Skip to main content
Top
Published in: Knee Surgery, Sports Traumatology, Arthroscopy 11/2023

25-07-2023 | Computed Tomography | KNEE

Long leg radiographs underestimate the degree of constitutional varus limb alignment and joint line obliquity in comparison with computed tomography: a radiographic study

Authors: Payam Tarassoli, Luke E. Corban, Jil A. Wood, Andrew Sergis, Darren B. Chen, Samuel J. MacDessi

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 11/2023

Login to get access

Abstract

Purpose

The purpose of this study was to understand if differences exist between computed tomography (CT) and long leg radiographs (LLR) when defining coronal plane alignment of the lower limb in total knee arthroplasty (TKA). It aimed to identify any such differences between the two imaging modalities by quantifying constitutional limb alignment (arithmetic hip–knee–ankle angle (aHKA), joint line obliquity (JLO) and Coronal Plane Alignment of the Knee (CPAK) type within the same population.

Methods

A retrospective radiographic study compared pre-operative LLR and CT measurements in patients undergoing robotic-assisted TKA. The aHKA, JLO and CPAK types were calculated after measuring the medial proximal tibial angle (MPTA) and lateral distal femoral angle (LDFA). The primary outcomes were the mean differences in aHKA (MPTA−LDFA), JLO (MPTA + LDFA) and proportions of CPAK types between LLR and CT groups. The secondary outcomes were the differences in CT-derived MPTA values based on four different tibial sagittal landmarks.

Results

After exclusions, 465 imaging sets were analysed in 394 patients. There was a statistically significant mean difference between LLR and CT, respectively, for both MPTA (87.5° vs. 86.2°; p < 0.01) and LDFA (88.7° vs. 87.3°; p < 0.01). There were also statistically significant differences for aHKA (− 0.2° vs. − 1.1°) and JLO (175.1° vs. 173.4°) for LLR and CT, respectively (both p < 0.01). CT increased the proportion of patients with CPAK Type I (constitutional varus aHKA, apex distal JLO) and CPAK Type II (neutral aHKA, apex distal JLO), and decreased numbers of CPAK Types III–VI. There were significant mean differences in the MPTA using varying sagittal landmarks.

Conclusion

Alignment determined by LLRs underestimates the magnitude of both constitutional varus alignment and joint line obliquity compared to CT, differences that notably increase the proportions of patients included in CPAK Types I and II. These distinctions are primarily due to underestimation of proximal tibial varus when measured on LLRs compared to CT, which more specifically defines articular weight-bearing points.

