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01-10-2019 | Concise Commentary

Concise Commentary: Significance of Rapid Gastric Emptying in Dyspepsia—Is the Stomach 30% Empty or 30% Full?

Authors: Aashesh N. Verma, Ali Rezaie

Published in: Digestive Diseases and Sciences | Issue 10/2019

Excerpt

Rapid gastric emptying (RGE), defined as < 30% retention at the one hour mark of a gastric emptying study (GES), has classically been associated with conditions such as dumping syndrome or seen after surgery for peptic ulcer disease [1]. While RGE is an accepted entity, its clinical significance has been questioned, since gastric emptying and symptoms are poorly correlated [2], although more recent studies have suggested that in some patients, functional dyspepsia symptoms correlate with RGE [3]. …

Abell TL, Camilleri M, Donohoe K, et al. Consensus recommendations for gastric emptying scintigraphy: a joint report of the American Neurogastroenterology and Motility Society and the Society of Nuclear Medicine. Am J Gastroenterol. 2008;103:753–763.CrossRef

Balan K, Sonoda LI, Seshadri N, Solanki C, Middleton S. Clinical significance of scintigraphic rapid gastric emptying. Nucl Med Commun. 2011;32:1185–1189.CrossRefPubMed

Kusano M, Zai H, Shimoyama Y, et al. Rapid gastric emptying, rather than delayed gastric emptying, might provoke functional dyspepsia. J Gastroenterol Hepatol. 2011;26:75–78.CrossRefPubMed

Cifuentes J, Radetic M, Lopez R, Gabbard S. Clinical predictors of rapid gastric emptying in patients presenting with dyspeptic symptoms. Dig Dis Sci. (Epub ahead of print). https://doi.org/10.1007/s10620-019-05620-8.

Tack J, Janssen P, Masaoka T, Farré R, Van Oudenhove L. Efficacy of buspirone, a fundus relaxing drug, in patients with functional dyspepsia. Clin Gastroenterol Hepatol. 2012;10:1239–1245.CrossRefPubMed

Title: Concise Commentary: Significance of Rapid Gastric Emptying in Dyspepsia—Is the Stomach 30% Empty or 30% Full?
Authors: Aashesh N. Verma
Ali Rezaie
Publication date: 01-10-2019
Publisher: Springer US
Published in: Digestive Diseases and Sciences / Issue 10/2019
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI: https://doi.org/10.1007/s10620-019-05789-y

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