Skip to main content
Top
Published in: Abdominal Radiology 1/2009

01-01-2009

Computerized tomography virtual endoscopy in evaluation of upper urinary tract tumors: initial experience

Authors: Giuseppe Battista, Claudia Sassi, Riccardo Schiavina, Alessandro Franceschelli, Emanuela Baglivo, Giuseppe Martorana, Romeo Canini

Published in: Abdominal Radiology | Issue 1/2009

Login to get access

Abstract

Purpose

To assess the usefulness of CT virtual endoscopy (VE) as an integration of CT-urography, for the detection of upper urinary tract tumor in patients with hematuria.

Materials and methods

Fourteen patients with hematuria and high risk of transitional cell carcinoma of the upper urinary tract underwent urinary cytology, ultrasonography, excretory urography, cystoscopy, CT-urography with VE, and optical ureteroscopy. The CT urograms and VE were correlated with the pathological findings of surgical specimen (6/14) and cytological examination of ureteroscopy biopsy (8/14).

Results

VE revealed three renal pelvic and one ureteral tumors, not producing further information did not detected at CT-urography. In two patients VE showed findings strongly indicative of malignancies, not noticed at CT-urography: ureteroscopic biopsy revealed an advanced dysplastic lesion and a malignancy, confirmed at surgery. In one patient VE was questionable (narrowing of the distal ureter) and ureteroscopic biopsy revealed an inflammation. Finally, VE diagnosed a fibrosis of the lumbar ureteral tract, confirmed at ureteroscopic biopsy. In other six patients, VE and ureteroscopy did not find abnormalities.