Level of evidence

III.
Literature
1.
go back to reference Ahrend MD, Baumgartner H, Ihle C, Histing T, Schroter S, Finger F (2022) Influence of axial limb rotation on radiographic lower limb alignment: a systematic review. Arch Orthop Trauma Surg 142(11):3349–3366CrossRefPubMed Ahrend MD, Baumgartner H, Ihle C, Histing T, Schroter S, Finger F (2022) Influence of axial limb rotation on radiographic lower limb alignment: a systematic review. Arch Orthop Trauma Surg 142(11):3349–3366CrossRefPubMed
2.
go back to reference Beckers L, Colyn W, Bellemans J, Victor J, Vandekerckhove PJ (2022) The contralateral limb is no reliable reference to restore coronal alignment in TKA. Knee Surg Sports Traumatol Arthrosc 30(2):477–487CrossRefPubMed Beckers L, Colyn W, Bellemans J, Victor J, Vandekerckhove PJ (2022) The contralateral limb is no reliable reference to restore coronal alignment in TKA. Knee Surg Sports Traumatol Arthrosc 30(2):477–487CrossRefPubMed
3.
go back to reference Bellemans J, Colyn W, Vandenneucker H, Victor J (2012) The Chitranjan Ranawat award: Is neutral mechanical alignment normal for all patients? The concept of constitutional varus. Clin Orthop Relat Res 470(1):45–53CrossRefPubMed Bellemans J, Colyn W, Vandenneucker H, Victor J (2012) The Chitranjan Ranawat award: Is neutral mechanical alignment normal for all patients? The concept of constitutional varus. Clin Orthop Relat Res 470(1):45–53CrossRefPubMed
4.
go back to reference Chauhan SK, Clark GW, Lloyd S, Scott RG, Breidahl W, Sikorski JM (2004) Computer-assisted total knee replacement: a controlled cadaver study using a multi-parameter quantitative CT assessment of alignment (the Perth CT Protocol). J Bone Joint Surg Br 86(6):818–823CrossRefPubMed Chauhan SK, Clark GW, Lloyd S, Scott RG, Breidahl W, Sikorski JM (2004) Computer-assisted total knee replacement: a controlled cadaver study using a multi-parameter quantitative CT assessment of alignment (the Perth CT Protocol). J Bone Joint Surg Br 86(6):818–823CrossRefPubMed
5.
go back to reference Evans JT, Walker RW, Evans JP, Blom AW, Sayers A, Whitehouse MR (2019) How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up. Lancet 393(10172):655–663CrossRefPubMedPubMedCentral Evans JT, Walker RW, Evans JP, Blom AW, Sayers A, Whitehouse MR (2019) How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up. Lancet 393(10172):655–663CrossRefPubMedPubMedCentral
6.
go back to reference Gbejuade HO, White P, Hassaballa M, Porteous AJ, Robinson JR, Murray JR (2014) Do long leg supine CT scanograms correlate with weight-bearing full-length radiographs to measure lower limb coronal alignment? Knee 21(2):549–552CrossRefPubMed Gbejuade HO, White P, Hassaballa M, Porteous AJ, Robinson JR, Murray JR (2014) Do long leg supine CT scanograms correlate with weight-bearing full-length radiographs to measure lower limb coronal alignment? Knee 21(2):549–552CrossRefPubMed
7.
go back to reference Gilbert S, Chen T, Hutchinson ID, Choi D, Voigt C, Warren RF et al (2014) Dynamic contact mechanics on the tibial plateau of the human knee during activities of daily living. J Biomech 47(9):2006–2012CrossRefPubMed Gilbert S, Chen T, Hutchinson ID, Choi D, Voigt C, Warren RF et al (2014) Dynamic contact mechanics on the tibial plateau of the human knee during activities of daily living. J Biomech 47(9):2006–2012CrossRefPubMed
8.
go back to reference Gkiatas I, Karasavvidis T, Sharma AK, Xiang W, Malahias MA, Chalmers BP et al (2022) Highly cross-linked polyethylene in primary total knee arthroplasty is associated with a lower rate of revision for aseptic loosening: a meta-analysis of 962,467 cases. Arch Orthop Trauma Surg 142(6):1177–1184CrossRefPubMed Gkiatas I, Karasavvidis T, Sharma AK, Xiang W, Malahias MA, Chalmers BP et al (2022) Highly cross-linked polyethylene in primary total knee arthroplasty is associated with a lower rate of revision for aseptic loosening: a meta-analysis of 962,467 cases. Arch Orthop Trauma Surg 142(6):1177–1184CrossRefPubMed
