00394-018-1818-7

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