Conclusion

VE should be useful as an integration of CT-urography for a complete evaluation of the upper urinary tract in patients with suspected tumor, limiting the need for fiberoptic ureteroscopic examination.
Literature
1.
go back to reference Wong-You-Cheong JJ, Wagner BJ, Davis CJ Jr (1998) Transitional cell carcinoma of the urinary tract: radiologic-pathologic correlation. RadioGraphics 18:123–142PubMed Wong-You-Cheong JJ, Wagner BJ, Davis CJ Jr (1998) Transitional cell carcinoma of the urinary tract: radiologic-pathologic correlation. RadioGraphics 18:123–142PubMed
2.
go back to reference Keeley FX, Kulp DA, Bibbo M, et al. (1997) Diagnostic accuracy of ureteroscopic biopsy in upper tract transitional cell carcinoma. J Urol 157:33–37PubMedCrossRef Keeley FX, Kulp DA, Bibbo M, et al. (1997) Diagnostic accuracy of ureteroscopic biopsy in upper tract transitional cell carcinoma. J Urol 157:33–37PubMedCrossRef
3.
go back to reference Atasoy C, Yagci C, Fitoz S, et al. (2001) Cross-sectional imaging in ureter tumors: findings and staging accuracy of various modalities. Clin Imaging 25:197–202PubMedCrossRef Atasoy C, Yagci C, Fitoz S, et al. (2001) Cross-sectional imaging in ureter tumors: findings and staging accuracy of various modalities. Clin Imaging 25:197–202PubMedCrossRef
4.
go back to reference Quaia E, Bertolotto M, Bussani R, et al. (2001) Integration of ultrasonography, spiral CT and MRI in a case of transitional cell carcinoma of the urinary tract. Radiol Med 101:95–99PubMed Quaia E, Bertolotto M, Bussani R, et al. (2001) Integration of ultrasonography, spiral CT and MRI in a case of transitional cell carcinoma of the urinary tract. Radiol Med 101:95–99PubMed
5.
go back to reference Yazaki T, Kamiyama Y, Tomomasa H, et al. (1999) Ureteropyeloscopy in the diagnosis of patients with upper tract hematuria: an initial clinical study. Int J Urol 6:219–225PubMedCrossRef Yazaki T, Kamiyama Y, Tomomasa H, et al. (1999) Ureteropyeloscopy in the diagnosis of patients with upper tract hematuria: an initial clinical study. Int J Urol 6:219–225PubMedCrossRef
6.
go back to reference Chen GL, El-Gabry EA, Bagley DH (2000) Surveillance of upper urinary tract transitional cell carcinoma: the role of ureteroscopy, retrograde pyelography, citology and urinalysis. J Urol 164:1901–1904PubMedCrossRef Chen GL, El-Gabry EA, Bagley DH (2000) Surveillance of upper urinary tract transitional cell carcinoma: the role of ureteroscopy, retrograde pyelography, citology and urinalysis. J Urol 164:1901–1904PubMedCrossRef
7.
go back to reference Harmon WJ, Sershon PD, Blute ML, et al. (1997) Ureteroscopy: current practice and long-term complications. J Urol 157:28–32PubMedCrossRef Harmon WJ, Sershon PD, Blute ML, et al. (1997) Ureteroscopy: current practice and long-term complications. J Urol 157:28–32PubMedCrossRef
8.
go back to reference McNicholas MM, Raptopoulos VD, Schwartz RK, et al. (1998) Excretory phase CT urography for opacification of the urinary collecting system. Am J Roentgenol 170:1261–1267 McNicholas MM, Raptopoulos VD, Schwartz RK, et al. (1998) Excretory phase CT urography for opacification of the urinary collecting system. Am J Roentgenol 170:1261–1267
9.
go back to reference Chow LC, Sommer FG (2001) Multidetector CT urography with abdominal compression and three-dimensional reconstruction. Am J Roentgenol 177:849–855 Chow LC, Sommer FG (2001) Multidetector CT urography with abdominal compression and three-dimensional reconstruction. Am J Roentgenol 177:849–855
10.
go back to reference Joffe SA, Servaes S, Okon S, et al. (2003) Multi-detector row CT urography in the evaluation of hematuria. RadioGraphics 23:1441–1456PubMedCrossRef Joffe SA, Servaes S, Okon S, et al. (2003) Multi-detector row CT urography in the evaluation of hematuria. RadioGraphics 23:1441–1456PubMedCrossRef
12.
go back to reference Delvecchio FC, Auge BK, Weizer AZ, et al. (2002) Computed tomography urography, three-dimensional computed tomography and virtual endoscopy. Curr Opin Urol 12:137–142PubMedCrossRef Delvecchio FC, Auge BK, Weizer AZ, et al. (2002) Computed tomography urography, three-dimensional computed tomography and virtual endoscopy. Curr Opin Urol 12:137–142PubMedCrossRef
13.
go back to reference Kim JK, Cho KS (2003) CT urography and virtual endoscopy: promising imaging modalities for urinary tract evaluation. Br J Radiol 76:199–209PubMedCrossRef Kim JK, Cho KS (2003) CT urography and virtual endoscopy: promising imaging modalities for urinary tract evaluation. Br J Radiol 76:199–209PubMedCrossRef
14.
go back to reference Rimondini A, Morra A, Bertolotto M, et al. (2001) Spiral-CT with multiplanar reconstructions (MPRs) in the evaluation of ureteral neoplasms: preliminary results. Radiol Med 101:459–465PubMed Rimondini A, Morra A, Bertolotto M, et al. (2001) Spiral-CT with multiplanar reconstructions (MPRs) in the evaluation of ureteral neoplasms: preliminary results. Radiol Med 101:459–465PubMed
15.
go back to reference Caoili EM, Cohan RH, Korobkin M, et al. (2002) Urinary tract abnormalities: initial experience with multi-detector row CT urography. Radiology 222:353–360PubMedCrossRef Caoili EM, Cohan RH, Korobkin M, et al. (2002) Urinary tract abnormalities: initial experience with multi-detector row CT urography. Radiology 222:353–360PubMedCrossRef
16.