9.
go back to reference Griffiths-Jones W, Chen DB, Harris IA, Bellemans J, MacDessi SJ (2021) Arithmetic hip-knee-ankle angle (aHKA): an algorithm for estimating constitutional lower limb alignment in the arthritic patient population. Bone Jt Open 2(5):351–358CrossRefPubMedPubMedCentral Griffiths-Jones W, Chen DB, Harris IA, Bellemans J, MacDessi SJ (2021) Arithmetic hip-knee-ankle angle (aHKA): an algorithm for estimating constitutional lower limb alignment in the arthritic patient population. Bone Jt Open 2(5):351–358CrossRefPubMedPubMedCentral
10.
go back to reference Hazratwala K, O’Callaghan WB, Dhariwal S, Knee G, Wilkinson MPR (2022) Wide variation in tibial slopes and trochlear angles in the arthritic knee: a CT evaluation of 4116 pre-operative knees. Knee Surg Sports Traumatol Arthrosc 30(9):3049–3060CrossRefPubMed Hazratwala K, O’Callaghan WB, Dhariwal S, Knee G, Wilkinson MPR (2022) Wide variation in tibial slopes and trochlear angles in the arthritic knee: a CT evaluation of 4116 pre-operative knees. Knee Surg Sports Traumatol Arthrosc 30(9):3049–3060CrossRefPubMed
11.
go back to reference Hess S, Moser LB, Amsler F, Behrend H, Hirschmann MT (2019) Highly variable coronal tibial and femoral alignment in osteoarthritic knees: a systematic review. Knee Surg Sports Traumatol Arthrosc 27(5):1368–1377CrossRefPubMed Hess S, Moser LB, Amsler F, Behrend H, Hirschmann MT (2019) Highly variable coronal tibial and femoral alignment in osteoarthritic knees: a systematic review. Knee Surg Sports Traumatol Arthrosc 27(5):1368–1377CrossRefPubMed
12.
go back to reference Hess S, Moser LB, Robertson EL, Behrend H, Amsler F, Iordache E et al (2022) Osteoarthritic and non-osteoarthritic patients show comparable coronal knee joint line orientations in a cross-sectional study based on 3D reconstructed CT images. Knee Surg Sports Traumatol Arthrosc 30(2):407–418CrossRefPubMed Hess S, Moser LB, Robertson EL, Behrend H, Amsler F, Iordache E et al (2022) Osteoarthritic and non-osteoarthritic patients show comparable coronal knee joint line orientations in a cross-sectional study based on 3D reconstructed CT images. Knee Surg Sports Traumatol Arthrosc 30(2):407–418CrossRefPubMed
13.
go back to reference Hirschmann MT, Moser LB, Amsler F, Behrend H, Leclercq V, Hess S (2019) Phenotyping the knee in young non-osteoarthritic knees shows a wide distribution of femoral and tibial coronal alignment. Knee Surg Sports Traumatol Arthrosc 27(5):1385–1393CrossRefPubMed Hirschmann MT, Moser LB, Amsler F, Behrend H, Leclercq V, Hess S (2019) Phenotyping the knee in young non-osteoarthritic knees shows a wide distribution of femoral and tibial coronal alignment. Knee Surg Sports Traumatol Arthrosc 27(5):1385–1393CrossRefPubMed
14.
go back to reference Holme TJ, Henckel J, Hartshorn K, Cobb JP, Hart AJ (2015) Computed tomography scanogram compared to long leg radiograph for determining axial knee alignment. Acta Orthop 86(4):440–443CrossRefPubMedPubMedCentral Holme TJ, Henckel J, Hartshorn K, Cobb JP, Hart AJ (2015) Computed tomography scanogram compared to long leg radiograph for determining axial knee alignment. Acta Orthop 86(4):440–443CrossRefPubMedPubMedCentral
15.
go back to reference Howell SM, Howell SJ, Kuznik KT, Cohen J, Hull ML (2013) Does a kinematically aligned total knee arthroplasty restore function without failure regardless of alignment category? Clin Orthop Relat Res 471(3):1000–1007CrossRefPubMed Howell SM, Howell SJ, Kuznik KT, Cohen J, Hull ML (2013) Does a kinematically aligned total knee arthroplasty restore function without failure regardless of alignment category? Clin Orthop Relat Res 471(3):1000–1007CrossRefPubMed
16.
