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Published in: Digestive Diseases and Sciences 5/2009

01-05-2009 | CASE REPORT

Conjugated Linoleic Acid-Induced Toxic Hepatitis: First Case Report

Authors: Rui Ramos, Joana Mascarenhas, Patrícia Duarte, Célia Vicente, Carlos Casteleiro

Published in: Digestive Diseases and Sciences | Issue 5/2009

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Abstract

A 46-year-old female patient was referred to our department with presenting symptoms of asthenia, jaundice, and pruritus. There was no medical history or clinical evidence of viral hepatitis, autoimmune hepatitis, hemochromatosis, or Wilson’s disease. The patient revealed that 14 days prior to admission she had begun self-medicating with conjugated linoleic acid (CLA) to reduce body fat, leading to the suspicion of CLA hepatotoxicity, which was subsequently confirmed by a liver biopsy. After the patient ceased to ingest CLA, liver enzymes levels normalized. To the best of our knowledge, this is the first report of hepatotoxicity due to CLA ingestion.
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Metadata
Title
Conjugated Linoleic Acid-Induced Toxic Hepatitis: First Case Report
Authors
Rui Ramos
Joana Mascarenhas
Patrícia Duarte
Célia Vicente
Carlos Casteleiro
Publication date
01-05-2009
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 5/2009
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-008-0461-1

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