go back to reference Bechtold RB, Chen MYM, Dyer RB, et al. (1997) CT of the ureteral wall. Am J Roentgenol 170:1283–1289 Bechtold RB, Chen MYM, Dyer RB, et al. (1997) CT of the ureteral wall. Am J Roentgenol 170:1283–1289
17.
go back to reference Caoili EM, Cohan RH, Inampudi P, et al. (2005) MDCT urography of upper tract urothelial neoplasms. Am J Roentgenol 184:1873–1881 Caoili EM, Cohan RH, Inampudi P, et al. (2005) MDCT urography of upper tract urothelial neoplasms. Am J Roentgenol 184:1873–1881
18.
go back to reference Fritz GA, Schoellnast H, Deutschmann HA, et al. (2006) Multiphasic multidetector-row CT (MDCT) in detection and staging of transitional cell carcinomas of the upper urinary tract. Eur Radiol 16:1244–1252, 2006PubMedCrossRef Fritz GA, Schoellnast H, Deutschmann HA, et al. (2006) Multiphasic multidetector-row CT (MDCT) in detection and staging of transitional cell carcinomas of the upper urinary tract. Eur Radiol 16:1244–1252, 2006PubMedCrossRef
19.
go back to reference Browne RF, Meehan CP, Colville J, et al. (2005) Transitional cell carcinoma of the upper urinary tract: spectrum of imaging findings. RadioGraphics 25:1609–1627PubMedCrossRef Browne RF, Meehan CP, Colville J, et al. (2005) Transitional cell carcinoma of the upper urinary tract: spectrum of imaging findings. RadioGraphics 25:1609–1627PubMedCrossRef
20.
go back to reference Chou CP, Wu TT, Levensen RB, et al. (2007) Ureteral fibroethelial polyp diagnosed preoperatively on virtual CT ureteroscopy. Abdom Imaging 32:421–423PubMedCrossRef Chou CP, Wu TT, Levensen RB, et al. (2007) Ureteral fibroethelial polyp diagnosed preoperatively on virtual CT ureteroscopy. Abdom Imaging 32:421–423PubMedCrossRef
21.
go back to reference Grasso M, Bagley D (1998) Small diameter, actively defectable, flexible ureteropyeloscopy. J Urol 160:1648–1653PubMedCrossRef Grasso M, Bagley D (1998) Small diameter, actively defectable, flexible ureteropyeloscopy. J Urol 160:1648–1653PubMedCrossRef
22.
go back to reference Takebayashi S, Hosaka M, Takase K, et al. (1999) Computerized tomography nephroscopic images of renal pelvic carcinoma. J Urol 162:315–318PubMedCrossRef Takebayashi S, Hosaka M, Takase K, et al. (1999) Computerized tomography nephroscopic images of renal pelvic carcinoma. J Urol 162:315–318PubMedCrossRef
23.
go back to reference Takebayashi S, Hosaka M, Kubota Y, et al. (2000) Computerized tomographic ureteroscopy for diagnosing ureteral tumors. J Urol 163:42–46PubMedCrossRef Takebayashi S, Hosaka M, Kubota Y, et al. (2000) Computerized tomographic ureteroscopy for diagnosing ureteral tumors. J Urol 163:42–46PubMedCrossRef
24.
go back to reference McTavish JD, Jinzaki M, Zou KH, et al. (2002) Multi-detector row CT urography: comparison of strategies for depicting the normal urinary collecting system. Radiology 225:783–790PubMedCrossRef McTavish JD, Jinzaki M, Zou KH, et al. (2002) Multi-detector row CT urography: comparison of strategies for depicting the normal urinary collecting system. Radiology 225:783–790PubMedCrossRef
25.
go back to reference Noroozian M, Cohan RH, Caoili EM, et al. (2004) Multislice CT urography: state of the art. Br J Radiol 77:S74–S86PubMedCrossRef Noroozian M, Cohan RH, Caoili EM, et al. (2004) Multislice CT urography: state of the art. Br J Radiol 77:S74–S86PubMedCrossRef
26.
go back to reference Silverman SG, Akbar SA, Mortele KJ, et al. (2006) Multi-detector row CT urography of normal urinary collecting system: furosemide versus saline as adjunct to contrast medium. Radiology 240:749–755PubMedCrossRef Silverman SG, Akbar SA, Mortele KJ, et al. (2006) Multi-detector row CT urography of normal urinary collecting system: furosemide versus saline as adjunct to contrast medium. Radiology 240:749–755PubMedCrossRef
27.
go back to reference Kemper J, Regier M, Stork A, et al. (2006) Improved visualization of the urinary tract in multidetector CT urography (MDCTU): analysis of individual acquisition delay and opacification using furosemide and low-dose test images. J Comput Assist Tomogr 30:751–757PubMedCrossRef Kemper J, Regier M, Stork A, et al. (2006) Improved visualization of the urinary tract in multidetector CT urography (MDCTU): analysis of individual acquisition delay and opacification using furosemide and low-dose test images. J Comput Assist Tomogr 30:751–757PubMedCrossRef
28.
go back to reference Neri E, Boraschi P, Caramella D, et al. (2000) MR virtual endoscopy of the upper urinary tract. Am J Roentgenol 175:1697–1702 Neri E, Boraschi P, Caramella D, et al. (2000) MR virtual endoscopy of the upper urinary tract. Am J Roentgenol 175:1697–1702
29.
go back to reference Kagadis GC, Siablis D, Liatsikos EN, et al. (2006) Virtual endoscopy of the urinary tract. Asian J Androl 8:31–38PubMedCrossRef Kagadis GC, Siablis D, Liatsikos EN, et al. (2006) Virtual endoscopy of the urinary tract. Asian J Androl 8:31–38PubMedCrossRef
Metadata
Title
Computerized tomography virtual endoscopy in evaluation of upper urinary tract tumors: initial experience
Authors
Giuseppe Battista
Claudia Sassi
Riccardo Schiavina
Alessandro Franceschelli
Emanuela Baglivo
Giuseppe Martorana
Romeo Canini
Publication date
01-01-2009
Publisher
Springer-Verlag
Published in
Abdominal Radiology / Issue 1/2009
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-008-9387-5

Other articles of this Issue 1/2009

Abdominal Radiology 1/2009 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.