go back to reference Hsu CE, Chen CP, Wang SP, Huang JT, Tong KM, Huang KC (2022) Validation and modification of the coronal plane alignment of the knee classification in the Asian population. Bone Jt Open 3(3):211–217CrossRefPubMedPubMedCentral Hsu CE, Chen CP, Wang SP, Huang JT, Tong KM, Huang KC (2022) Validation and modification of the coronal plane alignment of the knee classification in the Asian population. Bone Jt Open 3(3):211–217CrossRefPubMedPubMedCentral
17.
go back to reference Keenan OJF, Holland G, Maempel JF, Keating JF, Scott CEH (2020) Correlations between radiological classification systems and confirmed cartilage loss in severe knee osteoarthritis. Bone Joint J 102-B(3):301–309CrossRefPubMed Keenan OJF, Holland G, Maempel JF, Keating JF, Scott CEH (2020) Correlations between radiological classification systems and confirmed cartilage loss in severe knee osteoarthritis. Bone Joint J 102-B(3):301–309CrossRefPubMed
18.
go back to reference Klasan A, Putnis SE, Grasso S, Neri T, Coolican MR (2020) Conventional instruments are more accurate for measuring the depth of the tibial cut than computer-assisted surgery in total knee arthroplasty: a prospective study. Arch Orthop Trauma Surg 140(6):801–806CrossRefPubMed Klasan A, Putnis SE, Grasso S, Neri T, Coolican MR (2020) Conventional instruments are more accurate for measuring the depth of the tibial cut than computer-assisted surgery in total knee arthroplasty: a prospective study. Arch Orthop Trauma Surg 140(6):801–806CrossRefPubMed
19.
go back to reference Leon-Munoz VJ, Lopez-Lopez M, Martinez-Martinez F, Santonja-Medina F (2020) Comparison of weight-bearing full-length radiographs and computed-tomography-scan-based three-dimensional models in the assessment of knee joint coronal alignment. Knee 27(2):543–551CrossRefPubMed Leon-Munoz VJ, Lopez-Lopez M, Martinez-Martinez F, Santonja-Medina F (2020) Comparison of weight-bearing full-length radiographs and computed-tomography-scan-based three-dimensional models in the assessment of knee joint coronal alignment. Knee 27(2):543–551CrossRefPubMed
20.
go back to reference Lewis PL, Graves SE, de Steiger RN, Campbell DG, Peng Y, Hatton A et al (2020) Does knee prosthesis survivorship improve when implant designs change? Findings from the Australian orthopaedic association national joint replacement registry. Clin Orthop Relat Res 478(6):1156–1172CrossRefPubMedPubMedCentral Lewis PL, Graves SE, de Steiger RN, Campbell DG, Peng Y, Hatton A et al (2020) Does knee prosthesis survivorship improve when implant designs change? Findings from the Australian orthopaedic association national joint replacement registry. Clin Orthop Relat Res 478(6):1156–1172CrossRefPubMedPubMedCentral
21.
go back to reference Lustig S, Sappey-Marinier E, Fary C, Servien E, Parratte S, Batailler C (2021) Personalized alignment in total knee arthroplasty: current concepts. SICOT J 7:19CrossRefPubMedPubMedCentral Lustig S, Sappey-Marinier E, Fary C, Servien E, Parratte S, Batailler C (2021) Personalized alignment in total knee arthroplasty: current concepts. SICOT J 7:19CrossRefPubMedPubMedCentral
22.
go back to reference MacDessi SJ (2021) Restricted kinematic alignment in total knee arthroplasty: scientific exploration involving detailed planning, precise execution, and knowledge of when to abort. Arthroplast Today 10:24–26CrossRefPubMedPubMedCentral MacDessi SJ (2021) Restricted kinematic alignment in total knee arthroplasty: scientific exploration involving detailed planning, precise execution, and knowledge of when to abort. Arthroplast Today 10:24–26CrossRefPubMedPubMedCentral
23.
go back to reference MacDessi SJ, Griffiths-Jones W, Harris IA, Bellemans J, Chen DB (2020) The arithmetic HKA (aHKA) predicts the constitutional alignment of the arthritic knee compared to the normal contralateral knee: a matched-pairs radiographic study. Bone Jt Open 1(7):339–345CrossRefPubMedPubMedCentral MacDessi SJ, Griffiths-Jones W, Harris IA, Bellemans J, Chen DB (2020) The arithmetic HKA (aHKA) predicts the constitutional alignment of the arthritic knee compared to the normal contralateral knee: a matched-pairs radiographic study. Bone Jt Open 1(7):339–345CrossRefPubMedPubMedCentral
24.
go back to reference MacDessi SJ, Griffiths-Jones W, Harris IA, Bellemans J, Chen DB (2021) Coronal plane alignment of the knee (CPAK) classification. Bone Joint J 103-B(2):329–337CrossRefPubMedPubMedCentral MacDessi SJ, Griffiths-Jones W, Harris IA, Bellemans J, Chen DB (2021) Coronal plane alignment of the knee (CPAK) classification. Bone Joint J 103-B(2):329–337CrossRefPubMedPubMedCentral
25.
go back to reference MacDessi SJ, Oussedik S, Abdel MP, Victor J, Pagnano MW, Haddad FS (2023) The language of knee alignment: updated definitions and considerations for reporting outcomes in total knee arthroplasty. Bone Joint J 105-B(2):102–108CrossRefPubMed MacDessi SJ, Oussedik S, Abdel MP, Victor J, Pagnano MW, Haddad FS (2023) The language of knee alignment: updated definitions and considerations for reporting outcomes in total knee arthroplasty. Bone Joint J 105-B(2):102–108CrossRefPubMed
26.
go back to reference Nguyen HC, Gielis WP, van Egmond N, Weinans H, Slump CH, Sakkers RJB et al (2021) The need for a standardized whole leg radiograph guideline: the effects of knee flexion, leg rotation, and X-ray beam height. J Cart Jt Preserv 1:100022 Nguyen HC, Gielis WP, van Egmond N, Weinans H, Slump CH, Sakkers RJB et al (2021) The need for a standardized whole leg radiograph guideline: the effects of knee flexion, leg rotation, and X-ray beam height. J Cart Jt Preserv 1:100022
27.
go back to reference Ogawa H, Nakamura Y, Sengoku M, Shimokawa T, Sohmiya K, Ohnishi K et al (2022) Medial proximal tibial angle at the posterior tibial plateau represents the pre-arthritic constitutional medial proximal tibial angle in anterior cruciate ligament-intact, advanced osteoarthritis of the knee. Knee Surg Sports Traumatol Arthrosc 30(9):2941–2947CrossRefPubMed Ogawa H, Nakamura Y, Sengoku M, Shimokawa T, Sohmiya K, Ohnishi K et al (2022) Medial proximal tibial angle at the posterior tibial plateau represents the pre-arthritic constitutional medial proximal tibial angle in anterior cruciate ligament-intact, advanced osteoarthritis of the knee. Knee Surg Sports Traumatol Arthrosc 30(9):2941–2947CrossRefPubMed
28.
go back to reference Paley D (2003) Principles of deformity correction. Springer-Verlag, Heidelberg Paley D (2003) Principles of deformity correction. Springer-Verlag, Heidelberg
29.
go back to reference Paternostre F, Schwab PE, Thienpont E (2014) The difference between weight-bearing and non-weight-bearing alignment in patient-specific instrumentation planning. Knee Surg Sports Traumatol Arthrosc 22(3):674–679CrossRefPubMed Paternostre F, Schwab PE, Thienpont E (2014) The difference between weight-bearing and non-weight-bearing alignment in patient-specific instrumentation planning. Knee Surg Sports Traumatol Arthrosc 22(3):674–679CrossRefPubMed
30.
go back to reference Sappey-Marinier E, Batailler C, Swan J, Malatray M, Cheze L, Servien E et al (2022) Primary osteoarthritic knees have more varus coronal alignment of the femur compared to young non-arthritic knees in a large cohort study. Knee Surg Sports Traumatol Arthrosc 30(2):428–436CrossRefPubMed Sappey-Marinier E, Batailler C, Swan J, Malatray M, Cheze L, Servien E et al (2022) Primary osteoarthritic knees have more varus coronal alignment of the femur compared to young non-arthritic knees in a large cohort study. Knee Surg Sports Traumatol Arthrosc 30(2):428–436CrossRefPubMed
31.
go back to reference Schlatterer B, Linares JM, Chabrand P, Sprauel JM, Argenson JN (2014) Influence of the optical system and anatomic points on computer-assisted total knee arthroplasty. Orthop Traumatol Surg Res 100(4):395–402CrossRefPubMed Schlatterer B, Linares JM, Chabrand P, Sprauel JM, Argenson JN (2014) Influence of the optical system and anatomic points on computer-assisted total knee arthroplasty. Orthop Traumatol Surg Res 100(4):395–402CrossRefPubMed
32.
go back to reference Schoenmakers DAL, Feczko PZ, Boonen B, Schotanus MGM, Kort NP, Emans PJ (2017) Measurement of lower limb alignment: there are within-person differences between weight-bearing and non-weight-bearing measurement modalities. Knee Surg Sports Traumatol Arthrosc 25(11):3569–3575CrossRefPubMedPubMedCentral Schoenmakers DAL, Feczko PZ, Boonen B, Schotanus MGM, Kort NP, Emans PJ (2017) Measurement of lower limb alignment: there are within-person differences between weight-bearing and non-weight-bearing measurement modalities. Knee Surg Sports Traumatol Arthrosc 25(11):3569–3575CrossRefPubMedPubMedCentral
33.
go back to reference Solayar GN, Chinappa J, Harris IA, Chen DB, Macdessi SJ (2017) A comparison of plain radiography with computer tomography in determining coronal and sagittal alignments following total knee arthroplasty. Malays Orthop J 11(2):45–52CrossRefPubMedPubMedCentral Solayar GN, Chinappa J, Harris IA, Chen DB, Macdessi SJ (2017) A comparison of plain radiography with computer tomography in determining coronal and sagittal alignments following total knee arthroplasty. Malays Orthop J 11(2):45–52CrossRefPubMedPubMedCentral
34.
go back to reference Toyooka S, Osaki Y, Masuda H, Arai N, Miyamoto W, Ando S et al (2023) Distribution of coronal plane alignment of the knee classification in patients with knee osteoarthritis in Japan. J Knee Surg 36(7):738–743CrossRefPubMed Toyooka S, Osaki Y, Masuda H, Arai N, Miyamoto W, Ando S et al (2023) Distribution of coronal plane alignment of the knee classification in patients with knee osteoarthritis in Japan. J Knee Surg 36(7):738–743CrossRefPubMed
35.
go back to reference Weinberg DS, Williamson DF, Gebhart JJ, Knapik DM, Voos JE (2017) Differences in medial and lateral posterior tibial slope: an osteological review of 1090 tibiae comparing age, sex, and race. Am J Sports Med 45(1):106–113CrossRefPubMed Weinberg DS, Williamson DF, Gebhart JJ, Knapik DM, Voos JE (2017) Differences in medial and lateral posterior tibial slope: an osteological review of 1090 tibiae comparing age, sex, and race. Am J Sports Med 45(1):106–113CrossRefPubMed
36.
go back to reference Winter A, Ferguson K, Syme B, McMillan J, Holt G (2014) Pre-operative analysis of lower limb coronal alignment: a comparison of supine MRI versus standing full-length alignment radiographs. Knee 21(6):1084–1087CrossRefPubMed Winter A, Ferguson K, Syme B, McMillan J, Holt G (2014) Pre-operative analysis of lower limb coronal alignment: a comparison of supine MRI versus standing full-length alignment radiographs. Knee 21(6):1084–1087CrossRefPubMed
37.
go back to reference Zhang Y, Wang J, Xiao J, Zhao L, Li ZH, Yan G et al (2014) Measurement and comparison of tibial posterior slope angle in different methods based on three-dimensional reconstruction. Knee 21(3):694–698CrossRefPubMed Zhang Y, Wang J, Xiao J, Zhao L, Li ZH, Yan G et al (2014) Measurement and comparison of tibial posterior slope angle in different methods based on three-dimensional reconstruction. Knee 21(3):694–698CrossRefPubMed
Metadata
Title
Long leg radiographs underestimate the degree of constitutional varus limb alignment and joint line obliquity in comparison with computed tomography: a radiographic study
Authors
Payam Tarassoli
Luke E. Corban
Jil A. Wood
Andrew Sergis
Darren B. Chen
Samuel J. MacDessi
Publication date
25-07-2023
Publisher
Springer Berlin Heidelberg
Published in
Knee Surgery, Sports Traumatology, Arthroscopy / Issue 11/2023
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-023-07505-w

Other articles of this Issue 11/2023

Knee Surgery, Sports Traumatology, Arthroscopy 11/2023 Go to the issue